A new liquid chromatography-tandem mass spectrometry method
using atmospheric pressure photo ionization for the
simultaneous determination of azaarenes and azaarones in Dutch
river sediments

J 2013

A new liquid chromatography-tandem mass spectrometry method using atmospheric pressure photo ionization for the simultaneous determination of azaarenes and azaarones in Dutch river sediments

BRULÍK, Jan; Zdeněk ŠIMEK a Pim DE VOOGT

Základní údaje

Originální název

A new liquid chromatography-tandem mass spectrometry method using atmospheric pressure photo ionization for the simultaneous determination of azaarenes and azaarones in Dutch river sediments

Autoři

BRULÍK, Jan; Zdeněk ŠIMEK a Pim DE VOOGT

Vydání

Journal of Chromatography A, AMSTERDAM, ELSEVIER SCIENCE BV, 2013, 0021-9673

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10511 Environmental sciences

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 4.258

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/13:00071055

Organizační jednotka

Přírodovědecká fakulta

DOI

https://doi.org/10.1016/j.chroma.2013.03.079

UT WoS

000319848000005

Klíčová slova anglicky

Azaarenes; Azaarones; PAH; APPI; LC-MS/MS; Sedimets

Štítky

AKR, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 27. 3. 2014 16:42, Ing. Andrea Mikešková

Anotace

V originále

A new method for the analysis of azaarenes and their degradation products (azaarones) was developed, optimized and validated using liquid chromatography coupled with atmospheric pressure photo ionization tandem mass spectrometric detection (LC-APPI/MS/MS). Seventeen compounds including 4 PAHs (naphthalene, anthracene, phenanthrene, benz[a]anthracene), 7 azaarenes (quinoline, acridine, phenanthridine, 5,6-benzoquinoline and 7,8-benzoquinoline, benzo[a]acridine, benzo[c]acridine), and 6 azaarones (2-OH-quinoline, 4-OH-quinoline, 5-OH-quinoline, 6-OH-quinoline, 9(10H)-acridone, 6(5H)phenanthridinone) were analyzed in sediment samples from Dutch rivers. All compounds were analyzed simultaneously in multi reaction monitoring (MRM) mode. Soxhlet extraction was used for the extraction of analytes from sediments. The limits of quantification of azaarenes and azaarones varied from 0.21 to 1.12 mu g/l and from 0.23 to 1.58 mu g/l, respectively. The limits of quantification for PAHs varied from 32 to 769 mu g/l. Matrix-independent recoveries of sediment samples were in the range 85-110%; matrix-dependent recoveries were in the range 73-148%, respectively. The method was tested on real sediment samples and the results were compared with a previous study in which GC/MS/MS was used for the simultaneous measurement of azaarenes and azaarones. 4-, 5- and 6-OH-quinolines and naphthalene, anthracene and phenanthrene were not present or below detection limits in some samples. All other analytes were present in samples in the concentration range 0.2-1200 ng/g (dw). To our knowledge, this is the first report showing the possibility of measurement non-polar polyaromatic hydrocarbons together with polar azaarenes and their degradation products azaarones simultaneously with sufficient sensitivity and accuracy using LC/MS/MS.

Návaznosti

ED0001/01/01, projekt VaV

Název: CETOCOEN

LM2011028, projekt VaV

Název: RECETOX ? Národní infrastruktura pro výzkum toxických látek v prostředí

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, RECETOX Národní infrastruktura pro výzkum toxických látek v prostředí

MSM0021622412, záměr

Název: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Akronym: INCHEMBIOL)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální , regionální a lokální úrovni

Citovat

BRULÍK, Jan; Zdeněk ŠIMEK a Pim DE VOOGT. A new liquid chromatography-tandem mass spectrometry method using atmospheric pressure photo ionization for the simultaneous determination of azaarenes and azaarones in Dutch river sediments. Journal of Chromatography A. AMSTERDAM: ELSEVIER SCIENCE BV, 2013, roč. 1294, č. 2013, s. 33-40. ISSN 0021-9673. Dostupné z: https://doi.org/10.1016/j.chroma.2013.03.079.

