Quality of life after transcatheter aortic valve implantation
and surgical replacement in high-risk elderly patients

J 2013

Quality of life after transcatheter aortic valve implantation and surgical replacement in high-risk elderly patients

KALA, Petr; Martin TRETINA; Martin POLOCZEK; Jiri ONDRASEK; Petr MALIK et al.

Základní údaje

Originální název

Quality of life after transcatheter aortic valve implantation and surgical replacement in high-risk elderly patients

Autoři

KALA, Petr; Martin TRETINA; Martin POLOCZEK; Jiri ONDRASEK; Petr MALIK; Petr POKORNY; Jiří PAŘENICA; Jindřich ŠPINAR; Jiří JARKOVSKÝ ; Simona LITTNEROVÁ a Petr NEMEC

Vydání

Biomedical Papers of the Faculty of Medicine of Palacký University, Olomouc, Czech Republic, Olomouc, Palacký University, 2013, 1213-8118

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 1.661

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/13:00070304

Organizační jednotka

Lékařská fakulta

DOI

https://doi.org/10.5507/bp.2012.062

UT WoS

000316989100013

Klíčová slova anglicky

quality of life; EQ-5D; aortic replacement; aortic valve implantation; TAVI; bioprosthesis

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 13. 4. 2014 12:20, Ing. Mgr. Věra Pospíšilíková

Anotace

V originále

Aim. The aim of this study was to compare the quality of life after transcatheter aortic valve implantation (TAVI) and surgical replacement (SAVR) at one year. Methods. The study included 45 consecutive high-risk patients (average age 82.0 years; logistic Euroscore 22.3%) with symptomatic severe aortic stenosis allocated to TAVI transfemoral, TAVI transapical using the Edwards-Sapien valve or SAVR with the Edwards Perimount bioprosthesis (n= 15 in each). The pre-operative characteristics were similar except for more myocardial infarctions in TAVI. The quality of life was assessed using the standardized EQ-5D questionnaire at baseline and on days 30, 90 and 360. The protocol was approved by the local ethics committee and an informed consent was signed. A total of 7 patients (15.5%) died during follow-up. Results. At baseline no significant differences in any of the quality-of-life parameters were found except for usual activities described as "best" (46.7% in SAVR vs. 10.0% in TAVI; P=0.002). At 30 and 90 days surviving patients were similar and at 360 days only the anxiety/depression score was "best" in 83.3% SAVR vs. 59.1% (P=0.046). Functional status improved in all patients (NYHA class I-II in 13.3% at baseline vs. 78.9% at 360-days) and the general health median significantly improved in TAVI patients (from 50 to 67; P=0.001) with a positive trend in SAVR patients (P=0.060). Conclusions. At one year, the general quality of life of high-risk patients had significantly improved after transcatheter aortic valve implantation with a positive trend in surgically treated patients.

Citovat

KALA, Petr; Martin TRETINA; Martin POLOCZEK; Jiri ONDRASEK; Petr MALIK; Petr POKORNY; Jiří PAŘENICA; Jindřich ŠPINAR; Jiří JARKOVSKÝ; Simona LITTNEROVÁ a Petr NEMEC. Quality of life after transcatheter aortic valve implantation and surgical replacement in high-risk elderly patients. Biomedical Papers of the Faculty of Medicine of Palacký University, Olomouc, Czech Republic. Olomouc: Palacký University, 2013, roč. 157, č. 1, s. 75-80. ISSN 1213-8118. Dostupné z: https://doi.org/10.5507/bp.2012.062.

@article{1131178,
   author = {Kala, Petr and Tretina, Martin and Poloczek, Martin and Ondrasek, Jiri and Malik, Petr and Pokorny, Petr and Pařenica, Jiří and Špinar, Jindřich and Jarkovský, Jiří and Littnerová, Simona and Nemec, Petr},
   article_location = {Olomouc},
   article_number = {1},
   doi = {https://doi.org/10.5507/bp.2012.062},
   keywords = {quality of life; EQ-5D; aortic replacement; aortic valve implantation; TAVI; bioprosthesis},
   language = {eng},
   issn = {1213-8118},
   journal = {Biomedical Papers of the Faculty of Medicine of Palacký University, Olomouc, Czech Republic},
   title = {Quality of life after transcatheter aortic valve implantation and surgical replacement in high-risk elderly patients},
   volume = {157},
   year = {2013}
}

TY  - JOUR
ID  - 1131178
AU  - Kala, Petr - Tretina, Martin - Poloczek, Martin - Ondrasek, Jiri - Malik, Petr - Pokorny, Petr - Pařenica, Jiří - Špinar, Jindřich - Jarkovský, Jiří - Littnerová, Simona - Nemec, Petr
PY  - 2013
TI  - Quality of life after transcatheter aortic valve implantation and surgical replacement in high-risk elderly patients
JF  - Biomedical Papers of the Faculty of Medicine of Palacký University, Olomouc, Czech Republic
VL  - 157
IS  - 1
SP  - 75-80
EP  - 75-80
PB  - Palacký University
SN  - 12138118
KW  - quality of life
KW  - EQ-5D
KW  - aortic replacement
KW  - aortic valve implantation
KW  - TAVI
KW  - bioprosthesis
N2  - Aim. The aim of this study was to compare the quality of life after transcatheter aortic valve implantation (TAVI) and surgical replacement (SAVR) at one year. Methods. The study included 45 consecutive high-risk patients (average age 82.0 years; logistic Euroscore 22.3%) with symptomatic severe aortic stenosis allocated to TAVI transfemoral, TAVI transapical using the Edwards-Sapien valve or SAVR with the Edwards Perimount bioprosthesis (n= 15 in each). The pre-operative characteristics were similar except for more myocardial infarctions in TAVI. The quality of life was assessed using the standardized EQ-5D questionnaire at baseline and on days 30, 90 and 360. The protocol was approved by the local ethics committee and an informed consent was signed. A total of 7 patients (15.5%) died during follow-up. Results. At baseline no significant differences in any of the quality-of-life parameters were found except for usual activities described as "best" (46.7% in SAVR vs. 10.0% in TAVI; P=0.002). At 30 and 90 days surviving patients were similar and at 360 days only the anxiety/depression score was "best" in 83.3% SAVR vs. 59.1% (P=0.046). Functional status improved in all patients (NYHA class I-II in 13.3% at baseline vs. 78.9% at 360-days) and the general health median significantly improved in TAVI patients (from 50 to 67; P=0.001) with a positive trend in SAVR patients (P=0.060). Conclusions. At one year, the general quality of life of high-risk patients had significantly improved after transcatheter aortic valve implantation with a positive trend in surgically treated patients.
ER  -

KALA, Petr; Martin TRETINA; Martin POLOCZEK; Jiri ONDRASEK; Petr MALIK; Petr POKORNY; Jiří PAŘENICA; Jindřich ŠPINAR; Jiří JARKOVSKÝ; Simona LITTNEROVÁ a Petr NEMEC. Quality of life after transcatheter aortic valve implantation and surgical replacement in high-risk elderly patients. \textit{Biomedical Papers of the Faculty of Medicine of Palacký University, Olomouc, Czech Republic}. Olomouc: Palacký University, 2013, roč.~157, č.~1, s.~75-80. ISSN~1213-8118. Dostupné z: https://doi.org/10.5507/bp.2012.062.

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