aFAMB1_16 Microbiology for Pharmacists

Farmaceutická fakulta
jaro 2026

Předmět se v období jaro 2026 nevypisuje.

Rozsah
2/2/0. 28p+28c. 5 kr. Ukončení: zk.
Vyučující
PharmDr. Jakub Treml, Ph.D. (přednášející)
Ing. Marcela Nejezchlebová (cvičící)
Mgr. Bc. Daniela Nykodýmová, Ph.D. (cvičící)
PharmDr. Dominik Rotrekl, Ph.D. (cvičící)
PharmDr. Alice Sychrová, Ph.D. (cvičící)
PharmDr. Jakub Treml, Ph.D. (cvičící)
Garance
PharmDr. Jakub Treml, Ph.D.
Ústav molekulární farmacie – Ústavy – Farmaceutická fakulta
Omezení zápisu do předmětu
Předmět je určen pouze studentům mateřských oborů.
Mateřské obory/plány
Cíle předmětu
The subject provides an overview of pharmaceutical and medicinal aspects of microbiology, virology, mycology and parasitology. It brings basic information on the structure, function, genetics and taxonomy of medically important bacteria, viruses, fungi, yeast and parasites. The subject informs on Good Laboratory Practice and Good Manufacturing Practice. It focuses on basic methods of prevention, prophylaxis and treatment of infectious diseases and provides information on clinically significant infections in human medicine.
Výstupy z učení
Basic knowledge of microbiology forming the basis for follow-up subjects.
Osnova
Syllabus of the lectures
1. Introduction, information for the students. Structure of bacterial cells. Multiplication of bacteria, sporulation, germination.
2. Immunology.
3. Immunology and therapy, vaccination, biological therapy.
4. Bacteriology I.
5. Bacteriology II.
6. Antibacterial agents. Microbial resistance. Basics of rational therapy of infectious diseases.
7. Virology I.
8. Virology II.
9. Antiviral agents.
10. Basics of medical mycology.
11. Basics of medical parasitology.
12. Antiparasitic and antifungal agents.
13. Final test.

Syllabus of the seminaries
1. Safety precautions in microbiological laboratory, laboratory praxis, disinfection, sterilization.
2. Disinfecting and antiseptic substances. Cultivation media. Common microbiota of human body.
3. Diagnostic approaches I.: evaluation of colonies, staining and demonstration of selected bacteria, cultivation of bacteria, bacterial growth, identification and isolation of bacteria.
4. Diagnostic approaches II.: biochemical reactions, MALDI-TOF, McFarland standards for turbidity of bacterial suspensions, CFU-colony forming units, evaluation of bacterial concentration by cultivation, sensitivity testing, MIC, MBC, EUCAST.
5. Antisepsis in drug production, antimicrobial drug control.
6. Resistance and synergy of bacteria. Biofilm.
Practicals:
1. Preparation of cultivation media, evaluation of selected disinfection and antiseptic substances on microorganism of group 1.
2. Evaluation of effectivity of disinfecting substances, evaluation of bacterial colonies, Gram staining, isolation inoculation.
3. Assessment of microbial resistance, microdilution method (MIC), disc diffusion test (microorganism group 1).
4. Evaluation of the disc diffusion test and MIC, establishing of the MBC, establishing of the bacterial concentration in the specimen by cultivation (microorganisms group 1).
5. Evaluation of the MBC, determination of bacterial concentration in unknown specimen.
6. Final classification test.
Literatura
    doporučená literatura
  • MURRAY, Patrick R. Murray's basic medical microbiology. Second edition. Philadelphia, PA: Elsevier, 2024, ix, 292. ISBN 9780323878104. info
  • GOERING, Richard V.; Mark A. ZUCKERMAN; Hazel M. DOCKRELL a Peter L. CHIODINI. Mims' medical microbiology and immunology. Edited by Cedric A. Mims. Sixth edition. Edinburgh: Elsevier, 2019, xv, 552. ISBN 9780702071546. info
Výukové metody
Lectures and theoretical seminars that prepare for laboratory exercises. The output of the exercise are independently processed protocols.
Metody hodnocení
Written exam
Vyučovací jazyk
Angličtina
Informace učitele
To obtain the credit, students must fulfill the obligatory 100 % attendance of practices. To pass the exam, students must successfully write the classification test (min. 60 %) on the regular date. The correction tests will be written.
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