Estrogen-, androgen- and aryl hydrocarbon receptor mediated
activities in passive and composite samples from municipal
waste and surface waters

J 2013

Estrogen-, androgen- and aryl hydrocarbon receptor mediated activities in passive and composite samples from municipal waste and surface waters

JÁLOVÁ, Veronika, Barbora JAROŠOVÁ, Luděk BLÁHA, J.P. GIESY, T. OCELKA et. al.

Základní údaje

Originální název

Estrogen-, androgen- and aryl hydrocarbon receptor mediated activities in passive and composite samples from municipal waste and surface waters

Autoři

JÁLOVÁ, Veronika (203 Česká republika, domácí), Barbora JAROŠOVÁ (203 Česká republika, domácí), Luděk BLÁHA (203 Česká republika, domácí), J.P. GIESY (124 Kanada), T. OCELKA (203 Česká republika), R. GRABIC (203 Česká republika), J. JURCIKOVA (203 Česká republika), Branislav VRANA (703 Slovensko, domácí) a Klára HILSCHEROVÁ (203 Česká republika, garant, domácí)

Vydání

Environment International, OXFORD, PERGAMON-ELSEVIER SCIENCE LTD, 2013, 0160-4120

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10511 Environmental sciences

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 5.664

Kód RIV

RIV/00216224:14310/13:00071073

Organizační jednotka

Přírodovědecká fakulta

DOI

http://dx.doi.org/10.1016/j.envint.2013.06.024

UT WoS

000324901000039

Klíčová slova anglicky

Estrogenic; Androgenic; Cytotoxicity; Bioassay in vitro; Passive sampling; Dioxin-like

Štítky

AKR, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 4. 4. 2014 20:33, prof. RNDr. Luděk Bláha, Ph.D.

Anotace

V originále

Passive and composite sampling in combination with in vitro bioassays and identification and quantification of individual chemicals were applied to characterize pollution by compounds with several specific modes of action in urban area in the basin of two rivers, with 400,000 inhabitants and a variety of industrial activities. Two types of passive samplers, semipermeable membrane devices (SPMD) for hydrophobic contaminants and polar organic chemical integrative samplers (POCIS) for polar compounds such as pesticides and pharmaceuticals, were used to sample wastewater treatment plant (WWTP) influent and effluent as well as rivers upstream and downstream of the urban complex and the WWTP. Compounds with endocrine disruptive potency were detected in river water and WWTP influent and effluent. Year-round, monthly assessment of waste waters by bioassays documented estrogenic, androgenic and dioxin-like potency as well as cytotoxicity in influent waters of the WWTP and allowed characterization of seasonal variability of these biological potentials in waste waters. The WWTP effectively removed cytotoxic compounds, xenoestrogens and xenoandrogens. There was significant variability in treatment efficiency of dioxin-like potency. The study indicates that the WWTP, despite its up-to-date technology, can contribute endocrine disrupting compounds to the river. Riverine samples exhibited dioxin-like, antiestrogenic and antiandrogenic potencies. The study design enabled characterization of effects of the urban complex and the WWTP on the river. Concentrations of PAHs and contaminants and specific biological potencies sampled by POCIS decreased as a function of distance from the city.

Návaznosti

ED0001/01/01, projekt VaV

Název: CETOCOEN

EE2.3.20.0053, projekt VaV

Název: Podpora odborníků a mezinárodního networkingu v oblastech environmentálního výzkumu v ČR

2B08036, projekt VaV

Název: Nové molekulárně biologické a biochemické metody pro monitoring estrogenů a dalších chemických endokrinních disruptorů (Akronym: ENVISCREEN)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Nové molekulárně biologické a biochemické metody pro monitoring estrogenů a dalších chemických endokrinních disruptorů

Citovat

JÁLOVÁ, Veronika, Barbora JAROŠOVÁ, Luděk BLÁHA, J.P. GIESY, T. OCELKA, R. GRABIC, J. JURCIKOVA, Branislav VRANA a Klára HILSCHEROVÁ. Estrogen-, androgen- and aryl hydrocarbon receptor mediated activities in passive and composite samples from municipal waste and surface waters. Environment International. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD, 2013, roč. 59, č. 2013, s. 372-383. ISSN 0160-4120. Dostupné z: https://dx.doi.org/10.1016/j.envint.2013.06.024.

