| KNÍŽEK, Jiří, Pavel BOUCHAL, Bořivoj VOJTĚŠEK, Rudolf NENUTIL, Ladislav BERÁNEK, Martin KUBA a Pavel TOMŠÍK. Regression Algorithm for Identification of Biomarker Areas in SELDI-TOF Mass Spectra. International Journal of Imaging and Robotics. 2014, roč. 13, č. 2, s. 40-57. ISSN 2231-525X. |
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@article{1160440,
author = {Knížek, Jiří and Bouchal, Pavel and Vojtěšek, Bořivoj and Nenutil, Rudolf and Beránek, Ladislav and Kuba, Martin and Tomšík, Pavel},
article_number = {2},
keywords = {Markers; molecular biology; mass spectra; gnostics; supercomputer.},
language = {eng},
issn = {2231-525X},
journal = {International Journal of Imaging and Robotics},
title = {Regression Algorithm for Identification of Biomarker Areas in SELDI-TOF Mass Spectra},
url = {http://www.ceserp.com/cp-jour/index.php?journal=iji&page=article&op=view&path%5B%5D=2344},
volume = {13},
year = {2014}
}
TY - JOUR
ID - 1160440
AU - Knížek, Jiří - Bouchal, Pavel - Vojtěšek, Bořivoj - Nenutil, Rudolf - Beránek, Ladislav - Kuba, Martin - Tomšík, Pavel
PY - 2014
TI - Regression Algorithm for Identification of Biomarker Areas in SELDI-TOF Mass Spectra
JF - International Journal of Imaging and Robotics
VL - 13
IS - 2
SP - 40-57
EP - 40-57
SN - 2231525X
KW - Markers
KW - molecular biology
KW - mass spectra
KW - gnostics
KW - supercomputer.
UR - http://www.ceserp.com/cp-jour/index.php?journal=iji&page=article&op=view&path%5B%5D=2344
L2 - http://www.ceserp.com/cp-jour/index.php?journal=iji&page=article&op=view&path%5B%5D=2344
N2 - We describe a special regression algorithm for the identification of biomarker areas in SELDI-TOF mass spectra in this paper. Tests in a set of orthogonal polynomial regressions is the basic principle of this approach. Gnostic cluster analysis is then a very effective algorithmic complement, especially, for a case of excessive behavior of a part of (bio)markers. Apart from this another a new way of TIC-normalization of data is proposed in this paper. This new regression algorithm averages results significantly more effectively than software systems used. A very considerable amount of computation was made on a supercomputer.
ER -
KNÍŽEK, Jiří, Pavel BOUCHAL, Bořivoj VOJTĚŠEK, Rudolf NENUTIL, Ladislav BERÁNEK, Martin KUBA a Pavel TOMŠÍK. Regression Algorithm for Identification of Biomarker Areas in SELDI-TOF Mass Spectra. \textit{International Journal of Imaging and Robotics}. 2014, roč.~13, č.~2, s.~40-57. ISSN~2231-525X.
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