J 2014

Percutaneous Intraductal Radiofrequency Ablation for Clearance of Occluded Metal Stent in Malignant Biliary Obstruction: Feasibility and Early Results

PAI, Madhava; Vlastimil VÁLEK; Tomáš ANDRAŠINA; Attila DOROS; Pietro QUARETTI et al.

Základní údaje

Originální název

Percutaneous Intraductal Radiofrequency Ablation for Clearance of Occluded Metal Stent in Malignant Biliary Obstruction: Feasibility and Early Results

Autoři

PAI, Madhava; Vlastimil VÁLEK ORCID; Tomáš ANDRAŠINA; Attila DOROS; Pietro QUARETTI; Rita GOLFIERI; Cristina MOSCONI a Habib NAGY

Vydání

CardioVascular and Interventional Radiology, New York, Springer-Verlag, 2014, 0174-1551

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Impakt faktor

Impact factor: 2.071

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/14:00074725

Organizační jednotka

Lékařská fakulta

EID Scopus

Klíčová slova anglicky

Bile duct/gallbladder/biliary; Cancer; Interventional oncology; Liver/hepatic; Pancreas; Radiofrequency ablation; Stenosis/restenosis; Tumour/neoplasm

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 24. 4. 2015 12:35, Soňa Böhmová

Anotace

V originále

Purpose: The major complication occurring with biliary stents is stent occlusion, frequently seen because of tumour in-growth, epithelial hyperplasia, and sludge deposits, resulting in recurrent jaundice and cholangitis. We report a prospective study with the results of first in man percutaneous intraductal radiofrequency (RF) ablation to clear the blocked metal stents in patients with malignant biliary obstruction using a novel bipolar RF catheter. Methods: Nine patients with malignant biliary obstruction and blocked metal stents were included. These patients underwent intraductal biliary RF ablation through the blocked metal stent following external biliary decompression with an internal-external biliary drainage. Results: All nine patients had their stent patency restored successfully without the use of secondary stents. Following this intervention, there was no 30-day mortality, haemorrhage, bile duct perforation, bile leak, or pancreatitis. Of the nine patients, six are alive and three patients are dead with a median follow-up of 122 (range 50-488) days and a median stent patency of 102.5 (range 50-321) days. Six patients had their stent patent at the time of last follow-up or death. Three patients with stent blockage at 321, 290, and 65 days postprocedure underwent percutaneous transhepatic drain insertion and repeat ablation. Conclusions: In this selective group of patients, it appears that this new approach is safe and feasible. Efficacy remains to be proven in future, randomized, prospective studies.