C5150 Trends in Analytical Chemistry

Faculty of Science
Autumn 2023
Extent and Intensity
2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Taught in person.
Teacher(s)
prof. Mgr. Jan Preisler, Ph.D. (lecturer)
Guaranteed by
prof. Mgr. Jan Preisler, Ph.D.
Department of Chemistry – Chemistry Section – Faculty of Science
Supplier department: Department of Chemistry – Chemistry Section – Faculty of Science
Timetable
Wed 13:00–14:50 C14/207
Prerequisites
Passing courses Analytical chemistry I (C3100) and Analytical chemistry II (C4050).
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 9 fields of study the course is directly associated with, display
Course objectives
During the course consisting of lectures given by experts of the Institute of Analytical Chemistry of Academy of Sciences of the Czech Republic students will learn advanced analytical techniques. The course also involves a visit of the Institute of Analytical Chemistry of ASCR.
Learning outcomes
The course will widen students' knowledge of modern analytical chemistry. Students will visit a top scientific institution in the country.
Syllabus
  • Outline of the Trends in Analytical Chemistry course
  • The current outline with lecture dates can be found in the Study materials/Learning materials. Here are the lecture topics:
  • doc. RNDr. Michal Roth, CSc. Outline of the Trends in Analytical Chemistry course The current outline with lecture dates can be found in the Study materials/Learning materials. Here are the lecture topics:
  • doc. RNDr. Michal Roth, CSc. Compressed fluids in analytical separations. Supercritical fluids and compressed liquids – similarities and differences, applications in chromatography and sample preparation, supercritical fluid chromatography, supercritical fluid extraction, pressurized hot water extraction. Ionic liquids – motivation, properties, applications. Supercritical water as an agent to treat fused silica capillaries.
  • RNDr. Pavel Kubáň, Ph.D. DSc. Application of membrane-based preseparation methods in analysis of environmental, biological and clinical samples with particular focus on electrodriven techniques. New trends in treatment and preconcentration of complex samples, examples of off-line and on-line couplings with current analytical instruments, examples of practical solutions of real-world problems.
  • Mgr. Filip Duša, Ph.D. Analytical and preparative isoelectric focusing. Principles and variants of instrumental arrangement (capillary, gel, preparative channel, continuous methods), detection, internal standards – pI markers, applications in analysis of proteins and microorganisms, coupling to liquid chromatography and mass spectrometry. Current results – applications and focusing devices.
  • Mgr. Anna Týčová, Ph.D. Nanoparticles – origin of unique properties. Fabrication of nanoparticles. Nanoparticles in everyday life as well as in modern analytical research. Surface-enhanced Raman spectrometry (SERS).
  • RNDr. Pavel Mikuška, CSc. Atmospheric aerosols. Basic definitions and terms, effects of aerosols on environment and human health, physical properties, aerosol sources, size distribution and concentration measurements, chemical composition, specific types of aerosols (bioaerosols, nanoaerosols, indoor aerosols), aerosol concentrations in the Czech Republic.
  • Mgr. Antonín Hlaváček, Ph.D. Single-molecule methods in analytical chemistry. The counting of single molecules is introduced as a straightforward method for estimating the concentration of analytes. The properties of single-molecule methods are discussed. The focus is placed on the optical methods utilizing fluorescence and photon-upconversion.
  • doc. RNDr. Petr Kubáň, Ph.D. Analytical chemistry in point-of-care (POC) diagnostics. Definition of concepts, history, types of POC devices, examples. Indicator papers, lateral flow assays, paper-based microfluidics, portable analysers. Types of reactions, principles, detection. Example applications from our laboratory. New trends.
  • Ing. František Foret, DSc. Principles of microfabrications for analytical instrumentation. Coupling of microseparation techniques to mass spectrometry.
  • Mgr. Jakub Novotný, Ph.D. Acoustofluidics – acoustics in microfluidic applications. Interaction of soundwaves, liquid media and dispersed particles - basic principles. Acoustofluidic devices and instrumentation. Separation, sorting and trapping of microparticles and bioparticles in acoustic fields. Recent trends and applications.
  • prof. RNDr. Zbyněk Zdráhal, Dr. Proteomics. Basic definitions. Introduction to proteome complexity. Applications of mass spectrometry in proteomics. Future perspectives.
  • Mgr. Jana Lavická, Ph.D. Glycoproteomics. Analysis of protein glycosylation on the protein, peptide, and released glycan levels by capillary electrophoresis, liquid chromatography, and mass spectrometry.
  • Visit of labs in the Institute of Analytical Chemistry of the Czech Academy of Sciences, Veveří 967/97, 602 00 Brno.
Literature
  • Supplementary materials will be provided by the external lecturers
Teaching methods
Lectures and a visit of external workplace. The lectures are given in English.
Assessment methods
Final written examination
Language of instruction
English
Further Comments
Study Materials
The course is taught once in two years.
The course is also listed under the following terms Autumn 2010 - only for the accreditation, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, autumn 2021.
  • Enrolment Statistics (recent)
  • Permalink: https://is.muni.cz/course/sci/autumn2023/C5150