Bi2MP_GENP GENETICS FOR BASIC EDUCATION

Faculty of Education
Autumn 2012
Extent and Intensity
2/0/0. 4 credit(s). Type of Completion: zk (examination).
Teacher(s)
Mgr. Martina Jančová, Ph.D. (lecturer)
Guaranteed by
doc. RNDr. Boris Rychnovský, CSc.
Department of Biology – Faculty of Education
Contact Person: Mgr. Martina Jančová, Ph.D.
Supplier department: Department of Biology – Faculty of Education
Timetable
Thu 13:00–14:40 učebna 63
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
At the end of this course, students should be able to:
- explain basic genetics terms, Mendel´s and Morgan´s laws and basics of cytogenetics.
- comprehend and explain general principles of heredity and variability of living organisms occuring in both uni- and multicellular organisms.
- understand that transmission of hereditary predispositions during the sexual reproduction process is a source of traits variability for all diploid organisms - students explain this fact on their own examples.
- aware of the specifics of human traits heredity and the significance of human genome research.
- apply the genetics of individual organisms to the genetics of populations.
- appreciate on the basis of acquired knowledge an importance of hereditary predispositions that can be manifested to the form of individuum concrete traits and use this knowledge in pedagogic employment and in children education.
Syllabus
  • 1. Basic genetic terminology - heredity, variability, gene, alleles and their mutual relations, genotype, phenotype, genome, gene pool, allelia multipla etc. Laws of probability calculation. Model organisms in genetics.
  • 2. Basic genetic laws: Mendel’s phenotypic and genotypic laws. Hybridism – monohybridism, dihybridism, polyhybridism. Backcross, reciprocal cross.
  • 3. Historical development and origin of genetics as a scientific discipline. Importance of J. G. Mendel (+ educational film). Current development and importance of genetics.
  • 4. Basics of cytogenetics I.: Structure and importance of chromosomes, chromosomal determination of sex, chromosomal abnormalities.
  • 5. Basics of cytogenetics II.: Cell cyle. Cell death. Mitosis and meiosis course. Genetic impact of meiosis. Human gametogenesis.
  • 6. Nucleic acids, proteins - importance, structure. Replication, transcription, translation. Genetic information expression. Mutations – classification, detection, their causes and consequences.
  • 7. Causes of exceptions from theoretical segregation ratios defined by Mendel - penetrance, expresivity, sex-linked traits, sex-controlled and -influenced traits, non-allelic genes interaction, maternal heredity.
  • 8. Morgan’s laws. Genetic bond – genetic mapping. Hypothesis of mechanism and importance of crossing over. Morgan´s and Bateson´s numbers.
  • 9. Study of man genetics - methods, limitation. Mariage of relations. Medical genetics. Heredity of quantitative traits of man. Heredity of intelligence, talent.
  • 10. Genetics of populations I.: Autogamic and panmictic population – characteristics. Hardy-Weinberg’s law of genetic equilibrium - consequences, calculation of allelic and genotypic frequencies.
  • 11. Genetics of populations II.: Selection, mutation, populations structure – genetic drift, migration.
Literature
    recommended literature
  • SNUSTAD, D. Peter and Michael J. SIMMONS. Genetika. Translated by Jiřina Relichová. 1. vyd. Brno: Masarykova univerzita, 2009, 871 pp. ISBN 978-80-210-4852-2. Online knihkupectví Munipress info
  • ALBERTS, Bruce. Základy buněčné biologie : úvod do molekulární biologie buňky. Translated by Arnošt Kotyk. 2. vyd. Ústí nad Labem: Espero Publishing, 2004, xxvi, 630. ISBN 8090290620. info
    not specified
  • KOČÁREK, Eduard. Genetika : obecná genetika a cytogenetika, molekulární biologie, biotechnologie, genomika. Illustrated by Jan Maget. 2. vydání. Praha: Scientia, 2008, 211 stran. ISBN 9788086960364. info
  • ŠMARDA, Jan. Genetika : pro gymnázia. 1. vyd. Praha: Fortuna, 2003, 143 s. ISBN 8071688517. info
  • NEČAS, Oldřich. Obecná biologie : pro lékařské fakulty. 3. přeprac. vyd., v nakl. H. Jinočany: H & H, 2000, 554 s. ISBN 8086022463. info
  • HAVELKOVÁ, Marie. Pravděpodobnost a její význam v dědičnosti. 3. přeprac. vyd. Brno: Univerzita J.E.Purkyně, 1988, 39 s. info
  • NUSSBAUM, Robert L., Roderick R. MCINNES, Huntington F. WILLARD, James THOMPSON and Margaret Wilson THOMPSON. Klinická genetika : Thompson & Thompson. Translated by Petr Goetz. Vyd. 1. Praha: Triton, 2004, 426, lix. ISBN 8072544756. info
  • SOUKUP, František, Jiří VYMLÁTIL and Eva TOPINKOVÁ. Biologie člověka : pro bakalářské studium na lékařských fakultách. Edited by Berta Otová - Jan Kapras. 1. vyd. Praha: Karolinum, 1997, 102 s. ISBN 8071845043. info
  • ROSYPAL, Stanislav. Úvod do molekulární biologie. Třetí inovované vydání. Brno, 1998, 300 pp. Díl I. Informační makromolekuly. ISBN 80-902562-0-1. URL info
  • ROSYPAL, Stanislav. Úvod do molekulární biologie. Třetí inovované vydání. Brno, 1999, 300 pp. Díl II. Molekulární biologie eukaryot. ISBN 80-902562-1-X. URL info
  • RELICHOVÁ, Jiřina. Genetika populací. 1. vyd. Brno: Masarykova univerzita, 2009, 187 s. ISBN 9788021047952. URL info
  • ROSYPAL, Stanislav, Jiří DOŠKAŘ, Roman PANTŮČEK, Jana KAILEROVÁ, Jiřina RELICHOVÁ, Vladislava RŮŽIČKOVÁ, Jan ŠMARDA, Jan ŠMARDA and Jiří ŠTĚPÁN. TERMINOLOGIE MOLEKULÁRNÍ BIOLOGIE. České odborné termíny, definice a anglické ekvivalenty (Terminology of molecular biology). První vydání. Brno: Vydavatel Prof. RNDr. Stanislav Rosypal, DrSc. Vodova 80, 612 00 Brno, 2001, 300 pp. ISBN 80-902562-3-6. URL info
Teaching methods
Theoretical preparation – lectures supported by chosen extracts from special video programmes.
The topic of each lecture and recommended literature will be provided one week in advance.
Each lecture will be finished by its revision through colloquy. Students will discuss new terms and context which were presented and explained during the lecture.
Assessment methods
The whole course is finished by an oral exam – a student answers and explains two theoretical topics from general genetics which he/she has selected from list.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
The course is also listed under the following terms Spring 2004, Spring 2005, Spring 2006, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017.
  • Enrolment Statistics (Autumn 2012, recent)
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