PřF:C8885 Supramolecular Chemistry - Course Information
C8885 Supramolecular Chemistry
Faculty of ScienceSpring 2021
- Extent and Intensity
- 2/0/0. 2 credit(s) (fasci plus compl plus > 4). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
- Teacher(s)
- doc. RNDr. Ctibor Mazal, CSc. (lecturer)
- Guaranteed by
- doc. RNDr. Ctibor Mazal, CSc.
Department of Chemistry – Chemistry Section – Faculty of Science
Supplier department: Department of Chemistry – Chemistry Section – Faculty of Science - Timetable
- Mon 1. 3. to Fri 14. 5. Tue 10:00–11:50 online_CH4
- Course Enrolment Limitations
- The course is also offered to the students of the fields other than those the course is directly associated with.
- fields of study / plans the course is directly associated with
- Physical Chemistry (Eng.) (programme PřF, D-CH4)
- Physical Chemistry (programme PřF, D-CH4)
- Organic Chemistry (programme PřF, N-CH)
- Course objectives
- At the end of this course, students should be able to understand the basic concepts and principles of supramolecular chemistry. Main topics of the course can be summarized as follows: to understand the basic intermolecular interactions; to learn about typical compounds important in study of recognition of ions and neutral molecules; to demonstrate the basic principles of the supramolecular chemistry on reactivity and catalysis, transport processes, self-assembly processes, liquid crystals, as well as on design of supramolecular devices.
- Learning outcomes
- Student will be able to apply the knowledge about molecular recognition of cations, anions and neutral molecules, together with characterization of representative kinds of receptors; will be able to utilize basic methods of investigation of supramolecular phenomena and processes; to explain principles and function of some molecular and supramolecular devices.
- Syllabus
- 1. Concept of supramolecular chemistry. Basic principles. Weak intermolecular interactions (Coulombic, H-bond, cation-p interaction, p-p stacking, van der Waals interaction, hydrophobic effect).
- 2. Molecular recognition. Recognition and selectivity. Thermodynamic and kinetic selectivity. Molecular receptors. Chelate and macrocyclic effects. Pre-organization and complementarity. Recognition of cations, anions and neutral molecules.
- 3. Molecular recognition of cations. Crown ethers. Cryptands. Spherands. Binding of ammonium cations.
- 4. Calix[n]arenes. Structure and conformation. Simple chemical transformations. Complexation of cations, anions and neutral molecules.
- 5. Anion recognition. Bioreceptors of anions.
- 6. Recognition of neutral molecules. Inorganic and organic clathrates (Zeolites, urea, dianin etc.). Cyclodextrins.
- 7. Structure and stability of molecular complexes. Complexation constant. Complex stoichiometry determination.
- 8. Dendrimers. Synthesis and properties of dendrimers. Supramolecular applications.
- 9. Supramolecular synthesis, crystal engineering. Crystal growth. Design strategy.
- 10. Self-assembly processes (SA). Biochemical SA. SA in chemical synthesis. Catenanes and rotaxanes. Helicates. Programmed supramolecular syntheses.
- 11. Supramolecular reactivity and catalysis. Examples of catalytic systems. Biological mimics. Enzym models.
- 12. Supramolecular interactions in transport processes. Surfactants. Micelles, vesicles.
- 13. Supramolecular devices. Semiochemistry. Photonic devices. Electronic devices – switches, wires, semiconductors, rectifiers. NLO materials.
- 14. Liquid crystals. Structure and properties of LC. Selected applications.
- Literature
- LHOTÁK, Pavel and Ivan STIBOR. Molekulární design. Vyd. 1. Praha: Vydavatelství VŠCHT, 1997, [267] s. ISBN 80-7080-294-4. info
- Steed, Jonathan, W. - Atwood, Jerry L. Supramolecular Chemistry. Chichester: Wiley, 2000
- LEHN, Jean-Marie. Supermolecular chemistry :concepts and perspectives. Weinheim: VCH Verlagsgesellschaft, 1995, 271 s. ISBN 3-527-29311-6. info
- VÖGTLE, Fritz. Supramolecular chemistry : an introduction. Translated by Michel Grognuz. Chichester: John Wiley & Sons, 1991, viii, 337. ISBN 0471940615. info
- Teaching methods
- Lectures
- Assessment methods
- Oral or written exam.
- Language of instruction
- Czech
- Further Comments
- The course is taught annually.
- Enrolment Statistics (Spring 2021, recent)
- Permalink: https://is.muni.cz/course/sci/spring2021/C8885