@article{1159401,
   author = {Brulík, Jan and Šimek, Zdeněk and de Voogt, Pim},
   article_location = {AMSTERDAM},
   article_number = {2013},
   doi = {https://doi.org/10.1016/j.chroma.2013.03.079},
   keywords = {Azaarenes; Azaarones; PAH; APPI; LC-MS/MS; Sedimets},
   language = {eng},
   issn = {0021-9673},
   journal = {Journal of Chromatography A},
   title = {A new liquid chromatography-tandem mass spectrometry method using atmospheric pressure photo ionization for the simultaneous determination of azaarenes and azaarones in Dutch river sediments},
   volume = {1294},
   year = {2013}
}

TY  - JOUR
ID  - 1159401
AU  - Brulík, Jan - Šimek, Zdeněk - de Voogt, Pim
PY  - 2013
TI  - A new liquid chromatography-tandem mass spectrometry method using atmospheric pressure photo ionization for the simultaneous determination of azaarenes and azaarones in Dutch river sediments
JF  - Journal of Chromatography A
VL  - 1294
IS  - 2013
SP  - 33-40
EP  - 33-40
PB  - ELSEVIER SCIENCE BV
SN  - 00219673
KW  - Azaarenes
KW  - Azaarones
KW  - PAH
KW  - APPI
KW  - LC-MS/MS
KW  - Sedimets
N2  - A new method for the analysis of azaarenes and their degradation products (azaarones) was developed, optimized and validated using liquid chromatography coupled with atmospheric pressure photo ionization tandem mass spectrometric detection (LC-APPI/MS/MS). Seventeen compounds including 4 PAHs (naphthalene, anthracene, phenanthrene, benz[a]anthracene), 7 azaarenes (quinoline, acridine, phenanthridine, 5,6-benzoquinoline and 7,8-benzoquinoline, benzo[a]acridine, benzo[c]acridine), and 6 azaarones (2-OH-quinoline, 4-OH-quinoline, 5-OH-quinoline, 6-OH-quinoline, 9(10H)-acridone, 6(5H)phenanthridinone) were analyzed in sediment samples from Dutch rivers. All compounds were analyzed simultaneously in multi reaction monitoring (MRM) mode. Soxhlet extraction was used for the extraction of analytes from sediments. The limits of quantification of azaarenes and azaarones varied from 0.21 to 1.12 mu g/l and from 0.23 to 1.58 mu g/l, respectively. The limits of quantification for PAHs varied from 32 to 769 mu g/l. Matrix-independent recoveries of sediment samples were in the range 85-110%; matrix-dependent recoveries were in the range 73-148%, respectively. The method was tested on real sediment samples and the results were compared with a previous study in which GC/MS/MS was used for the simultaneous measurement of azaarenes and azaarones. 4-, 5- and 6-OH-quinolines and naphthalene, anthracene and phenanthrene were not present or below detection limits in some samples. All other analytes were present in samples in the concentration range 0.2-1200 ng/g (dw). To our knowledge, this is the first report showing the possibility of measurement non-polar polyaromatic hydrocarbons together with polar azaarenes and their degradation products azaarones simultaneously with sufficient sensitivity and accuracy using LC/MS/MS.
ER  -

BRULÍK, Jan; Zdeněk ŠIMEK a Pim DE VOOGT. A new liquid chromatography-tandem mass spectrometry method using atmospheric pressure photo ionization for the simultaneous determination of azaarenes and azaarones in Dutch river sediments. \textit{Journal of Chromatography A}. AMSTERDAM: ELSEVIER SCIENCE BV, 2013, roč.~1294, č.~2013, s.~33-40. ISSN~0021-9673. Dostupné z: https://doi.org/10.1016/j.chroma.2013.03.079.

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