Molecular Dynamics Simulations of RNA Molecules

C 2012

Molecular Dynamics Simulations of RNA Molecules

ŠPONER, Jiří, Michal OTYEPKA, Pavel BANÁŠ, Kamila RÉBLOVÁ, Nils WALTER et. al.

Základní údaje

Originální název

Molecular Dynamics Simulations of RNA Molecules

Autoři

ŠPONER, Jiří, Michal OTYEPKA, Pavel BANÁŠ, Kamila RÉBLOVÁ a Nils WALTER

Vydání

1. vydání. Cambridge, Innovations in Biomolecular Modeling and Simulations, od s. 129-155, 27 s. Volume 2, 2012

Nakladatel

The Royal Society of Chemistry

Další údaje

Jazyk

angličtina

Typ výsledku

Kapitola resp. kapitoly v odborné knize

Obor

10610 Biophysics

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Forma vydání

tištěná verze "print"

Organizační jednotka

Středoevropský technologický institut

ISBN

978-1-84973-462-2

Klíčová slova česky

Molecular dynamics, RNA, RNP

Štítky

ne MU

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 6. 4. 2016 14:04, Olga Křížová

Anotace

V originále

The central role of RNA in numerous biological processes including translation, protein localization, gene regulation, RNA processing, and viral replication calls for a detailed understanding of RNA function, structure, and conformational dynamics. Accompanying and enhancing our increasing appreciation of RNA is the rapidly expanding availability of high-resolution structures of RNAs and RNA-protein (RNP) complexes. These atomic resolution snapshots provide detailed rationalization for existing biochemical data. However, biological function depends on the dynamic evolution of structures along functional pathways. A complete understanding of the relevant structural dynamics exhibited by RNA requires monitoring timescales from picoseconds to hours through the application of a correspondingly broad range of techniques, with careful consideration given to the scope and limitation of each approach.

Návaznosti

LC06030, projekt VaV

Název: Biomolekulární centrum

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Biomolekulární centrum

Citovat

ŠPONER, Jiří, Michal OTYEPKA, Pavel BANÁŠ, Kamila RÉBLOVÁ a Nils WALTER. Molecular Dynamics Simulations of RNA Molecules. In Tamar Schlick. Innovations in Biomolecular Modeling and Simulations. 1. vydání. Cambridge: The Royal Society of Chemistry, 2012, s. 129-155. Volume 2. ISBN 978-1-84973-462-2.

@inbook{1089137,
   author = {Šponer, Jiří and Otyepka, Michal and Banáš, Pavel and Réblová, Kamila and Walter, Nils},
   address = {Cambridge},
   booktitle = {Innovations in Biomolecular Modeling and Simulations},
   edition = {1. vydání},
   editor = {Tamar Schlick},
   howpublished = {tištěná verze "print"},
   language = {eng},
   location = {Cambridge},
   isbn = {978-1-84973-462-2},
   pages = {129-155},
   publisher = {The Royal Society of Chemistry},
   title = {Molecular Dynamics Simulations of RNA Molecules},
   year = {2012}
}

TY  - CHAP
ID  - 1089137
AU  - Šponer, Jiří - Otyepka, Michal - Banáš, Pavel - Réblová, Kamila - Walter, Nils
PY  - 2012
TI  - Molecular Dynamics Simulations of RNA Molecules
VL  - Volume 2
PB  - The Royal Society of Chemistry
CY  - Cambridge
SN  - 9781849734622
N2  - The central role of RNA in numerous biological processes including translation, protein localization, gene regulation, RNA processing, and viral replication calls for a detailed understanding of RNA function, structure, and conformational dynamics. Accompanying and enhancing our increasing appreciation of RNA is the rapidly expanding availability of high-resolution structures of RNAs and RNA-protein (RNP) complexes. These atomic resolution snapshots provide detailed rationalization for existing biochemical data. However, biological function depends on the dynamic evolution of structures along functional pathways. A complete understanding of the relevant structural dynamics exhibited by RNA requires monitoring timescales from picoseconds to hours through the application of a correspondingly broad range of techniques, with careful consideration given to the scope and limitation of each approach.
ER  -

ŠPONER, Jiří, Michal OTYEPKA, Pavel BANÁŠ, Kamila RÉBLOVÁ a Nils WALTER. Molecular Dynamics Simulations of RNA Molecules. In Tamar Schlick. \textit{Innovations in Biomolecular Modeling and Simulations}. 1. vydání. Cambridge: The Royal Society of Chemistry, 2012, s.~129-155. Volume 2. ISBN~978-1-84973-462-2.

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