Default Mode Network and Extrastriate Visual Resting State
Network in Patients with Parkinson's Disease Dementia

J 2012

Default Mode Network and Extrastriate Visual Resting State Network in Patients with Parkinson's Disease Dementia

REKTOROVÁ, Irena; Lenka KRAJČOVIČOVÁ; Radek MAREČEK a Michal MIKL

Základní údaje

Originální název

Default Mode Network and Extrastriate Visual Resting State Network in Patients with Parkinson's Disease Dementia

Autoři

REKTOROVÁ, Irena; Lenka KRAJČOVIČOVÁ; Radek MAREČEK a Michal MIKL

Vydání

Neurodegenerative Diseases, Basel, Switzerland, Karger, 2012, 1660-2854

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.410

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14740/12:00064605

Organizační jednotka

Středoevropský technologický institut

DOI

https://doi.org/10.1159/000334765

UT WoS

000303660600049

Klíčová slova anglicky

Default mode network; Extrastriate visual resting state network; Parkinson's disease dementia; Functional connectivity

Štítky

ok, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 2. 4. 2013 08:51, Olga Křížová

Anotace

V originále

Aims: Using fMRI, we evaluated the default mode network (DMN) and the extrastriate visual resting state network (ESV-RSN) in 14 patients with Parkinson's disease dementia (PDD) as compared with 18 patients with Parkinson's disease (PD) without dementia and 18 healthy controls (HC). Methods: We analyzed the seed-based functional connectivity of both resting state data and deactivations during a visual complex scene-encoding task. Results: Using the posterior cingulate cortex/precuneus as a seed for the DMN analysis, we observed significant decreases of connectivity in the right inferior frontal gyrus in PDD as compared to PD and HC. Using the caudate nucleus as a seed for the ESV-RSN analysis, we found significant decreases of connectivity in the left and right inferior occipital gyrus in PDD as compared to HC. Conclusion: Differences in functional connectivity patterns between PDD and PD/HC were observed in areas known to be engaged in stimulus-driven reorienting of attention and in visual processing. Copyright (C) 2012 S. Karger AG, Basel

Návaznosti

MSM0021622404, záměr

Název: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Citovat

REKTOROVÁ, Irena; Lenka KRAJČOVIČOVÁ; Radek MAREČEK a Michal MIKL. Default Mode Network and Extrastriate Visual Resting State Network in Patients with Parkinson's Disease Dementia. Neurodegenerative Diseases. Basel, Switzerland: Karger, 2012, roč. 10, 1-4, s. 232-237. ISSN 1660-2854. Dostupné z: https://doi.org/10.1159/000334765.

@article{1094319,
   author = {Rektorová, Irena and Krajčovičová, Lenka and Mareček, Radek and Mikl, Michal},
   article_location = {Basel, Switzerland},
   article_number = {1-4},
   doi = {https://doi.org/10.1159/000334765},
   keywords = {Default mode network; Extrastriate visual resting state network; Parkinson's disease dementia; Functional connectivity},
   language = {eng},
   issn = {1660-2854},
   journal = {Neurodegenerative Diseases},
   title = {Default Mode Network and Extrastriate Visual Resting State Network in Patients with Parkinson's Disease Dementia},
   url = {http://www.karger.com/Article/Abstract/334765},
   volume = {10},
   year = {2012}
}

TY  - JOUR
ID  - 1094319
AU  - Rektorová, Irena - Krajčovičová, Lenka - Mareček, Radek - Mikl, Michal
PY  - 2012
TI  - Default Mode Network and Extrastriate Visual Resting State Network in Patients with Parkinson's Disease Dementia
JF  - Neurodegenerative Diseases
VL  - 10
IS  - 1-4
SP  - 232-237
EP  - 232-237
PB  - Karger
SN  - 16602854
KW  - Default mode network
KW  - Extrastriate visual resting state network
KW  - Parkinson's disease dementia
KW  - Functional connectivity
UR  - http://www.karger.com/Article/Abstract/334765
L2  - http://www.karger.com/Article/Abstract/334765
N2  - Aims: Using fMRI, we evaluated the default mode network (DMN) and the extrastriate visual resting state network (ESV-RSN) in 14 patients with Parkinson's disease dementia (PDD) as compared with 18 patients with Parkinson's disease (PD) without dementia and 18 healthy controls (HC). Methods: We analyzed the seed-based functional connectivity of both resting state data and deactivations during a visual complex scene-encoding task. Results: Using the posterior cingulate cortex/precuneus as a seed for the DMN analysis, we observed significant decreases of connectivity in the right inferior frontal gyrus in PDD as compared to PD and HC. Using the caudate nucleus as a seed for the ESV-RSN analysis, we found significant decreases of connectivity in the left and right inferior occipital gyrus in PDD as compared to HC. Conclusion: Differences in functional connectivity patterns between PDD and PD/HC were observed in areas known to be engaged in stimulus-driven reorienting of attention and in visual processing. Copyright (C) 2012 S. Karger AG, Basel
ER  -

REKTOROVÁ, Irena; Lenka KRAJČOVIČOVÁ; Radek MAREČEK a Michal MIKL. Default Mode Network and Extrastriate Visual Resting State Network in Patients with Parkinson's Disease Dementia. \textit{Neurodegenerative Diseases}. Basel, Switzerland: Karger, 2012, roč.~10, 1-4, s.~232-237. ISSN~1660-2854. Dostupné z: https://doi.org/10.1159/000334765.

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