Pseudohyperkalaemia in leukaemic patients: the effect of test
tube type and form of transport to the laboratory

J 2014

Pseudohyperkalaemia in leukaemic patients: the effect of test tube type and form of transport to the laboratory

DASTYCH, Milan a Zdeňka ČERMÁKOVÁ

Základní údaje

Originální název

Pseudohyperkalaemia in leukaemic patients: the effect of test tube type and form of transport to the laboratory

Autoři

DASTYCH, Milan (203 Česká republika, garant, domácí) a Zdeňka ČERMÁKOVÁ (203 Česká republika, domácí)

Vydání

Annals of Clinical Biochemistry, THOUSAND OAKS, SAGE PUBLICATIONS INC, 2014, 0004-5632

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10600 1.6 Biological sciences

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 2.335

Kód RIV

RIV/00216224:14110/14:00074777

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1177/0004563213497928

UT WoS

000339625900014

Klíčová slova anglicky

Leukaemia; clinical studies; electrolytes; analytes

Štítky

EL OK

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 24. 4. 2015 12:34, Soňa Böhmová

Anotace

V originále

Background The present study was aimed at determining the effect of the tube type used for primary sample collection and the manner of transport prior to assessment (either manual or by pneumatic tube) on the degree of pseudohyperkalaemia in leukaemic patients. Methods Blood from six leukaemic patients was collected into seven primary sample tubes (Monovette, Sarstedt): sample A, heparinized blood gas syringe (potassium reference value); sample B, plasma Li-heparin without separator gel; sample C, plasma Li-heparin with separator gel; and sample D, serum with separator gel. The primary sample tubes designated B, C and D were transported to the laboratory manually. Duplicates of the same sample tubes, BPT, CPT and DPT, were sent to the laboratory by pneumatic tube. Results In patients with chronic lymphocytic leukaemia (CLL), there was no increase in the concentration of potassium in samples B, C and D when compared to the reference value. Transport of the samples by pneumatic tube led to a pronounced increase in potassium concentration in samples BPT and CPT, whereas there was no increase in sample DPT when compared to the reference value. In the patient with chronic myeloid leukaemia (CML), an increase in potassium concentration occurred in sample D and in samples BPT, CPT and DPT. A similar finding was observed in the patient with acute lymphocytic leukaemia (ALL), furthermore with an extremely high concentration of potassium in samples C and CPT. Conclusions Manual transport of non-coagulable blood (plasma Li-heparin without separator gel) to the laboratory results in the least possible artificial increase in potassium concentration in the sample.

Citovat

DASTYCH, Milan a Zdeňka ČERMÁKOVÁ. Pseudohyperkalaemia in leukaemic patients: the effect of test tube type and form of transport to the laboratory. Annals of Clinical Biochemistry. THOUSAND OAKS: SAGE PUBLICATIONS INC, 2014, roč. 51, č. 1, s. 110-113. ISSN 0004-5632. Dostupné z: https://dx.doi.org/10.1177/0004563213497928.

@article{1126220,
   author = {Dastych, Milan and Čermáková, Zdeňka},
   article_location = {THOUSAND OAKS},
   article_number = {1},
   doi = {http://dx.doi.org/10.1177/0004563213497928},
   keywords = {Leukaemia; clinical studies; electrolytes; analytes},
   language = {eng},
   issn = {0004-5632},
   journal = {Annals of Clinical Biochemistry},
   title = {Pseudohyperkalaemia in leukaemic patients: the effect of test tube type and form of transport to the laboratory},
   volume = {51},
   year = {2014}
}

TY  - JOUR
ID  - 1126220
AU  - Dastych, Milan - Čermáková, Zdeňka
PY  - 2014
TI  - Pseudohyperkalaemia in leukaemic patients: the effect of test tube type and form of transport to the laboratory
JF  - Annals of Clinical Biochemistry
VL  - 51
IS  - 1
SP  - 110-113
EP  - 110-113
PB  - SAGE PUBLICATIONS INC
SN  - 00045632
KW  - Leukaemia
KW  - clinical studies
KW  - electrolytes
KW  - analytes
N2  - Background The present study was aimed at determining the effect of the tube type used for primary sample collection and the manner of transport prior to assessment (either manual or by pneumatic tube) on the degree of pseudohyperkalaemia in leukaemic patients. Methods Blood from six leukaemic patients was collected into seven primary sample tubes (Monovette, Sarstedt): sample A, heparinized blood gas syringe (potassium reference value); sample B, plasma Li-heparin without separator gel; sample C, plasma Li-heparin with separator gel; and sample D, serum with separator gel. The primary sample tubes designated B, C and D were transported to the laboratory manually. Duplicates of the same sample tubes, BPT, CPT and DPT, were sent to the laboratory by pneumatic tube. Results In patients with chronic lymphocytic leukaemia (CLL), there was no increase in the concentration of potassium in samples B, C and D when compared to the reference value. Transport of the samples by pneumatic tube led to a pronounced increase in potassium concentration in samples BPT and CPT, whereas there was no increase in sample DPT when compared to the reference value. In the patient with chronic myeloid leukaemia (CML), an increase in potassium concentration occurred in sample D and in samples BPT, CPT and DPT. A similar finding was observed in the patient with acute lymphocytic leukaemia (ALL), furthermore with an extremely high concentration of potassium in samples C and CPT. Conclusions Manual transport of non-coagulable blood (plasma Li-heparin without separator gel) to the laboratory results in the least possible artificial increase in potassium concentration in the sample.
ER  -

DASTYCH, Milan a Zdeňka ČERMÁKOVÁ. Pseudohyperkalaemia in leukaemic patients: the effect of test tube type and form of transport to the laboratory. \textit{Annals of Clinical Biochemistry}. THOUSAND OAKS: SAGE PUBLICATIONS INC, 2014, roč.~51, č.~1, s.~110-113. ISSN~0004-5632. Dostupné z: https://dx.doi.org/10.1177/0004563213497928.

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