Mortality after surgery in Europe: a 7 day cohort study

J 2012

Mortality after surgery in Europe: a 7 day cohort study

PEARSE, Rupert M.; Rui P. MORENO; Peter BAUER; Paolo PELOSI; Philipp METNITZ et al.

Základní údaje

Originální název

Mortality after surgery in Europe: a 7 day cohort study

Název česky

Mortalita po chirurgických výkonech v Evropě: 7 denní kohortová studie

Autoři

Vydání

The Lancet, London, Elsevier, 2012, 0140-6736

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30200 3.2 Clinical medicine

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 39.060

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/12:00062797

Organizační jednotka

Lékařská fakulta

DOI

https://doi.org/10.1016/S0140-6736(12)61148-9

UT WoS

000308916400026

Klíčová slova česky

dlouhodobé přežití; nekardiochirugické výkony; zlepšení kvality perioperační péče;

Klíčová slova anglicky

SURGICAL QUALITY IMPROVEMENT; LONG-TERM SURVIVAL; NONCARDIAC SURGERY; CRITICAL-CARE; POSTOPERATIVE COMPLICATIONS; INPATIENT SURGERY; CANCER-SURGERY; MAJOR SURGERY; RISK; POPULATION

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 22. 7. 2013 09:47, Ing. Mgr. Věra Pospíšilíková

Anotace

V originále

Clinical outcomes after major surgery are poorly described at the national level. Evidence of heterogeneity between hospitals and health-care systems suggests potential to improve care for patients but this potential remains unconfirmed. The European Surgical Outcomes Study was an international study designed to assess outcomes after non-cardiac surgery in Europe. We did this 7 day cohort study between April 4 and April 11, 2011. We collected data describing consecutive patients aged 16 years and older undergoing inpatient non-cardiac surgery in 498 hospitals across 28 European nations. Patients were followed up for a maximum of 60 days. The primary endpoint was in-hospital mortality. Secondary outcome measures were duration of hospital stay and admission to critical care. We used Chi-square and Fisher's exact tests to compare categorical variables and the t test or the Mann-Whitney U test to compare continuous variables. Significance was set at <0.05. We constructed multilevel logistic regression models to adjust for the differences in mortality rates between countries. We included 46539 patients, of whom 1855 (4%) died before hospital discharge. 3599 (8%) patients were admitted to critical care after surgery with a median length of stay of 1.2 days (IQR 0.9–3.6). 1358 (73%) patients who died were not admitted to critical care at any stage after surgery. Crude mortality rates varied widely between countries (from 1.2% [95% CI 0.0–3.0] for Iceland to 21.5% [16.9–26.2] for Latvia). After adjustment for confounding variables, important differences remained between countries when compared with the UK, the country with the largest dataset (OR range from 0.44 [95% CI 0.19–1.05; p=0.06] for Finland to 6.92 [2.37–20.27; p=0.0004] for Poland).

Citovat

PEARSE, Rupert M.; Rui P. MORENO; Peter BAUER; Paolo PELOSI; Philipp METNITZ; Claudia SPIES; Benoit VALLET; Jean-Louis VINCENT; Andreas HOEFT; Andrew RHODES; Petr ŠTOURAČ; Katarína ZADRAŽILOVÁ; Kamil HUDÁČEK; Michal DRÁB; Barbora BĚLÍKOVÁ a Ivo KŘIKAVA. Mortality after surgery in Europe: a 7 day cohort study. The Lancet. London: Elsevier, 2012, roč. 380, č. 9847, s. 1059-1065. ISSN 0140-6736. Dostupné z: https://doi.org/10.1016/S0140-6736(12)61148-9.

