aF1FY1_13 Physical Pharmacy

Faculty of Pharmacy
Spring 2026
Extent and Intensity
2/2/0. 5 credit(s). Type of Completion: zk (examination).
In-person direct teaching
Teacher(s)
doc. Mgr. Jan Muselík, Ph.D. (lecturer)
prof. PharmDr. Mgr. David Vetchý, Ph.D. (lecturer)
Ing. Marie-Anna Bajerová (seminar tutor)
Ing. Jitka Halvová (seminar tutor)
Mgr. Sylvie Pavloková, Ph.D. (seminar tutor)
PharmDr. Jiří Zeman, Ph.D. (seminar tutor)
Dagmar Hudecová (assistant)
Ing. Adéla Sopoušková (assistant)
Aneta Škrháková, DiS. (assistant)
Guaranteed by
prof. PharmDr. Mgr. David Vetchý, Ph.D.
Department of Pharmaceutical Technology – Departments – Faculty of Pharmacy
Timetable
Mon 11:50–13:30 45-135
  • Timetable of Seminar Groups:
aF1FY1_13/01: Mon 16. 2. to Fri 13. 3. each even Tuesday 13:00–16:20 18-122, Mon 16. 3. to Fri 24. 4. each even Tuesday 13:00–13:50 18-122, each even Tuesday 13:50–16:20 18-107, Mon 27. 4. to Fri 8. 5. each even Tuesday 13:00–16:20 18-122, S. Pavloková
aF1FY1_13/02: Mon 16. 2. to Fri 13. 3. each even Tuesday 13:00–16:20 18-122, Mon 16. 3. to Fri 24. 4. each even Tuesday 13:00–13:50 18-122, each even Tuesday 13:50–16:20 18-138, Mon 27. 4. to Fri 8. 5. each even Tuesday 13:00–16:20 18-122, M. Bajerová, J. Halvová, S. Pavloková
aF1FY1_13/03: Mon 16. 2. to Fri 13. 3. each even Tuesday 16:30–19:50 18-122, Mon 16. 3. to Fri 24. 4. each even Tuesday 16:30–17:20 18-122, each even Tuesday 17:20–19:50 18-107, Mon 27. 4. to Fri 8. 5. each even Tuesday 16:30–19:50 18-122, S. Pavloková
aF1FY1_13/04: Mon 16. 2. to Fri 13. 3. each even Tuesday 16:30–19:50 18-122, Mon 16. 3. to Fri 24. 4. each even Tuesday 16:30–17:20 18-122, each even Tuesday 17:20–19:50 18-138, Mon 27. 4. to Fri 8. 5. each even Tuesday 16:30–19:50 18-122, J. Halvová, S. Pavloková
aF1FY1_13/05: Mon 16. 2. to Fri 13. 3. each odd Tuesday 13:00–16:20 18-122, Mon 16. 3. to Fri 24. 4. each odd Tuesday 13:00–13:50 18-122, each odd Tuesday 13:50–16:20 18-107, Mon 27. 4. to Fri 8. 5. each odd Tuesday 13:00–16:20 18-122, J. Zeman
aF1FY1_13/06: Mon 16. 2. to Fri 13. 3. each odd Tuesday 13:00–16:20 18-122, Mon 16. 3. to Fri 24. 4. each odd Tuesday 13:00–13:50 18-122, each odd Tuesday 13:50–16:20 18-138, Mon 27. 4. to Fri 8. 5. each odd Tuesday 13:00–16:20 18-122, S. Pavloková, J. Zeman
aF1FY1_13/07: Mon 16. 2. to Fri 13. 3. each odd Tuesday 16:30–19:50 18-122, Mon 16. 3. to Fri 24. 4. each odd Tuesday 16:30–17:20 18-122, each odd Tuesday 17:20–19:50 18-107, Mon 27. 4. to Fri 8. 5. each odd Tuesday 16:30–19:50 18-122, J. Halvová, S. Pavloková, J. Zeman
aF1FY1_13/08: Mon 16. 2. to Fri 13. 3. each odd Tuesday 16:30–19:50 18-122, Mon 16. 3. to Fri 24. 4. each odd Tuesday 16:30–17:20 18-122, each odd Tuesday 17:20–19:50 18-138, Mon 27. 4. to Fri 8. 5. each odd Tuesday 16:30–19:50 18-122, M. Bajerová, J. Halvová, S. Pavloková
aF1FY1_13/09: No timetable has been entered into IS.
Prerequisites (in Czech)
STUDIJNI_SKUPINA(nastup_2025)
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Abstract
The aim of the course is to provide students with fundamental knowledge of physical chemistry and colloid chemistry, which form part of the theoretical foundations essential for understanding processes applied in subsequent fields of study. Lectures focus on key areas of physical chemistry, in particular thermodynamics, chemical kinetics, solution behavior, electrochemistry, phase equilibria, interfacial phenomena, rheology, and colloidal systems. Seminars are intended for practicing methods of physical-chemical calculations, which are an integral part of mastering the discipline. Within laboratory classes, students practice essential basic experimental techniques of physical chemistry and learn to discuss and interpret the results obtained.
Learning outcomes
After completing the course, the student will be able to:
 – explain the thermodynamic basis of selected pharmaceutical processes;
 – characterize factors affecting the solubility and dissolution of substances;
 – determine and interpret kinetic parameters of pharmaceutical processes;
 – identify and summarize key features of electrochemical and phase phenomena;
 – apply rheological principles to practical problems;
 – identify and summarize essential characteristics of colloidal systems.
Key topics
  • LECTURES:
  • Thermodynamics.
  • Solubility: solubility gas/liquid, liquid/liquid, solid/liquid, solubility of salts, poor soluble electrolytes, weak electrolytes and their salts.
  • Electrochemistry.
  • Phase equilibria.
  • Phase interfaces.
  • Diffusion, dissolution and their importance in drug development.
  • Kinetics: rates and orders of reactions. Influence of temperature and other factors on reaction rates. The importance of kinetics in formulation and development of pharmaceuticals.
  • Rheology: Newtonian systems, non-Newtonian systems, thixotropy, determination of rheologic properties, viscoelasticity, application in pharmacy.
  • Colloids.

