a 2012

The application of electron microscopy to the study of Toxoplasma gondii and Besnoitia besnoiti tachyzoites maintained in vitro

MELICHEROVÁ, Janka; Helena NEUMAYEROVÁ a Andrea VALIGUROVÁ

Základní údaje

Originální název

The application of electron microscopy to the study of Toxoplasma gondii and Besnoitia besnoiti tachyzoites maintained in vitro

Autoři

Vydání

Československá mikroskopická společnost MIKROSKOPIE 2012, 2012

Další údaje

Jazyk

angličtina

Typ výsledku

Konferenční abstrakt

Obor

10600 1.6 Biological sciences

Stát vydavatele

Slovensko

Utajení

není předmětem státního či obchodního tajemství

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/12:00058222

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova anglicky

tachyzoites; Besnoitia besnoiti; Toxoplasma gondii; ultrastructure;
Změněno: 17. 2. 2014 23:19, Mgr. Janka Melicherová

Anotace

V originále

Toxoplasma gondii and Besnoitia besnoiti are protozoan parasites belonging to the subfamily Toxoplasmatinae (Apicomplexa, Sarcocystidae). Even though these two pathogens are closely phylogenetically related, knowledge on their life cycle does not reach the same degree. While the life cycle and the transmission of important human parasite Toxoplasma gondii has been intensively studied for decades, Besnoitia besnoiti, endangering mainly cattle and thus causing significant economic looses, still remains enigmatic. In this study we focused on the morphology of tachyzoites and their interactions with host cell in vitro. Main aims include the comparison of morphological data on B. besnoiti with those on T. gondii as well as the standardization of electron microscopic techniques used for processing of unicellular parasites maintained on cell cultures. Tachyzoites of both species were maintained on MARC-145 cell lines (monkey kidney cell line) and then processed for scanning and transmission electron microscopy as well as for freeze etching procedure.

Česky

Toxoplasma gondii and Besnoitia besnoiti are protozoan parasites belonging to the subfamily Toxoplasmatinae (Apicomplexa, Sarcocystidae). Even though these two pathogens are closely phylogenetically related, knowledge on their life cycle does not reach the same degree. While the life cycle and the transmission of important human parasite Toxoplasma gondii has been intensively studied for decades, Besnoitia besnoiti, endangering mainly cattle and thus causing significant economic looses, still remains enigmatic. In this study we focused on the morphology of tachyzoites and their interactions with host cell in vitro. Main aims include the comparison of morphological data on B. besnoiti with those on T. gondii as well as the standardization of electron microscopic techniques used for processing of unicellular parasites maintained on cell cultures. Tachyzoites of both species were maintained on MARC-145 cell lines (monkey kidney cell line) and then processed for scanning and transmission electron microscopy as well as for freeze etching procedure.

Návaznosti

GPP506/10/P372, projekt VaV
Název: Srovnávací morfologie a imunohistochemie v hodnocení fylogenetických vztahů mezi zástupci raných linií kmene Apicomplexa
Investor: Grantová agentura ČR, Srovnávací morfologie a imunohistochemie v hodnocení fylogenetických vztahů mezi zástupci raných linií kmene Apicomplexa