@article{1159451,
   author = {Jálová, Veronika and Jarošová, Barbora and Bláha, Luděk and Giesy, J.P. and Ocelka, T. and Grabic, R. and Jurcikova, J. and Vrana, Branislav and Hilscherová, Klára},
   article_location = {OXFORD},
   article_number = {2013},
   doi = {http://dx.doi.org/10.1016/j.envint.2013.06.024},
   keywords = {Estrogenic; Androgenic; Cytotoxicity; Bioassay in vitro; Passive sampling; Dioxin-like},
   language = {eng},
   issn = {0160-4120},
   journal = {Environment International},
   title = {Estrogen-, androgen- and aryl hydrocarbon receptor mediated activities in passive and composite samples from municipal waste and surface waters},
   volume = {59},
   year = {2013}
}

TY  - JOUR
ID  - 1159451
AU  - Jálová, Veronika - Jarošová, Barbora - Bláha, Luděk - Giesy, J.P. - Ocelka, T. - Grabic, R. - Jurcikova, J. - Vrana, Branislav - Hilscherová, Klára
PY  - 2013
TI  - Estrogen-, androgen- and aryl hydrocarbon receptor mediated activities in passive and composite samples from municipal waste and surface waters
JF  - Environment International
VL  - 59
IS  - 2013
SP  - 372-383
EP  - 372-383
PB  - PERGAMON-ELSEVIER SCIENCE LTD
SN  - 01604120
KW  - Estrogenic
KW  - Androgenic
KW  - Cytotoxicity
KW  - Bioassay in vitro
KW  - Passive sampling
KW  - Dioxin-like
N2  - Passive and composite sampling in combination with in vitro bioassays and identification and quantification of individual chemicals were applied to characterize pollution by compounds with several specific modes of action in urban area in the basin of two rivers, with 400,000 inhabitants and a variety of industrial activities. Two types of passive samplers, semipermeable membrane devices (SPMD) for hydrophobic contaminants and polar organic chemical integrative samplers (POCIS) for polar compounds such as pesticides and pharmaceuticals, were used to sample wastewater treatment plant (WWTP) influent and effluent as well as rivers upstream and downstream of the urban complex and the WWTP. Compounds with endocrine disruptive potency were detected in river water and WWTP influent and effluent. Year-round, monthly assessment of waste waters by bioassays documented estrogenic, androgenic and dioxin-like potency as well as cytotoxicity in influent waters of the WWTP and allowed characterization of seasonal variability of these biological potentials in waste waters. The WWTP effectively removed cytotoxic compounds, xenoestrogens and xenoandrogens. There was significant variability in treatment efficiency of dioxin-like potency. The study indicates that the WWTP, despite its up-to-date technology, can contribute endocrine disrupting compounds to the river. Riverine samples exhibited dioxin-like, antiestrogenic and antiandrogenic potencies. The study design enabled characterization of effects of the urban complex and the WWTP on the river. Concentrations of PAHs and contaminants and specific biological potencies sampled by POCIS decreased as a function of distance from the city.
ER  -

JÁLOVÁ, Veronika, Barbora JAROŠOVÁ, Luděk BLÁHA, J.P. GIESY, T. OCELKA, R. GRABIC, J. JURCIKOVA, Branislav VRANA a Klára HILSCHEROVÁ. Estrogen-, androgen- and aryl hydrocarbon receptor mediated activities in passive and composite samples from municipal waste and surface waters. \textit{Environment International}. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD, 2013, roč.~59, č.~2013, s.~372-383. ISSN~0160-4120. Dostupné z: https://dx.doi.org/10.1016/j.envint.2013.06.024.

Podrobný výpis o publikaci