2014
Sperm cryopreservation before testicular cancer treatment and its subsequent utilization for the treatment of infertility.
ŽÁKOVÁ, Jana; Eva LOUSOVÁ; Pavel VENTRUBA; Igor CRHA; Hana POCHOPOVÁ et al.Základní údaje
Originální název
Sperm cryopreservation before testicular cancer treatment and its subsequent utilization for the treatment of infertility.
Název česky
Kryokonzervace spermatu před léčbou karcinomu varlat a jeho následné použití v léčbě infertlity
Autoři
ŽÁKOVÁ, Jana; Eva LOUSOVÁ; Pavel VENTRUBA; Igor CRHA; Hana POCHOPOVÁ; Eva TESAŘOVÁ; Jaroslava VINKLÁRKOVÁ a Mohamed Ismail Abdo NUSSIR
Vydání
The Scientific World Journal, New York, Hindawi Publishing Corporation, 2014, 1537-744X
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
30214 Obstetrics and gynaecology
Stát vydavatele
Spojené státy
Utajení
není předmětem státního či obchodního tajemství
Impakt faktor
Impact factor: 1.219 v roce 2013
Označené pro přenos do RIV
Ano
Kód RIV
RIV/00216224:14110/14:00074873
Organizační jednotka
Lékařská fakulta
UT WoS
EID Scopus
Klíčová slova česky
kryokonzervace spermií karcinom varlat léčba infertility
Klíčová slova anglicky
sperm cryopreservation testicular cancer infertility treatment
Štítky
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 3. 2. 2015 11:43, Ing. Mgr. Věra Pospíšilíková
Anotace
V originále
Aims. In this study we report our results with storage of cryopreserved semen intended for preservation and subsequent infertility treatment in men with testicular cancer during the last 18 years. Methods. Cryopreserved semen of 523 men with testicular cancer was collected between October 1995 and the end of December 2012. Semen of 34 men (6.5%) was used for fertilization of their partners. They underwent 57 treatment cycles with cryopreserved, fresh, and/or donor sperm. Results. A total of 557 men have decided to freeze their semen before cancer treatment. Azoospermia was diagnosed in 34 men (6.1%), and semen was cryopreserved in 532 patients. Seminoma was diagnosed in 283 men (54.1%) and nonseminomatous germ cell tumors in 240 men (45.9%). 34 patients who returned for infertility treatment underwent 46 treatment cycles with cryopreserved sperm. Totally 16 pregnancies were achieved, that is, 34.8% pregnancy rate. Conclusion. The testicular cancer survivors have a good chance of fathering a child by using sperm cryopreserved prior to the oncology treatment, even when it contains only limited number of spermatozoa.