CD36- and GPR120-mediated Ca2+ Signaling in Human Taste Bud
Cells Mediates Differential Responses to Fatty Acids and is
Altered in Obese Mice

J 2014

CD36- and GPR120-mediated Ca2+ Signaling in Human Taste Bud Cells Mediates Differential Responses to Fatty Acids and is Altered in Obese Mice

OZDENER, Mehmet Hakan; Selvakumar SUBRAMANIAM; Sinju SUNDARESAN; Omar ŠERÝ; Toshihiro HASHIMOTO et al.

Základní údaje

Originální název

CD36- and GPR120-mediated Ca2+ Signaling in Human Taste Bud Cells Mediates Differential Responses to Fatty Acids and is Altered in Obese Mice

Autoři

OZDENER, Mehmet Hakan; Selvakumar SUBRAMANIAM; Sinju SUNDARESAN; Omar ŠERÝ; Toshihiro HASHIMOTO; Yoshinori ASAKAWA; Philippe BESNARD; Nada A. ABUMRAD a Naim Akhtar KHAN

Vydání

Gastroenterology, American Gastroenterological Association, 2014, 0016-5085

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30105 Physiology

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 16.716

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/14:00074877

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova anglicky

Taste; human; Serotonin; Linoleic acid; GLP-1; Lipids

Štítky

AKR

Změněno: 2. 3. 2016 19:56, prof. RNDr. Omar Šerý, Ph.D.

Anotace

V originále

It is important to increase our understanding of gustatory detection of dietary fat and its contribution to fat preference. We studied the roles of the fat taste receptors CD36 and GPR120 and their interactions via Ca2+ signaling in fungiform taste bud cells (TBC). CD36 and GPR120 have non-overlapping roles in TBC signaling during oro-gustatory perception of dietary lipids; these are differentially regulated by obesity.

Návaznosti

NT11152, projekt VaV

Název: Epidemiologie a genetika Alzheimerovy choroby

Citovat

OZDENER, Mehmet Hakan; Selvakumar SUBRAMANIAM; Sinju SUNDARESAN; Omar ŠERÝ; Toshihiro HASHIMOTO; Yoshinori ASAKAWA; Philippe BESNARD; Nada A. ABUMRAD a Naim Akhtar KHAN. CD36- and GPR120-mediated Ca2+ Signaling in Human Taste Bud Cells Mediates Differential Responses to Fatty Acids and is Altered in Obese Mice. Gastroenterology. American Gastroenterological Association, 2014, roč. 146, č. 4, s. 995-1005. ISSN 0016-5085. Dostupné z: https://doi.org/10.1053/j.gastro.2014.01.006.

@article{1139033,
   author = {Ozdener, Mehmet Hakan and Subramaniam, Selvakumar and Sundaresan, Sinju and Šerý, Omar and Hashimoto, Toshihiro and Asakawa, Yoshinori and Besnard, Philippe and Abumrad, Nada A. and Khan, Naim Akhtar},
   article_number = {4},
   doi = {https://doi.org/10.1053/j.gastro.2014.01.006},
   keywords = {Taste; human; Serotonin; Linoleic acid; GLP-1; Lipids},
   language = {eng},
   issn = {0016-5085},
   journal = {Gastroenterology},
   title = {CD36- and GPR120-mediated Ca2+ Signaling in Human Taste Bud Cells Mediates Differential Responses to Fatty Acids and is Altered in Obese Mice},
   volume = {146},
   year = {2014}
}

TY  - JOUR
ID  - 1139033
AU  - Ozdener, Mehmet Hakan - Subramaniam, Selvakumar - Sundaresan, Sinju - Šerý, Omar - Hashimoto, Toshihiro - Asakawa, Yoshinori - Besnard, Philippe - Abumrad, Nada A. - Khan, Naim Akhtar
PY  - 2014
TI  - CD36- and GPR120-mediated Ca2+ Signaling in Human Taste Bud Cells Mediates Differential Responses to Fatty Acids and is Altered in Obese Mice
JF  - Gastroenterology
VL  - 146
IS  - 4
SP  - 995-1005
EP  - 995-1005
PB  - American Gastroenterological Association
SN  - 00165085
KW  - Taste
KW  - human
KW  - Serotonin
KW  - Linoleic acid
KW  - GLP-1
KW  - Lipids
N2  - It is important to increase our understanding of gustatory detection of dietary fat and its contribution to fat preference. We studied the roles of the fat taste receptors CD36 and GPR120 and their interactions via Ca2+ signaling in fungiform taste bud cells (TBC). CD36 and GPR120 have non-overlapping roles in TBC signaling during oro-gustatory perception of dietary lipids; these are differentially regulated by obesity.
ER  -

OZDENER, Mehmet Hakan; Selvakumar SUBRAMANIAM; Sinju SUNDARESAN; Omar ŠERÝ; Toshihiro HASHIMOTO; Yoshinori ASAKAWA; Philippe BESNARD; Nada A. ABUMRAD a Naim Akhtar KHAN. CD36- and GPR120-mediated Ca2+ Signaling in Human Taste Bud Cells Mediates Differential Responses to Fatty Acids and is Altered in Obese Mice. \textit{Gastroenterology}. American Gastroenterological Association, 2014, roč.~146, č.~4, s.~995-1005. ISSN~0016-5085. Dostupné z: https://doi.org/10.1053/j.gastro.2014.01.006.

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