Benefits and pitfalls of cardiovascular medication in seniors

J 2013

Benefits and pitfalls of cardiovascular medication in seniors

MATĚJOVSKÁ KUBEŠOVÁ, Hana; Pavel WEBER; Hana MELUZÍNOVÁ; Katarína BIELAKOVÁ; Jan MATEJOVSKY et. al.

Základní údaje

Originální název

Benefits and pitfalls of cardiovascular medication in seniors

Autoři

MATĚJOVSKÁ KUBEŠOVÁ, Hana (203 Česká republika, garant, domácí); Pavel WEBER (203 Česká republika, domácí); Hana MELUZÍNOVÁ (203 Česká republika, domácí); Katarína BIELAKOVÁ (703 Slovensko, domácí) a Jan MATEJOVSKY (203 Česká republika)

Vydání

Wiener klinische Wochenschrift, Vídeň, SPRINGER WIEN, 2013, 0043-5325

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Rakousko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 0.791

Kód RIV

RIV/00216224:14110/13:00069849

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1007/s00508-013-0395-2

UT WoS

000323670700001

Klíčová slova anglicky

Angiotensin converting enzyme inhibitors; Antiaggregants; beta-blockers; Statins; Calcium blockers; Diuretics; Digoxin; Pharmacotherapy in the elderly; Unwanted side effects; Medical interactions

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 22. 10. 2013 17:59, Soňa Böhmová

Anotace

V originále

Authors analyze actual situation in treatment of cardiovascular diseases in older patients. Different groups of recommended drugs are discussed separately; possible risks for elderly patients are stressed. Angiotensin converting enzyme inhibitors-this group is widely used in older patients because of their hypotensive effect, positive influence on cardiac failure, and positive modulation of endothelial dysfunction. The risk of hyperkalemia must be considered. Antiaggregants and anticoagulants are proved as potent prophylactic treatment, but the associated risk of gastrointestinal bleeding must be weighed very carefully. Bradycardia related to beta-blockers, especially in combination with other medications lowering the heart rate must be taken into account. Otherwise, this group brings the highest profit in cardiovascular diseases as for morbidity and mortality. Attention is paid to calcium channel blockers, statins, diuretics, nitrates, and digoxin. A table listing the possible side effects and clinical symptoms of overdose by medications most frequently used in the elderly concludes the article.

Citovat

MATĚJOVSKÁ KUBEŠOVÁ, Hana; Pavel WEBER; Hana MELUZÍNOVÁ; Katarína BIELAKOVÁ a Jan MATEJOVSKY. Benefits and pitfalls of cardiovascular medication in seniors. Wiener klinische Wochenschrift. Vídeň: SPRINGER WIEN, 2013, roč. 125, 15-16, s. 425-436. ISSN 0043-5325. Dostupné z: https://dx.doi.org/10.1007/s00508-013-0395-2.

@article{1126906,
   author = {Matějovská Kubešová, Hana and Weber, Pavel and Meluzínová, Hana and Bielaková, Katarína and Matejovsky, Jan},
   article_location = {Vídeň},
   article_number = {15-16},
   doi = {http://dx.doi.org/10.1007/s00508-013-0395-2},
   keywords = {Angiotensin converting enzyme inhibitors; Antiaggregants; beta-blockers; Statins; Calcium blockers; Diuretics; Digoxin; Pharmacotherapy in the elderly; Unwanted side effects; Medical interactions},
   language = {eng},
   issn = {0043-5325},
   journal = {Wiener klinische Wochenschrift},
   title = {Benefits and pitfalls of cardiovascular medication in seniors},
   volume = {125},
   year = {2013}
}

TY  - JOUR
ID  - 1126906
AU  - Matějovská Kubešová, Hana - Weber, Pavel - Meluzínová, Hana - Bielaková, Katarína - Matejovsky, Jan
PY  - 2013
TI  - Benefits and pitfalls of cardiovascular medication in seniors
JF  - Wiener klinische Wochenschrift
VL  - 125
IS  - 15-16
SP  - 425-436
EP  - 425-436
PB  - SPRINGER WIEN
SN  - 00435325
KW  - Angiotensin converting enzyme inhibitors
KW  - Antiaggregants
KW  - beta-blockers
KW  - Statins
KW  - Calcium blockers
KW  - Diuretics
KW  - Digoxin
KW  - Pharmacotherapy in the elderly
KW  - Unwanted side effects
KW  - Medical interactions
N2  - Authors analyze actual situation in treatment of cardiovascular diseases in older patients. Different groups of recommended drugs are discussed separately; possible risks for elderly patients are stressed. Angiotensin converting enzyme inhibitors-this group is widely used in older patients because of their hypotensive effect, positive influence on cardiac failure, and positive modulation of endothelial dysfunction. The risk of hyperkalemia must be considered. Antiaggregants and anticoagulants are proved as potent prophylactic treatment, but the associated risk of gastrointestinal bleeding must be weighed very carefully. Bradycardia related to beta-blockers, especially in combination with other medications lowering the heart rate must be taken into account. Otherwise, this group brings the highest profit in cardiovascular diseases as for morbidity and mortality. Attention is paid to calcium channel blockers, statins, diuretics, nitrates, and digoxin. A table listing the possible side effects and clinical symptoms of overdose by medications most frequently used in the elderly concludes the article.
ER  -

MATĚJOVSKÁ KUBEŠOVÁ, Hana; Pavel WEBER; Hana MELUZÍNOVÁ; Katarína BIELAKOVÁ a Jan MATEJOVSKY. Benefits and pitfalls of cardiovascular medication in seniors. \textit{Wiener klinische Wochenschrift}. Vídeň: SPRINGER WIEN, 2013, roč.~125, 15-16, s.~425-436. ISSN~0043-5325. Dostupné z: https://dx.doi.org/10.1007/s00508-013-0395-2.

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