The epidemiology of thyroid cancer in the Czech Republic in comparison with other countries

LUKAS, Jindrich, Jiri DRABEK, David LUKAS, Ladislav DUŠEK a Jiří GATĚK. The epidemiology of thyroid cancer in the Czech Republic in comparison with other countries. Biomedical Papers, Olomouc: Palacky University, Olomouc: Palacky University, 2013, roč. 157, č. 3, s. 266-275. ISSN 1213-8118. doi:10.5507/bp.2012.086.
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Základní údaje
Originální název The epidemiology of thyroid cancer in the Czech Republic in comparison with other countries
Autoři LUKAS, Jindrich (203 Česká republika), Jiri DRABEK (203 Česká republika), David LUKAS (203 Česká republika), Ladislav DUŠEK (203 Česká republika, garant, domácí) a Jiří GATĚK (203 Česká republika).
Vydání Biomedical Papers, Olomouc: Palacky University, Olomouc, Palacky University, 2013, 1213-8118.
Další údaje
Originální jazyk angličtina
Typ výsledku Článek v odborném periodiku
Obor 3.2 Clinical medicine
Stát vydavatele Česká republika
Utajení není předmětem státního či obchodního tajemství
Impakt faktor Impact factor: 1.661
Kód RIV RIV/00216224:14110/13:00071888
Organizační jednotka Lékařská fakulta
Doi http://dx.doi.org/10.5507/bp.2012.086
UT WoS 000329091100011
Klíčová slova anglicky carcinoma of thyroid gland; epidemiology; risk factors
Příznaky Mezinárodní význam, Recenzováno
Změnil Změnila: Soňa Böhmová, učo 232884. Změněno: 7. 2. 2014 09:40.
Background. Thyroid cancer includes a broad spectrum of tumours with different prognoses. The global incidence has been increasing in recent years. Variables affecting its etiology are dietary, especially iodine intake and to a lesser extent selenium, environmental, like - ionizing radiation and, increased TSH level. These factors interplay with epigenetic and genetic changes within the cell. This review article presents thyroid cancer epidemiology, describes its main characteristics and the influence of environmental and lifestyle risk factors in the Czech Republic in comparison with other countries. Methods and Results. An epidemiological study of Czech patients with malignant thyroid carcinoma was made on the basis of the National Oncologic Registry (NOR) and Czech Statistical Office data summarized on the web portal SVOD. The data were compared with international data from the project GLOBOCAN 2008 Cancer Incidence and Mortality Worldwide. Apart from risk factors, prognostic factors with effect on patient survival were also analyzed. The survey showed that the incidence of thyroid cancer has been steadily growing in the Czech Republic. Since the beginning of the 1980s, it has increased 4 fold. It has a higher incidence than most other European countries but it is ranked with countries with an average and decreasing mortality. Obviously, the improved detection methods do not explain the growing incidence. The highest incidence is found for papillary carcinoma (PTC), now over 80% of cases. For follicular and medullar cancers, the incidence has not increased and for anaplastic carcinoma there is a slight decrease. Women over 40 years of age constitute the highest risk group. Conclusions. There are a number of reasons for these trends, such as improved diagnostic techniques using ultrasound and FNAB and more radical surgery. There are also dietary/environmental factors (iodine deficiency and to a lesser extent selenium), nitrates, polychlorinated biphenyls, increased ionizing radiation, and prolonged increase in TSH. The prognosis of patients with DTC depends on the age at the time of diagnosis. A favorable prognosis also depends on timely detection.
VytisknoutZobrazeno: 18. 4. 2019 21:08

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