Therapeutic strategies evaluated by the European Society of
Cutaneous Lupus Erythematosus (EUSCLE) Core Set Questionnaire
in more than 1000 patients with cutaneous lupus erythematosus

J 2013

Therapeutic strategies evaluated by the European Society of Cutaneous Lupus Erythematosus (EUSCLE) Core Set Questionnaire in more than 1000 patients with cutaneous lupus erythematosus

SIGGES, Johanna; Cyrus BIAZAR; Aysche LANDMANN; Vincent RULAND; Nikolaos PATSINAKIDIS et al.

Základní údaje

Originální název

Therapeutic strategies evaluated by the European Society of Cutaneous Lupus Erythematosus (EUSCLE) Core Set Questionnaire in more than 1000 patients with cutaneous lupus erythematosus

Autoři

Vydání

AUTOIMMUNITY REVIEWS, AMSTERDAM, ELSEVIER SCIENCE BV, 2013, 1568-9972

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30216 Dermatology and venereal diseases

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 7.095

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/13:00072489

Organizační jednotka

Lékařská fakulta

DOI

https://doi.org/10.1016/j.autrev.2012.10.005

UT WoS

000320684800002

Klíčová slova anglicky

TOPICAL CALCINEURIN INHIBITORS; LOW-DOSE METHOTREXATE; MYCOPHENOLATE-MOFETIL; REVISED CRITERIA; DOUBLE-BLIND; DAPSONE; PHOTOPROTECTION; CLASSIFICATION; THALIDOMIDE; MECHANISMS

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 28. 3. 2014 11:20, Ing. Mgr. Věra Pospíšilíková

Anotace

V originále

The aim of this prospective, cross-sectional, multicentre study performed by the European Society of Cutaneous Lupus Etythematosus (EUSCLE) was to investigate different therapeutic strategies and their efficacies in cutaneous lupus erythematosus (CLE) throughout Europe. Using the EUSCLE Core Set Questionnaire, topical and systemic treatment options were analysed in a total of 1002 patients (768 females and 234 males) with different CLE subtypes. The data were correlated with the Cutaneous Lupus Erythematosus Disease Area and Severity Index (CLASI) and the criteria of the American College of Rheumatology (ACR) for the classification of systemic lupus erythematosus. Sunscreens were applied by 84.0% of the study cohort and showed a high efficacy in preventing skin lesions in all disease subtypes, correlating with a lower CLASI activity score. Topical steroids were used in 81.5% of the patients, with an efficacy of 88.4%, whereas calcineurin inhibitors were applied in 16.4% of the study population and showed an efficacy of 61.7%. Systemic agents including antimalarials and several immunomodulating/-suppressive drugs, such as systemic steroids and methotrexate, were applied in 84.4% of the 1002 patients. The CLASI activity and damage score was higher in treated CLE patients compared to untreated patients, regardless of therapy with topical or systemic agents. In summary, preventive and therapeutic strategies of 1002 patients with different subtypes of CLE were analysed in this prospective, multicentre, Europe-wide study. Sunscreens were confirmed to be successful as preventive agents, and topical steroids showed a high efficacy, whereas antimalarials were used as first-line systemic treatment. (C) 2012 Elsevier B.V. All rights reserved.

Citovat

SIGGES, Johanna; Cyrus BIAZAR; Aysche LANDMANN; Vincent RULAND; Nikolaos PATSINAKIDIS; Susanne AMLER; Gisela BONSMANN; Annegret KUHN; M. HAUST; F. NYBERG; Z. BATA; L. MIHÁLYI; R. OLTEANU; R.M. PUJOL; J.M. SÁNCHEZ-SCHMIDT; L. MEDENICA; D. SKILJEVIC; A. REICH; J.C. SZEPIETOWSKI; C. Dalle VEDOVE; G. GIROLOMONI; T. HAWRO; A. ZALEWSKA-JANOWSKA; R. GLAESER; R. HUEGEL; Hana JEDLIČKOVÁ; A. BYGUM; R. LAURINAVICIENE; S. BENOIT; E. BROECKER; F.A. BAHMER; E. ABERER; N. WUTTE; J. LIPOZENCIC; B. MARINOVIC; M. SÁRDY; V. BEKOU; T. RUZICKA; C. FRANCES; B. SOUTOU; H. LEE; M. WORM; A. GRUSCHKE; N. HUNZELMANN; K. STEINBRINK; R. ROMITI; M. STICHERLING; C. ERFURT-BERGE; G. AVGERINOU; D. PAPAFRAGKAKI; E. ANTIGA; M. CAPRONI; B. MAYER; B. VOLC-PLATZER; A. KREUTER; C. TIGGES; P.M. HEIL a G. STINGL. Therapeutic strategies evaluated by the European Society of Cutaneous Lupus Erythematosus (EUSCLE) Core Set Questionnaire in more than 1000 patients with cutaneous lupus erythematosus. AUTOIMMUNITY REVIEWS. AMSTERDAM: ELSEVIER SCIENCE BV, 2013, roč. 12, č. 7, s. 694-702. ISSN 1568-9972. Dostupné z: https://doi.org/10.1016/j.autrev.2012.10.005.

