Hemimandibulectomy and therapeutic neck dissection with
radiotherapy in the treatment of oral squamous cell carcinoma
involving mandible: a critical review of treatment protocol in
the years 1994-2004

J 2010

Hemimandibulectomy and therapeutic neck dissection with radiotherapy in the treatment of oral squamous cell carcinoma involving mandible: a critical review of treatment protocol in the years 1994-2004

HOFFMANNOVÁ, Jiřina, René FOLTÁN, Marek VLK, Michal ŠIPOŠ, Edita HORKÁ et. al.

Základní údaje

Originální název

Hemimandibulectomy and therapeutic neck dissection with radiotherapy in the treatment of oral squamous cell carcinoma involving mandible: a critical review of treatment protocol in the years 1994-2004

Autoři

HOFFMANNOVÁ, Jiřina (203 Česká republika), René FOLTÁN (203 Česká republika), Marek VLK (203 Česká republika), Michal ŠIPOŠ (203 Česká republika), Edita HORKÁ (203 Česká republika), Gabriela PAVLÍKOVÁ (203 Česká republika), Roman KUFA (203 Česká republika), Oliver BULIK (203 Česká republika, garant, domácí) a Jiří ŠEDÝ (203 Česká republika)

Vydání

International Journal of Oral and Maxillofacial Surgery, EDINBURGH, Scotland, CHURCHILL LIVINGSTONE, 2010, 0901-5027

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30200 3.2 Clinical medicine

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 1.302

Kód RIV

RIV/00216224:14110/10:00075346

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1016/j.ijom.2010.03.010

UT WoS

000279570600007

Klíčová slova anglicky

squamous cell carcinoma; oral cavity; retrospective study; tumour; actinotherapy; hemimandibulectomy; neck dissection

Štítky

EL OK

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 14. 5. 2014 15:40, Ing. Mgr. Věra Pospíšilíková

Anotace

V originále

This retrospective non-randomized 10-year follow-up study compared 147 patients with squamous cell carcinoma (SCC) of the oral cavity requiring hemimandibulectomy, treated by surgical resection, therapeutic neck dissection and radiotherapy The 5-year survival rates were compared related to localization, size of the tumour, infiltration of locoregional lymph nodes, distant metastases, histopathological grading, radicality of surgery, and invasion of tumour into the mandible Occurrence of tumour relapse and its localization was studied The mean 5-year survival rate was 26% Patients with SCC of the mandibular alveolar process had higher rates, the lowest rates occurred in SCC of the buccal mucosa. Survival rate was significantly lower with insufficient resection of the tumour (85% relapse) An important number of patients with radical resection died within 3 months of surgery In almost 55% of the mandibles turnout was not present In 5% of infiltrated mandibles, dissemination into inferior alveolar nerve was proven Decreasing survival rate was seen with increasing size of tumour and higher histological grade Therapeutic neck dissection significantly reduces survival rate and increases the percentage of lymph node relapse. Elective neck dissection should be performed in SCC requiring hemimandibulectomy Primary reconstruction should reverse the high percentage of postoperative complication arising from increased radicality

Citovat

HOFFMANNOVÁ, Jiřina, René FOLTÁN, Marek VLK, Michal ŠIPOŠ, Edita HORKÁ, Gabriela PAVLÍKOVÁ, Roman KUFA, Oliver BULIK a Jiří ŠEDÝ. Hemimandibulectomy and therapeutic neck dissection with radiotherapy in the treatment of oral squamous cell carcinoma involving mandible: a critical review of treatment protocol in the years 1994-2004. International Journal of Oral and Maxillofacial Surgery. EDINBURGH, Scotland: CHURCHILL LIVINGSTONE, 2010, roč. 39, č. 6, s. 561-567. ISSN 0901-5027. Dostupné z: https://dx.doi.org/10.1016/j.ijom.2010.03.010.

@article{1180440,
   author = {Hoffmannová, Jiřina and Foltán, René and Vlk, Marek and Šipoš, Michal and Horká, Edita and Pavlíková, Gabriela and Kufa, Roman and Bulik, Oliver and Šedý, Jiří},
   article_location = {EDINBURGH, Scotland},
   article_number = {6},
   doi = {http://dx.doi.org/10.1016/j.ijom.2010.03.010},
   keywords = {squamous cell carcinoma; oral cavity; retrospective study; tumour; actinotherapy; hemimandibulectomy; neck dissection},
   language = {eng},
   issn = {0901-5027},
   journal = {International Journal of Oral and Maxillofacial Surgery},
   title = {Hemimandibulectomy and therapeutic neck dissection with radiotherapy in the treatment of oral squamous cell carcinoma involving mandible: a critical review of treatment protocol in the years 1994-2004},
   volume = {39},
   year = {2010}
}

TY  - JOUR
ID  - 1180440
AU  - Hoffmannová, Jiřina - Foltán, René - Vlk, Marek - Šipoš, Michal - Horká, Edita - Pavlíková, Gabriela - Kufa, Roman - Bulik, Oliver - Šedý, Jiří
PY  - 2010
TI  - Hemimandibulectomy and therapeutic neck dissection with radiotherapy in the treatment of oral squamous cell carcinoma involving mandible: a critical review of treatment protocol in the years 1994-2004
JF  - International Journal of Oral and Maxillofacial Surgery
VL  - 39
IS  - 6
SP  - 561-567
EP  - 561-567
PB  - CHURCHILL LIVINGSTONE
SN  - 09015027
KW  - squamous cell carcinoma
KW  - oral cavity
KW  - retrospective study
KW  - tumour
KW  - actinotherapy
KW  - hemimandibulectomy
KW  - neck dissection
N2  - This retrospective non-randomized 10-year follow-up study compared 147 patients with squamous cell carcinoma (SCC) of the oral cavity requiring hemimandibulectomy, treated by surgical resection, therapeutic neck dissection and radiotherapy The 5-year survival rates were compared related to localization, size of the tumour, infiltration of locoregional lymph nodes, distant metastases, histopathological grading, radicality of surgery, and invasion of tumour into the mandible Occurrence of tumour relapse and its localization was studied The mean 5-year survival rate was 26% Patients with SCC of the mandibular alveolar process had higher rates, the lowest rates occurred in SCC of the buccal mucosa. Survival rate was significantly lower with insufficient resection of the tumour (85% relapse) An important number of patients with radical resection died within 3 months of surgery In almost 55% of the mandibles turnout was not present In 5% of infiltrated mandibles, dissemination into inferior alveolar nerve was proven Decreasing survival rate was seen with increasing size of tumour and higher histological grade Therapeutic neck dissection significantly reduces survival rate and increases the percentage of lymph node relapse. Elective neck dissection should be performed in SCC requiring hemimandibulectomy Primary reconstruction should reverse the high percentage of postoperative complication arising from increased radicality
ER  -

HOFFMANNOVÁ, Jiřina, René FOLTÁN, Marek VLK, Michal ŠIPOŠ, Edita HORKÁ, Gabriela PAVLÍKOVÁ, Roman KUFA, Oliver BULIK a Jiří ŠEDÝ. Hemimandibulectomy and therapeutic neck dissection with radiotherapy in the treatment of oral squamous cell carcinoma involving mandible: a critical review of treatment protocol in the years 1994-2004. \textit{International Journal of Oral and Maxillofacial Surgery}. EDINBURGH, Scotland: CHURCHILL LIVINGSTONE, 2010, roč.~39, č.~6, s.~561-567. ISSN~0901-5027. Dostupné z: https://dx.doi.org/10.1016/j.ijom.2010.03.010.

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