C3705 Good laboratory practice in chemical laboratory

Faculty of Science
Spring 2021
Extent and Intensity
1/0/0. 1 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
RNDr. Marta Farková, CSc. (lecturer)
doc. Ing. Branislav Vrana, PhD. (lecturer)
Guaranteed by
RNDr. Marta Farková, CSc.
Department of Chemistry - Chemistry Section - Faculty of Science
Supplier department: Department of Chemistry - Chemistry Section - Faculty of Science
Prerequisites (in Czech)
! C3700 Quality in analytical laboratory && ! C5920 Good Laboratory Practice
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of the course is to acquaint students with GLP principles, relevant standards, organization of a laboratory and accreditation processes, with validations, evaluation of analyses results and sampling.
Learning outcomes
At the end of the course, students will be able to:
- understand major principle assuring quality of the results;
- discuss goals of GLP, fundamental terms and standards;
- describe, discuss and interpret organization of laboratory and work conditions, laboratory accreditation and proficiency testing;
- conduct equipment validation, validation of analytical system and methods;
- apply fundamentals of good sampling practice including techniques for homogeneous and nonhomogeneous objects, design and evaluation of sampling plan;
- process experimental data;
- understand needs of GLP application in practices.
  • 1. basic of statistics. 2. hypothesis testing, ANOVA. 3. chemical metrology. 4. calibration. 5. reference materials. 6. sampling. 7. uncertainties. 8. traceability in chemical measurement. 9. control charts.
  • SUCHÁNEK, Miroslav, Zbyněk PLZÁK, Pavel ŠUBRT and Ivan KORUNA. KVALIMETRIE 7. Validace analytických metod. Praha: EURACHEM-ČR, 1997. 137 pp. ISBN 80-901868-2-3. info
Teaching methods
Type of education: lectures, class discussion
Assessment methods
Type of exam: written and oral exam. 2 final written tests. Each comprises of 6 questions per 1 point. To pass the course, the student must reach the score of at least 4 points from each test.
Language of instruction
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2011 - only for the accreditation, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020.
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