@article{1081819,
   author = {Pearse, Rupert M. and Moreno, Rui P. and Bauer, Peter and Pelosi, Paolo and Metnitz, Philipp and Spies, Claudia and Vallet, Benoit and Vincent, JeanandLouis and Hoeft, Andreas and Rhodes, Andrew and Štourač, Petr and Zadražilová, Katarína and Hudáček, Kamil and Dráb, Michal and Bělíková, Barbora and Křikava, Ivo},
   article_location = {London},
   article_number = {9847},
   doi = {https://doi.org/10.1016/S0140-6736(12)61148-9},
   keywords = {SURGICAL QUALITY IMPROVEMENT; LONG-TERM SURVIVAL; NONCARDIAC SURGERY; CRITICAL-CARE; POSTOPERATIVE COMPLICATIONS; INPATIENT SURGERY; CANCER-SURGERY; MAJOR SURGERY; RISK; POPULATION},
   language = {eng},
   issn = {0140-6736},
   journal = {The Lancet},
   title = {Mortality after surgery in Europe: a 7 day cohort study},
   volume = {380},
   year = {2012}
}

TY  - JOUR
ID  - 1081819
AU  - Pearse, Rupert M. - Moreno, Rui P. - Bauer, Peter - Pelosi, Paolo - Metnitz, Philipp - Spies, Claudia - Vallet, Benoit - Vincent, Jean-Louis - Hoeft, Andreas - Rhodes, Andrew - Štourač, Petr - Zadražilová, Katarína - Hudáček, Kamil - Dráb, Michal - Bělíková, Barbora - Křikava, Ivo
PY  - 2012
TI  - Mortality after surgery in Europe: a 7 day cohort study
JF  - The Lancet
VL  - 380
IS  - 9847
SP  - 1059-1065
EP  - 1059-1065
PB  - Elsevier
SN  - 01406736
KW  - SURGICAL QUALITY IMPROVEMENT
KW  - LONG-TERM SURVIVAL
KW  - NONCARDIAC SURGERY
KW  - CRITICAL-CARE
KW  - POSTOPERATIVE COMPLICATIONS
KW  - INPATIENT SURGERY
KW  - CANCER-SURGERY
KW  - MAJOR SURGERY
KW  - RISK
KW  - POPULATION
N2  - Clinical outcomes after major surgery are poorly described at the national level. Evidence of heterogeneity between hospitals and health-care systems suggests potential to improve care for patients but this potential remains unconfirmed. The European Surgical Outcomes Study was an international study designed to assess outcomes after non-cardiac surgery in Europe. We did this 7 day cohort study between April 4 and April 11, 2011. We collected data describing consecutive patients aged 16 years and older undergoing inpatient non-cardiac surgery in 498 hospitals across 28 European nations. Patients were followed up for a maximum of 60 days. The primary endpoint was in-hospital mortality. Secondary outcome measures were duration of hospital stay and admission to critical care. We used Chi-square and Fisher's exact tests to compare categorical variables and the t test or the Mann-Whitney U test to compare continuous variables. Significance was set at <0.05. We constructed multilevel logistic regression models to adjust for the differences in mortality rates between countries. We included 46539 patients, of whom 1855 (4%) died before hospital discharge. 3599 (8%) patients were admitted to critical care after surgery with a median length of stay of 1.2 days (IQR 0.9–3.6). 1358 (73%) patients who died were not admitted to critical care at any stage after surgery. Crude mortality rates varied widely between countries (from 1.2% [95% CI 0.0–3.0] for Iceland to 21.5% [16.9–26.2] for Latvia). After adjustment for confounding variables, important differences remained between countries when compared with the UK, the country with the largest dataset (OR range from 0.44 [95% CI 0.19–1.05; p=0.06] for Finland to 6.92 [2.37–20.27; p=0.0004] for Poland).
ER  -

PEARSE, Rupert M.; Rui P. MORENO; Peter BAUER; Paolo PELOSI; Philipp METNITZ; Claudia SPIES; Benoit VALLET; Jean-Louis VINCENT; Andreas HOEFT; Andrew RHODES; Petr ŠTOURAČ; Katarína ZADRAŽILOVÁ; Kamil HUDÁČEK; Michal DRÁB; Barbora BĚLÍKOVÁ a Ivo KŘIKAVA. Mortality after surgery in Europe: a 7 day cohort study. \textit{The Lancet}. London: Elsevier, 2012, roč.~380, č.~9847, s.~1059-1065. ISSN~0140-6736. Dostupné z: https://doi.org/10.1016/S0140-6736(12)61148-9.

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