J 2014

Sperm cryopreservation before testicular cancer treatment and its subsequent utilization for the treatment of infertility.

ŽÁKOVÁ, Jana; Eva LOUSOVÁ; Pavel VENTRUBA; Igor CRHA; Hana POCHOPOVÁ et al.

Základní údaje

Originální název

Sperm cryopreservation before testicular cancer treatment and its subsequent utilization for the treatment of infertility.

Název česky

Kryokonzervace spermatu před léčbou karcinomu varlat a jeho následné použití v léčbě infertlity

Autoři

ŽÁKOVÁ, Jana; Eva LOUSOVÁ; Pavel VENTRUBA; Igor CRHA; Hana POCHOPOVÁ; Eva TESAŘOVÁ; Jaroslava VINKLÁRKOVÁ a Mohamed Ismail Abdo NUSSIR

Vydání

The Scientific World Journal, New York, Hindawi Publishing Corporation, 2014, 1537-744X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30214 Obstetrics and gynaecology

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 1.219 v roce 2013

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/14:00074873

Organizační jednotka

Lékařská fakulta

EID Scopus

Klíčová slova česky

kryokonzervace spermií karcinom varlat léčba infertility

Klíčová slova anglicky

sperm cryopreservation testicular cancer infertility treatment

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 3. 2. 2015 11:43, Ing. Mgr. Věra Pospíšilíková

Anotace

V originále

Aims. In this study we report our results with storage of cryopreserved semen intended for preservation and subsequent infertility treatment in men with testicular cancer during the last 18 years. Methods. Cryopreserved semen of 523 men with testicular cancer was collected between October 1995 and the end of December 2012. Semen of 34 men (6.5%) was used for fertilization of their partners. They underwent 57 treatment cycles with cryopreserved, fresh, and/or donor sperm. Results. A total of 557 men have decided to freeze their semen before cancer treatment. Azoospermia was diagnosed in 34 men (6.1%), and semen was cryopreserved in 532 patients. Seminoma was diagnosed in 283 men (54.1%) and nonseminomatous germ cell tumors in 240 men (45.9%). 34 patients who returned for infertility treatment underwent 46 treatment cycles with cryopreserved sperm. Totally 16 pregnancies were achieved, that is, 34.8% pregnancy rate. Conclusion. The testicular cancer survivors have a good chance of fathering a child by using sperm cryopreserved prior to the oncology treatment, even when it contains only limited number of spermatozoa.