PřF:C7740 Organometallics - Course Information

C7740 Organometallics

Extent and Intensity

2/0/0. 2 credit(s) (plus extra credits for completion). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium), z (credit).
In-person direct teaching

Teacher(s)

prof. RNDr. Jiří Pinkas, Ph.D. (lecturer)
Mgr. Aleš Stýskalík, Ph.D. (lecturer)

Guaranteed by

prof. RNDr. Jiří Pinkas, Ph.D.
Department of Chemistry – Chemistry Section – Faculty of Science
Contact Person: prof. RNDr. Jiří Pinkas, Ph.D.
Supplier department: Department of Chemistry – Chemistry Section – Faculty of Science

Timetable

Wed 11:00–12:50 Kontaktujte učitele

Prerequisites

C1061 Inorganic Chemistry I
General Chemistry, Inorganic Chemistry I and II, Organic Chemistry

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

there are 6 fields of study the course is directly associated with, display

Abstract

The course aims to introduce undergraduates to the utility of organometallic chemistry, a discipline of importance to scientists and technologists in a variety of industry sectors. The main focus will be on the synthesis and reactivity of organometallic compounds of the main group and transition metals, supported by discussion of structure and bonding and their implications. The aim, on completion of the course, is that a student will be equipped to recognize the key classes of organometallic compounds, their methods of characterization, possible synthetic routes and anticipated reactivity.

Learning outcomes

The aim, on completion of the course, is that a student will be equipped to recognize the key classes of organometallic compounds, their methods of characterization, possible synthetic routes and anticipated reactivity.

Key topics

1. Historical development, general features of organometallic compounds and bonding types. General properties of organometallics, reactivity, and electron counting, ligand field theory.

 

2. Symmetry of molecules, spectroscopic characterization of organometallic compounds, NMR, IR, and MS.

 

3. Metal hydrides and dihydrogen complexes. Organometallics of groups 1 and 2 (organolithium, Gilman, and Grignard reagents). ⁶Li NMR spectra, isotope effects.

 

4. Organometallics of main-group metals. Organometallics of group 12 (organozinc and organomercury compounds). Organoboranes, organoborohydrides, boronic acids, tris(pentafluorophenyl)borane, frustrated Lewis pairs. Organometallics of group 13, organoaluminium compounds, trimethylaluminum, MAO. Organosilicon compounds, alkylhalogenosilanes, polysiloxanes, organotin, and organolead compounds, tetraethyl lead. Organometallics of group 15.

 

5. Metal alkyl complexes, sigma-alkyl-metal bonds, stability of alkyl complexes. Agostic bonds. Beta-H-elimination. Synthesis and reactivity of metal alkyl complexes.

 

6. Metal carbonyls, bonding in carbonyl complexes, spectroscopic properties. Synthesis and reactions of metal carbonyls. Fischer carbenes, Schrock alkylidenes. Synthesis, structure, and bonding. Spectroscopic characterization. Reactivity, alpha-H and beta-H elimination. N-heterocyclic carbenes
Phosphines, Tolman's parameters.

 

7. Transition metal p-complexes. Olefin, dialkene, alkyne, allyl complexes. Dewar-Chatt-Duncanson model. Structure, bonding, synthesis, and reactivity.

 

8. Cyclopentadienyl complexes, metallocenes, arene complexes. Ferrocene, structure, bonding. Synthesis and reactivity of metallocenes. Bent metallocenes, catalytic olefin polymerization, methylalumoxane co-catalyst.  

 

9. Principal reaction types in chemistry of transition metal organometallics: ligand substitution reactions, oxidative additions and reductive eliminations, insertions and deinsertions, reactions of coordinated ligands.

 

10. Introduction to homogeneous catalysis: conversion, selectivity, yield, turn-over-frequency, turn-over-number, enantiomeric enrichment, atom economy.

 

11. Utilization of transition metal organometallics in industrial catalysis: Hydroformylation, alkene hydrogenation, methanol carbonylation, alkenes polymerization.

 

12. Organometallic catalysis on laboratory scale: Asymmetric hydrogenation, C−H bond activation, C−C bond formation, hydrosilylation, nucleophilic and electrophilic additions and substitutions on the ligands.

Study resources and literature

recommended literature
• Atkins P.W. Shriver & Atkins Inorganic Chemistry. Oxford, 2010. info
• Housecroft, C. E., Sharpe, A. G. Anorganická Chemie. Praha, 2014. info
• CRABTREE, Robert H. The organometallic chemistry of the transition metals. Sixth edition. Hoboken, New Jersey: Wiley, 2014, xvi, 504. ISBN 9781118138076. info
• BOCHMANN, Manfred. Organometallics and catalysis : an introduction. Oxford: Oxford University Press, 2014, xviii, 410. ISBN 9780199668212. info
• HARTWIG, John F. Organotransition metal chemistry : from bonding to catalysis. Sausalito, Calif.: University Science Books, 2010, xxx, 1127. ISBN 9781891389535. info
• Hill A. F.: Organotransition Metal Chemistry, Royal Society of Chemistry, Cambridge 2001
• SPESSARD, Gary O. and Gary L. MIESSLER. Organometallic chemistry. Third edition. New York: Oxford University Press, 2016, xxiv, 763. ISBN 9780199342679. info

not specified
• Elschenbroich CH., Salzer A.: Organometallics, VCH Publishers, New York 1989
• Kašpárek F.: Přehled organosloučenin přechodných kovů, UP Olomouc 1994
• Kašpárek F.: Chemie organokových sloučenin, UP Olomouc 1991

Approaches, practices, and methods used in teaching

The course has a form of lectures.

Method of verifying learning outcomes and course completion requirements

The course has a form of lectures, written exam.

Language of instruction

Czech

Further Comments

Study Materials
The course is taught once in two years.

• Enrolment Statistics (recent)
  
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