Cutaneous lupus erythematosus: First multicenter database
analysis of 1002 patients from the European Society of
Cutaneous Lupus Erythematosus (EUSCLE)

J 2013

Cutaneous lupus erythematosus: First multicenter database analysis of 1002 patients from the European Society of Cutaneous Lupus Erythematosus (EUSCLE)

BIAZAR, Cyrus; Johanna SIGGES; Nikolaos PATSINAKIDIS; Vincent RULAND; Susanne AMLER et al.

Základní údaje

Originální název

Cutaneous lupus erythematosus: First multicenter database analysis of 1002 patients from the European Society of Cutaneous Lupus Erythematosus (EUSCLE)

Autoři

BIAZAR, Cyrus; Johanna SIGGES; Nikolaos PATSINAKIDIS; Vincent RULAND; Susanne AMLER; Gisela BONSMANN; Annegret KUHN; M. HAUST; F. NYBERG; Z. BATA; L. MIHÁLYI; R. OLTEANU; R.M. PUJOL; J.M. SÁNCHEZ-SCHMIDT; L. MEDENICA; D. SKILJEVIC; A. REICH; J.C. SZEPIETOWSKI; C. Dalle VEDOVE; G. GIROLOMONI; T. HAWRO; A. ZALEWSKA-JANOWSKA; R. GLAESER; R. HUEGEL; Hana JEDLIČKOVÁ; A. BYGUM; R. LAURINAVICIENE; S. BENOIT; E. BROECKER; F.A. BAHMER; E. ABERER; N. WUTTE; J. LIPOZENCIC; B. MARINOVIC; M. SÁRDY; V. BEKOU; T. RUZICKA; C. FRANCES; B. SOUTOU; H. LEE; M. WORM; A. GRUSCHKE; N. HUNZELMANN; K. STEINBRINK; R. ROMITI; M. STICHERLING; C. ERFURT-BERGE; G. AVGERINOU; D. PAPAFRAGKAKI; E. ANTIGA; M. CAPRONI; B. MAYER; B. VOLC-PLATZER; A. KREUTER; C. TIGGES; P.M. HEIL a G. STINGL

Vydání

AUTOIMMUNITY REVIEWS, AMSTERDAM, ELSEVIER SCIENCE BV, 2013, 1568-9972

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30216 Dermatology and venereal diseases

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 7.095

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/13:00072492

Organizační jednotka

Lékařská fakulta

DOI

https://doi.org/10.1016/j.autrev.2012.08.019

UT WoS

000314435200015

Klíčová slova anglicky

Autoimmune disease; Cutaneous lupus erythematosus; Europe; Database analysis; Questionnaire

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 28. 3. 2014 11:16, Ing. Mgr. Věra Pospíšilíková

Anotace

V originále

In this prospective, cross-sectional, multicenter study, we assessed clinical and laboratory characteristics from patients with cutaneous lupus erythematosus (CLE) using the Core Set Questionnaire of the European Society of Cutaneous Lupus Erythematosus (EUSCLE). 1002 (768 females, 234 males) patients with different subtypes of CLE, such as acute CLE (ACLE, 304 patients), subacute CLE (SCLE, 236 patients), chronic CLE (CCLE, 397 patients), and intermittent CLE (ICLE, 65 patients), from 13 European countries were collected and statistically analyzed by an SPSS database. The main outcome measures included gender, age at onset of disease, LE-specific and LE-nonspecific skin lesions, photosensitivity, laboratory features, and the criteria of the American College of Rheumatology (ACR) for the classification of systemic lupus erythematosus. The mean age at onset of disease was 43.0 +/- 15.7 years and differed significantly between the CLE subtypes. In 347 (34.6%) of the 1002 patients, two or more CLE subtypes were diagnosed during the course of the disease and 453 (45.2%) presented with LE-nonspecific manifestations. Drug-induced CLE and Sjogren's Syndrome had the highest prevalence in SCLE patients (13.1% and 14.0%, respectively). Photosensitivity was significantly more frequent in patients with ACLE, SCLE, and ICLE compared with those with CCLE. The detection of antinuclear antibodies such as anti-Ro/SSA and anti-La/SSB antibodies revealed further significant differences between the CLE subtypes. In summary, the EUSCLE Core Set Questionnaire and its database facilitate the analysis of clinical and laboratory features in a high number of patients with CLE and will contribute to standardized assessment and monitoring of the disease in Europe. (c) 2012 Elsevier B.V. All rights reserved.