@article{1168286,
   author = {Sigges, Johanna and Biazar, Cyrus and Landmann, Aysche and Ruland, Vincent and Patsinakidis, Nikolaos and Amler, Susanne and Bonsmann, Gisela and Kuhn, Annegret and Haust, M. and Nyberg, F. and Bata, Z. and Mihályi, L. and Olteanu, R. and Pujol, R.M. and SánchezandSchmidt, J.M. and Medenica, L. and Skiljevic, D. and Reich, A. and Szepietowski, J.C. and Vedove, C. Dalle and Girolomoni, G. and Hawro, T. and ZalewskaandJanowska, A. and Glaeser, R. and Huegel, R. and Jedličková, Hana and Bygum, A. and Laurinaviciene, R. and Benoit, S. and Broecker, E. and Bahmer, F.A. and Aberer, E. and Wutte, N. and Lipozencic, J. and Marinovic, B. and Sárdy, M. and Bekou, V. and Ruzicka, T. and Frances, C. and Soutou, B. and Lee, H. and Worm, M. and Gruschke, A. and Hunzelmann, N. and Steinbrink, K. and Romiti, R. and Sticherling, M. and ErfurtandBerge, C. and Avgerinou, G. and Papafragkaki, D. and Antiga, E. and Caproni, M. and Mayer, B. and VolcandPlatzer, B. and Kreuter, A. and Tigges, C. and Heil, P.M. and Stingl, G.},
   article_location = {AMSTERDAM},
   article_number = {7},
   doi = {https://doi.org/10.1016/j.autrev.2012.10.005},
   keywords = {TOPICAL CALCINEURIN INHIBITORS; LOW-DOSE METHOTREXATE; MYCOPHENOLATE-MOFETIL; REVISED CRITERIA; DOUBLE-BLIND; DAPSONE; PHOTOPROTECTION; CLASSIFICATION; THALIDOMIDE; MECHANISMS},
   language = {eng},
   issn = {1568-9972},
   journal = {AUTOIMMUNITY REVIEWS},
   note = {Autorka Jedličková dle WoS součástí "Group Author(s): EUSCLE".},
   title = {Therapeutic strategies evaluated by the European Society of Cutaneous Lupus Erythematosus (EUSCLE) Core Set Questionnaire in more than 1000 patients with cutaneous lupus erythematosus},
   volume = {12},
   year = {2013}
}

