S1003 Structural and molecular biology of RNA

Faculty of Science
Autumn 2018
Extent and Intensity
2/0. 2 credit(s) (plus extra credits for completion). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
Teacher(s)
Mgr. PharmDr. Peter Lukavsky, Dr. rer. nat. (lecturer)
doc. Mgr. Richard Štefl, Ph.D. (lecturer)
doc. Mgr. Štěpánka Vaňáčová, Ph.D. (lecturer)
Supervisor
doc. Mgr. Richard Štefl, Ph.D.
National Centre for Biomolecular Research - Faculty of Science
Supplier department: National Centre for Biomolecular Research - Faculty of Science
Timetable
Mon 17. 9. to Fri 14. 12. Mon 13:00–14:50 A35-1S102
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
At the end of the course students should be able to understand the role of RNA in gene expression and its regulation. Multiple roles of RNA (catalytic, coding, regulatory, etc) will be discussed. In addition, the course will highlight advantages and various approaches that can be used to study the structural and molecular biology of RNA. This will provide a unique overview of modern techniques that may help students in their own research to choose the right technique to answer their scientific questions.
Syllabus
  • 1. structure, dynamics and chemistry of RNA 2. "RNA world" hypothesis 3. multiple roles of RNA in gene expression and its regulation 4. advanced biochemical and structural techniques for RNA studies
Literature
  • VOET, Donald and Judith G. VOET. Biochemistry. 3rd ed. Hoboken: John Wiley & Sons, 2004. xv, 1591. ISBN 0471392235. info
  • GESTELAND. The RNA World. Cold Spring Harbor Laboratory Press: Cold Spring Harbor Laboratory Press, 1999. 709 pp. second edition. ISBN 0-87969-589-7. info
  • The RNA world : the nature of modern RNA suggests a prebiotic RNA world. Edited by Raymond F. Gesteland - John F. Atkins. New York: Cold Spring Harbor Laboratory Press, 1993. xxiii, 630. ISBN 0-87969-456-4. info
Teaching methods
lectures & class discussions
Assessment methods
lectures, class discussion, oral exam
Language of instruction
English
Further Comments
Study Materials
The course can also be completed outside the examination period.
The course is taught annually.
The course is also listed under the following terms Autumn 2011 - acreditation, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2019.
  • Enrolment Statistics (Autumn 2018, recent)
  • Permalink: https://is.muni.cz/course/sci/autumn2018/S1003