  • SEMINARS:
  • States of matter and thermodynamics – calculations.
  • Phase equilibria, chemical kinetics and electrochemistry – calculations.
  • Writtent test – calculations.

  • LABORATORY EXERCISES:
  • Density determination by pycnometric method.
  • Partitioning of succinic acid in the system butanol-water.
  • Measurement of surface tension using the stalagmometric method.
  • Writtent test – theory from laboratory exercises.
Study resources and literature
    recommended literature
  • HAMMES, Gordon G. and Sharon HAMMES-SCHIFFER. Physical chemistry for the biological sciences. Second edition. Hoboken, NJ: Wiley, 2015, 1 online. ISBN 9781118859148. URL info
  • ATKINS, P. W. and Julio DE PAULA. Fyzikální chemie. Vyd. 1. Praha: Vysoká škola chemicko-technologická v Praze, 2013, xxvi, 915. ISBN 9788070808306. info
  • Martin's physical pharmacy and pharmaceutical sciences : physical chemical and biopharmaceutical principles in the pharmaceutical sciences. Edited by Patrick J. Sinko - Yashveer Singh. Sixth edition. Philadelphia: Wolters Kluwer, 2011, viii, 659. ISBN 9781609134020. info
Approaches, practices, and methods used in teaching
Lectures, seminars and laboratory exercises.
Method of verifying learning outcomes and course completion requirements
Preparation of laboratory reports, continuous written tests, and a final written examination.
Language of instruction
Czech
Further Comments
Study Materials
  • Enrolment Statistics (recent)
  • Permalink: https://is.muni.cz/course/pharm/spring2026/aF1FY1_13