Combined effect of silver nanoparticles and therapeutical
ultrasound on ovarian carcinoma cells A2780

J 2014

Combined effect of silver nanoparticles and therapeutical ultrasound on ovarian carcinoma cells A2780

BERNARD, Vladan, Vojtěch MORNSTEIN, Josef JAROŠ, Miroslava SEDLÁČKOVÁ, Jiřina ŠKORPÍKOVÁ et. al.

Základní údaje

Originální název

Combined effect of silver nanoparticles and therapeutical ultrasound on ovarian carcinoma cells A2780

Autoři

BERNARD, Vladan (203 Česká republika, garant, domácí), Vojtěch MORNSTEIN (203 Česká republika, domácí), Josef JAROŠ (203 Česká republika, domácí), Miroslava SEDLÁČKOVÁ (203 Česká republika, domácí) a Jiřina ŠKORPÍKOVÁ (203 Česká republika, domácí)

Vydání

Journal of Applied Biomedicine, České Budějovice, Faculty of Health and Social Care, University of South Bohemia, 2014, 1214-021X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10610 Biophysics

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 1.302

Kód RIV

RIV/00216224:14110/14:00073699

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1016/j.jab.2014.01.002

UT WoS

000340867600002

Klíčová slova anglicky

Nanoparticle; nanosilver; sonodynamic therapy; Ultrasound

Štítky

EL OK

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 24. 4. 2015 13:08, Soňa Böhmová

Anotace

V originále

Antibacterial activity of silver nanoparticles is widely known and used. The effect of application of therapeutical ultrasonic field in the presence of silver nanoparticles <100 nm was examined on human ovarian carcinoma cell A2780. The cell's viability was examined by MTT assay and by life-time microscopy. The presence of nanoparticles in the cell was examined by using electron transmission microscopy. Experimental results indicate a significant decrease of viability of cell, which was affected by the combined action of ultrasound field and silver nanoparticles, compared to the separate exposure of silver nanoparticles or ultrasonic field. The experiments showed a significant effect of succession of application of these two factors. The presence of nanoparticles inside cells after incubation was showed. The results show the possibility of using of ultrasonic field as a factor that can significantly affect cell viability in the presence of silver nanoparticles.

Návaznosti

GP13-04408P, projekt VaV

Název: Ovlivnění nádorových buněk kombinovaným působením nanočástic a ultrazvukového pole

Investor: Grantová agentura ČR, Ovlivnění nádorových buněk kombinovaným působením nanočástic a ultrazvukového pole

Citovat

BERNARD, Vladan, Vojtěch MORNSTEIN, Josef JAROŠ, Miroslava SEDLÁČKOVÁ a Jiřina ŠKORPÍKOVÁ. Combined effect of silver nanoparticles and therapeutical ultrasound on ovarian carcinoma cells A2780. Journal of Applied Biomedicine. České Budějovice: Faculty of Health and Social Care, University of South Bohemia, 2014, roč. 12, č. 3, s. 137-145. ISSN 1214-021X. Dostupné z: https://dx.doi.org/10.1016/j.jab.2014.01.002.

@article{1186372,
   author = {Bernard, Vladan and Mornstein, Vojtěch and Jaroš, Josef and Sedláčková, Miroslava and Škorpíková, Jiřina},
   article_location = {České Budějovice},
   article_number = {3},
   doi = {http://dx.doi.org/10.1016/j.jab.2014.01.002},
   keywords = {Nanoparticle; nanosilver; sonodynamic therapy; Ultrasound},
   language = {eng},
   issn = {1214-021X},
   journal = {Journal of Applied Biomedicine},
   title = {Combined effect of silver nanoparticles and therapeutical ultrasound on ovarian carcinoma cells A2780},
   url = {http://www.sciencedirect.com/science/article/pii/S1214021X14000283},
   volume = {12},
   year = {2014}
}

TY  - JOUR
ID  - 1186372
AU  - Bernard, Vladan - Mornstein, Vojtěch - Jaroš, Josef - Sedláčková, Miroslava - Škorpíková, Jiřina
PY  - 2014
TI  - Combined effect of silver nanoparticles and therapeutical ultrasound on ovarian carcinoma cells A2780
JF  - Journal of Applied Biomedicine
VL  - 12
IS  - 3
SP  - 137-145
EP  - 137-145
PB  - Faculty of Health and Social Care, University of South Bohemia
SN  - 1214021X
KW  - Nanoparticle
KW  - nanosilver
KW  - sonodynamic therapy
KW  - Ultrasound
UR  - http://www.sciencedirect.com/science/article/pii/S1214021X14000283
N2  - Antibacterial activity of silver nanoparticles is widely known and used. The effect of application of therapeutical ultrasonic field in the presence of silver nanoparticles <100 nm was examined on human ovarian carcinoma cell A2780. The cell's viability was examined by MTT assay and by life-time microscopy. The presence of nanoparticles in the cell was examined by using electron transmission microscopy. Experimental results indicate a significant decrease of viability of cell, which was affected by the combined action of ultrasound field and silver nanoparticles, compared to the separate exposure of silver nanoparticles or ultrasonic field. The experiments showed a significant effect of succession of application of these two factors. The presence of nanoparticles inside cells after incubation was showed. The results show the possibility of using of ultrasonic field as a factor that can significantly affect cell viability in the presence of silver nanoparticles.
ER  -

BERNARD, Vladan, Vojtěch MORNSTEIN, Josef JAROŠ, Miroslava SEDLÁČKOVÁ a Jiřina ŠKORPÍKOVÁ. Combined effect of silver nanoparticles and therapeutical ultrasound on ovarian carcinoma cells A2780. \textit{Journal of Applied Biomedicine}. České Budějovice: Faculty of Health and Social Care, University of South Bohemia, 2014, roč.~12, č.~3, s.~137-145. ISSN~1214-021X. Dostupné z: https://dx.doi.org/10.1016/j.jab.2014.01.002.

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