| PASZEKOVÁ, Helena, Fedor KRYUKOV, Lenka KUBICZKOVÁ, Roman HÁJEK a Sabina ŠEVČÍKOVÁ. High-Risk Multiple Myeloma: Different Definitions, Different Outcomes? Clinical lymphoma, myeloma & leukemia. CIG MEDIA GROUP, LP, 2014, roč. 14, č. 1, s. 24-30. ISSN 2152-2650. Dostupné z: https://dx.doi.org/10.1016/j.clml.2013.09.004. |
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@article{1180894,
author = {Paszeková, Helena and Kryukov, Fedor and Kubiczková, Lenka and Hájek, Roman and Ševčíková, Sabina},
article_number = {1},
doi = {http://dx.doi.org/10.1016/j.clml.2013.09.004},
keywords = {Cytogenetics; GEP; High-risk disease; MGUS; Multiple myeloma; Prognosis},
language = {eng},
issn = {2152-2650},
journal = {Clinical lymphoma, myeloma & leukemia},
title = {High-Risk Multiple Myeloma: Different Definitions, Different Outcomes?},
volume = {14},
year = {2014}
}
TY - JOUR
ID - 1180894
AU - Paszeková, Helena - Kryukov, Fedor - Kubiczková, Lenka - Hájek, Roman - Ševčíková, Sabina
PY - 2014
TI - High-Risk Multiple Myeloma: Different Definitions, Different Outcomes?
JF - Clinical lymphoma, myeloma & leukemia
VL - 14
IS - 1
SP - 24-30
EP - 24-30
PB - CIG MEDIA GROUP, LP
SN - 21522650
KW - Cytogenetics
KW - GEP
KW - High-risk disease
KW - MGUS
KW - Multiple myeloma
KW - Prognosis
N2 - Multiple myeloma (MM) is a clonal plasma cell malignancy. Although MM is still not completely curable, it can be maintained at the level of a long-term chronic condition. Irrespective of the treatment strategy, relapse is still a major problem for most patients. Approximately 10% to 15% of all MM patients relapse early and have poor prognosis and outcome. Currently, there are many ways of identifying these high-risk patients using cytogenetics or molecular biology. Despite these various approaches to definition of high risk patients, a clear definition of high-risk MM has not been widely accepted. In this review, we discuss and compare various approaches, and their strengths and weaknesses in early identification of high-risk MM patients.
ER -
PASZEKOVÁ, Helena, Fedor KRYUKOV, Lenka KUBICZKOVÁ, Roman HÁJEK a Sabina ŠEVČÍKOVÁ. High-Risk Multiple Myeloma: Different Definitions, Different Outcomes? \textit{Clinical lymphoma, myeloma \&{} leukemia}. CIG MEDIA GROUP, LP, 2014, roč.~14, č.~1, s.~24-30. ISSN~2152-2650. Dostupné z: https://dx.doi.org/10.1016/j.clml.2013.09.004.
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