Pancreatic stone protein – A possible biomarker of multiorgan
failure and mortality in children sepsis

J 2014

Pancreatic stone protein – A possible biomarker of multiorgan failure and mortality in children sepsis

ŽUREK, Jiří, Michal KÝR, Martin VAVŘINA a Michal FEDORA

Základní údaje

Originální název

Pancreatic stone protein – A possible biomarker of multiorgan failure and mortality in children sepsis

Autoři

ŽUREK, Jiří (203 Česká republika, garant, domácí), Michal KÝR (203 Česká republika, domácí), Martin VAVŘINA (203 Česká republika, domácí) a Michal FEDORA (203 Česká republika, domácí)

Vydání

Cytokine, Academic Press, 2014, 1043-4666

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30209 Paediatrics

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 2.664

Kód RIV

RIV/00216224:14110/14:00075154

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1016/j.cyto.2014.01.009

UT WoS

000333729200003

Klíčová slova anglicky

Children; Mortality; Pancreatic stone protein; Regenerating protein 1 alpha; Sepsis

Štítky

EL OK

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 9. 7. 2014 12:17, Ing. Mgr. Věra Pospíšilíková

Anotace

V originále

Pancreatic stone protein is associated with infection. Pancreatic stone protein did not differ between SIRS and sepsis. Pancreatic stone protein levels were higher in patients who died. Pancreatic stone protein (PSP)/regenerating protein 1-alpha (reg) is associated with inflammation, infection, and other disease-related stimuli. The prognostic value of PSP/. reg among critically ill pediatric patients is unknown. The aim of this pilot study was to evaluate PSP/. reg in children with systemic inflammatory response syndrome or sepsis.Prospective observational study, a five day evaluation period in children 0-19. years old with systemic inflammatory response syndrome or septic state. Blood tests to determine levels of PSP/. reg were obtained as long as the patient met the criteria for systemic inflammatory response syndrome or sepsis.PSP/. reg levels did not differ between patients with systemic inflammatory response syndrome and septic condition until organ dysfunction signs were present. PSP/. reg levels were significantly higher in patients with a PELOD score of 12 or higher or in those with MODS. Patients who died tended to have higher PSP/. reg levels.

Citovat

ŽUREK, Jiří, Michal KÝR, Martin VAVŘINA a Michal FEDORA. Pancreatic stone protein – A possible biomarker of multiorgan failure and mortality in children sepsis. Cytokine. Academic Press, 2014, roč. 66, č. 2, s. 106-111. ISSN 1043-4666. Dostupné z: https://dx.doi.org/10.1016/j.cyto.2014.01.009.

@article{1169423,
   author = {Žurek, Jiří and Kýr, Michal and Vavřina, Martin and Fedora, Michal},
   article_number = {2},
   doi = {http://dx.doi.org/10.1016/j.cyto.2014.01.009},
   keywords = {Children; Mortality; Pancreatic stone protein; Regenerating protein 1 alpha; Sepsis},
   language = {eng},
   issn = {1043-4666},
   journal = {Cytokine},
   title = {Pancreatic stone protein – A possible biomarker of multiorgan failure and mortality in children sepsis},
   volume = {66},
   year = {2014}
}

TY  - JOUR
ID  - 1169423
AU  - Žurek, Jiří - Kýr, Michal - Vavřina, Martin - Fedora, Michal
PY  - 2014
TI  - Pancreatic stone protein – A possible biomarker of multiorgan failure and mortality in children sepsis
JF  - Cytokine
VL  - 66
IS  - 2
SP  - 106-111
EP  - 106-111
PB  - Academic Press
SN  - 10434666
KW  - Children
KW  - Mortality
KW  - Pancreatic stone protein
KW  - Regenerating protein 1 alpha
KW  - Sepsis
N2  - Pancreatic stone protein is associated with infection. Pancreatic stone protein did not differ between SIRS and sepsis. Pancreatic stone protein levels were higher in patients who died. Pancreatic stone protein (PSP)/regenerating protein 1-alpha (reg) is associated with inflammation, infection, and other disease-related stimuli. The prognostic value of PSP/. reg among critically ill pediatric patients is unknown. The aim of this pilot study was to evaluate PSP/. reg in children with systemic inflammatory response syndrome or sepsis.Prospective observational study, a five day evaluation period in children 0-19. years old with systemic inflammatory response syndrome or septic state. Blood tests to determine levels of PSP/. reg were obtained as long as the patient met the criteria for systemic inflammatory response syndrome or sepsis.PSP/. reg levels did not differ between patients with systemic inflammatory response syndrome and septic condition until organ dysfunction signs were present. PSP/. reg levels were significantly higher in patients with a PELOD score of 12 or higher or in those with MODS. Patients who died tended to have higher PSP/. reg levels.
ER  -

ŽUREK, Jiří, Michal KÝR, Martin VAVŘINA a Michal FEDORA. Pancreatic stone protein – A possible biomarker of multiorgan failure and mortality in children sepsis. \textit{Cytokine}. Academic Press, 2014, roč.~66, č.~2, s.~106-111. ISSN~1043-4666. Dostupné z: https://dx.doi.org/10.1016/j.cyto.2014.01.009.

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