TY  - JOUR
ID  - 1168286
AU  - Sigges, Johanna - Biazar, Cyrus - Landmann, Aysche - Ruland, Vincent - Patsinakidis, Nikolaos - Amler, Susanne - Bonsmann, Gisela - Kuhn, Annegret - Haust, M. - Nyberg, F. - Bata, Z. - Mihályi, L. - Olteanu, R. - Pujol, R.M. - Sánchez-Schmidt, J.M. - Medenica, L. - Skiljevic, D. - Reich, A. - Szepietowski, J.C. - Vedove, C. Dalle - Girolomoni, G. - Hawro, T. - Zalewska-Janowska, A. - Glaeser, R. - Huegel, R. - Jedličková, Hana - Bygum, A. - Laurinaviciene, R. - Benoit, S. - Broecker, E. - Bahmer, F.A. - Aberer, E. - Wutte, N. - Lipozencic, J. - Marinovic, B. - Sárdy, M. - Bekou, V. - Ruzicka, T. - Frances, C. - Soutou, B. - Lee, H. - Worm, M. - Gruschke, A. - Hunzelmann, N. - Steinbrink, K. - Romiti, R. - Sticherling, M. - Erfurt-Berge, C. - Avgerinou, G. - Papafragkaki, D. - Antiga, E. - Caproni, M. - Mayer, B. - Volc-Platzer, B. - Kreuter, A. - Tigges, C. - Heil, P.M. - Stingl, G.
PY  - 2013
TI  - Therapeutic strategies evaluated by the European Society of Cutaneous Lupus Erythematosus (EUSCLE) Core Set Questionnaire in more than 1000 patients with cutaneous lupus erythematosus
JF  - AUTOIMMUNITY REVIEWS
VL  - 12
IS  - 7
SP  - 694-702
EP  - 694-702
PB  - ELSEVIER SCIENCE BV
SN  - 15689972
N1  - Autorka Jedličková dle WoS součástí "Group Author(s): EUSCLE".
KW  - TOPICAL CALCINEURIN INHIBITORS
KW  - LOW-DOSE METHOTREXATE
KW  - MYCOPHENOLATE-MOFETIL
KW  - REVISED CRITERIA
KW  - DOUBLE-BLIND
KW  - DAPSONE
KW  - PHOTOPROTECTION
KW  - CLASSIFICATION
KW  - THALIDOMIDE
KW  - MECHANISMS
N2  - The aim of this prospective, cross-sectional, multicentre study performed by the European Society of Cutaneous Lupus Etythematosus (EUSCLE) was to investigate different therapeutic strategies and their efficacies in cutaneous lupus erythematosus (CLE) throughout Europe. Using the EUSCLE Core Set Questionnaire, topical and systemic treatment options were analysed in a total of 1002 patients (768 females and 234 males) with different CLE subtypes. The data were correlated with the Cutaneous Lupus Erythematosus Disease Area and Severity Index (CLASI) and the criteria of the American College of Rheumatology (ACR) for the classification of systemic lupus erythematosus. Sunscreens were applied by 84.0% of the study cohort and showed a high efficacy in preventing skin lesions in all disease subtypes, correlating with a lower CLASI activity score. Topical steroids were used in 81.5% of the patients, with an efficacy of 88.4%, whereas calcineurin inhibitors were applied in 16.4% of the study population and showed an efficacy of 61.7%. Systemic agents including antimalarials and several immunomodulating/-suppressive drugs, such as systemic steroids and methotrexate, were applied in 84.4% of the 1002 patients. The CLASI activity and damage score was higher in treated CLE patients compared to untreated patients, regardless of therapy with topical or systemic agents. In summary, preventive and therapeutic strategies of 1002 patients with different subtypes of CLE were analysed in this prospective, multicentre, Europe-wide study. Sunscreens were confirmed to be successful as preventive agents, and topical steroids showed a high efficacy, whereas antimalarials were used as first-line systemic treatment. (C) 2012 Elsevier B.V. All rights reserved.
ER  -

SIGGES, Johanna; Cyrus BIAZAR; Aysche LANDMANN; Vincent RULAND; Nikolaos PATSINAKIDIS; Susanne AMLER; Gisela BONSMANN; Annegret KUHN; M. HAUST; F. NYBERG; Z. BATA; L. MIHÁLYI; R. OLTEANU; R.M. PUJOL; J.M. SÁNCHEZ-SCHMIDT; L. MEDENICA; D. SKILJEVIC; A. REICH; J.C. SZEPIETOWSKI; C. Dalle VEDOVE; G. GIROLOMONI; T. HAWRO; A. ZALEWSKA-JANOWSKA; R. GLAESER; R. HUEGEL; Hana JEDLIČKOVÁ; A. BYGUM; R. LAURINAVICIENE; S. BENOIT; E. BROECKER; F.A. BAHMER; E. ABERER; N. WUTTE; J. LIPOZENCIC; B. MARINOVIC; M. SÁRDY; V. BEKOU; T. RUZICKA; C. FRANCES; B. SOUTOU; H. LEE; M. WORM; A. GRUSCHKE; N. HUNZELMANN; K. STEINBRINK; R. ROMITI; M. STICHERLING; C. ERFURT-BERGE; G. AVGERINOU; D. PAPAFRAGKAKI; E. ANTIGA; M. CAPRONI; B. MAYER; B. VOLC-PLATZER; A. KREUTER; C. TIGGES; P.M. HEIL a G. STINGL. Therapeutic strategies evaluated by the European Society of Cutaneous Lupus Erythematosus (EUSCLE) Core Set Questionnaire in more than 1000 patients with cutaneous lupus erythematosus. \textit{AUTOIMMUNITY REVIEWS}. AMSTERDAM: ELSEVIER SCIENCE BV, 2013, roč.~12, č.~7, s.~694-702. ISSN~1568-9972. Dostupné z: https://doi.org/10.1016/j.autrev.2012.10.005.

Přehled o publikaci