Citovat

@article{1168290,
   author = {Biazar, Cyrus and Sigges, Johanna and Patsinakidis, Nikolaos and Ruland, Vincent and Amler, Susanne and Bonsmann, Gisela and Kuhn, Annegret and Haust, M. and Nyberg, F. and Bata, Z. and Mihályi, L. and Olteanu, R. and Pujol, R.M. and SánchezandSchmidt, J.M. and Medenica, L. and Skiljevic, D. and Reich, A. and Szepietowski, J.C. and Vedove, C. Dalle and Girolomoni, G. and Hawro, T. and ZalewskaandJanowska, A. and Glaeser, R. and Huegel, R. and Jedličková, Hana and Bygum, A. and Laurinaviciene, R. and Benoit, S. and Broecker, E. and Bahmer, F.A. and Aberer, E. and Wutte, N. and Lipozencic, J. and Marinovic, B. and Sárdy, M. and Bekou, V. and Ruzicka, T. and Frances, C. and Soutou, B. and Lee, H. and Worm, M. and Gruschke, A. and Hunzelmann, N. and Steinbrink, K. and Romiti, R. and Sticherling, M. and ErfurtandBerge, C. and Avgerinou, G. and Papafragkaki, D. and Antiga, E. and Caproni, M. and Mayer, B. and VolcandPlatzer, B. and Kreuter, A. and Tigges, C. and Heil, P.M. and Stingl, G.},
   article_location = {AMSTERDAM},
   article_number = {3},
   doi = {https://doi.org/10.1016/j.autrev.2012.08.019},
   keywords = {Autoimmune disease; Cutaneous lupus erythematosus; Europe; Database analysis; Questionnaire},
   language = {eng},
   issn = {1568-9972},
   journal = {AUTOIMMUNITY REVIEWS},
   note = {Autorka Jedličková dle WoS součástí "Group Author(s): EUSCLE".},
   title = {Cutaneous lupus erythematosus: First multicenter database analysis of 1002 patients from the European Society of Cutaneous Lupus Erythematosus (EUSCLE)},
   volume = {12},
   year = {2013}
}

TY  - JOUR
ID  - 1168290
AU  - Biazar, Cyrus - Sigges, Johanna - Patsinakidis, Nikolaos - Ruland, Vincent - Amler, Susanne - Bonsmann, Gisela - Kuhn, Annegret - Haust, M. - Nyberg, F. - Bata, Z. - Mihályi, L. - Olteanu, R. - Pujol, R.M. - Sánchez-Schmidt, J.M. - Medenica, L. - Skiljevic, D. - Reich, A. - Szepietowski, J.C. - Vedove, C. Dalle - Girolomoni, G. - Hawro, T. - Zalewska-Janowska, A. - Glaeser, R. - Huegel, R. - Jedličková, Hana - Bygum, A. - Laurinaviciene, R. - Benoit, S. - Broecker, E. - Bahmer, F.A. - Aberer, E. - Wutte, N. - Lipozencic, J. - Marinovic, B. - Sárdy, M. - Bekou, V. - Ruzicka, T. - Frances, C. - Soutou, B. - Lee, H. - Worm, M. - Gruschke, A. - Hunzelmann, N. - Steinbrink, K. - Romiti, R. - Sticherling, M. - Erfurt-Berge, C. - Avgerinou, G. - Papafragkaki, D. - Antiga, E. - Caproni, M. - Mayer, B. - Volc-Platzer, B. - Kreuter, A. - Tigges, C. - Heil, P.M. - Stingl, G.
PY  - 2013
TI  - Cutaneous lupus erythematosus: First multicenter database analysis of 1002 patients from the European Society of Cutaneous Lupus Erythematosus (EUSCLE)
JF  - AUTOIMMUNITY REVIEWS
VL  - 12
IS  - 3
SP  - 444-454
EP  - 444-454
PB  - ELSEVIER SCIENCE BV
SN  - 15689972
N1  - Autorka Jedličková dle WoS součástí "Group Author(s): EUSCLE".
KW  - Autoimmune disease
KW  - Cutaneous lupus erythematosus
KW  - Europe
KW  - Database analysis
KW  - Questionnaire
N2  - In this prospective, cross-sectional, multicenter study, we assessed clinical and laboratory characteristics from patients with cutaneous lupus erythematosus (CLE) using the Core Set Questionnaire of the European Society of Cutaneous Lupus Erythematosus (EUSCLE). 1002 (768 females, 234 males) patients with different subtypes of CLE, such as acute CLE (ACLE, 304 patients), subacute CLE (SCLE, 236 patients), chronic CLE (CCLE, 397 patients), and intermittent CLE (ICLE, 65 patients), from 13 European countries were collected and statistically analyzed by an SPSS database. The main outcome measures included gender, age at onset of disease, LE-specific and LE-nonspecific skin lesions, photosensitivity, laboratory features, and the criteria of the American College of Rheumatology (ACR) for the classification of systemic lupus erythematosus. The mean age at onset of disease was 43.0 +/- 15.7 years and differed significantly between the CLE subtypes. In 347 (34.6%) of the 1002 patients, two or more CLE subtypes were diagnosed during the course of the disease and 453 (45.2%) presented with LE-nonspecific manifestations. Drug-induced CLE and Sjogren's Syndrome had the highest prevalence in SCLE patients (13.1% and 14.0%, respectively). Photosensitivity was significantly more frequent in patients with ACLE, SCLE, and ICLE compared with those with CCLE. The detection of antinuclear antibodies such as anti-Ro/SSA and anti-La/SSB antibodies revealed further significant differences between the CLE subtypes. In summary, the EUSCLE Core Set Questionnaire and its database facilitate the analysis of clinical and laboratory features in a high number of patients with CLE and will contribute to standardized assessment and monitoring of the disease in Europe. (c) 2012 Elsevier B.V. All rights reserved.
ER  -

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