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@article{1094319,
author = {Rektorová, Irena and Krajčovičová, Lenka and Mareček, Radek and Mikl, Michal},
article_location = {Basel, Switzerland},
article_number = {1-4},
doi = {http://dx.doi.org/10.1159/000334765},
keywords = {Default mode network; Extrastriate visual resting state network; Parkinson's disease dementia; Functional connectivity},
language = {eng},
issn = {1660-2854},
journal = {Neurodegenerative Diseases},
title = {Default Mode Network and Extrastriate Visual Resting State Network in Patients with Parkinson's Disease Dementia},
url = {http://www.karger.com/Article/Abstract/334765},
volume = {10},
year = {2012}
}
TY - JOUR
ID - 1094319
AU - Rektorová, Irena - Krajčovičová, Lenka - Mareček, Radek - Mikl, Michal
PY - 2012
TI - Default Mode Network and Extrastriate Visual Resting State Network in Patients with Parkinson's Disease Dementia
JF - Neurodegenerative Diseases
VL - 10
IS - 1-4
SP - 232-237
EP - 232-237
PB - Karger
SN - 16602854
KW - Default mode network
KW - Extrastriate visual resting state network
KW - Parkinson's disease dementia
KW - Functional connectivity
UR - http://www.karger.com/Article/Abstract/334765
L2 - http://www.karger.com/Article/Abstract/334765
N2 - Aims: Using fMRI, we evaluated the default mode network (DMN) and the extrastriate visual resting state network (ESV-RSN) in 14 patients with Parkinson's disease dementia (PDD) as compared with 18 patients with Parkinson's disease (PD) without dementia and 18 healthy controls (HC). Methods: We analyzed the seed-based functional connectivity of both resting state data and deactivations during a visual complex scene-encoding task. Results: Using the posterior cingulate cortex/precuneus as a seed for the DMN analysis, we observed significant decreases of connectivity in the right inferior frontal gyrus in PDD as compared to PD and HC. Using the caudate nucleus as a seed for the ESV-RSN analysis, we found significant decreases of connectivity in the left and right inferior occipital gyrus in PDD as compared to HC. Conclusion: Differences in functional connectivity patterns between PDD and PD/HC were observed in areas known to be engaged in stimulus-driven reorienting of attention and in visual processing. Copyright (C) 2012 S. Karger AG, Basel
ER -
REKTOROVÁ, Irena, Lenka KRAJČOVIČOVÁ, Radek MAREČEK a Michal MIKL. Default Mode Network and Extrastriate Visual Resting State Network in Patients with Parkinson's Disease Dementia. \textit{Neurodegenerative Diseases}. Basel, Switzerland: Karger, roč.~10, 1-4, s.~232-237. ISSN~1660-2854. doi:10.1159/000334765. 2012.
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