A Pencil Graphite Electrode In Situ Modified by Monovalent
Copper: a Promising Tool for the Determination of
Methylxanthines

J 2014

A Pencil Graphite Electrode In Situ Modified by Monovalent Copper: a Promising Tool for the Determination of Methylxanthines

NAVRÁTIL, Rudolf; František JELEN; Yasin Ugur KAYRAN a Libuše TRNKOVÁ

Základní údaje

Originální název

A Pencil Graphite Electrode In Situ Modified by Monovalent Copper: a Promising Tool for the Determination of Methylxanthines

Autoři

NAVRÁTIL, Rudolf; František JELEN; Yasin Ugur KAYRAN a Libuše TRNKOVÁ

Vydání

Electroanalysis, WEINHEIM, WILEY-VCH Verlag GmbH, 2014, 1040-0397

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10403 Physical chemistry

Stát vydavatele

Německo

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.138

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/14:00075812

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova anglicky

Methylxanthines; Pencil graphite electrode; Elimination voltammetry; Copper-purine complexes

Štítky

AKR, rivok

Změněno: 23. 4. 2020 17:49, Mgr. Marie Novosadová Šípková, DiS.

Anotace

V originále

A pencil graphite electrode (PeGE) exhibits a promising tool for the electrochemical analysis of xanthine (Xan) and its N-methyl derivatives (1-, 3-, 7- and 9-mXan). The changes in their level in blood, serum, urine, as products of purine catabolism, can indicate the development of some diseases. Sensitivity-enhanced voltammetric detection of mXans was achieved by forming of complex with Cu(I) and application of elimination procedure. The Cu(I)-mXan complex was identified by means of titration of electrochemically produced cuprous ions by mXan. Our approach enables separation of overlapped mXan oxidation signals. Based on the obtained results, we found that the effect of methyl group position on the xanthine skeleton was significant and it was also discussed.

Návaznosti

ED1.1.00/02.0068, projekt VaV

Název: CEITEC - central european institute of technology

LH13053, projekt VaV

Název: Chemická a elektrochemická analýza purinových derivátů a jejich komplexů s mědí (Akronym: CECAP)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Chemická a elektrochemická analýza purinových derivátů

Citovat

NAVRÁTIL, Rudolf; František JELEN; Yasin Ugur KAYRAN a Libuše TRNKOVÁ. A Pencil Graphite Electrode In Situ Modified by Monovalent Copper: a Promising Tool for the Determination of Methylxanthines. Electroanalysis. WEINHEIM: WILEY-VCH Verlag GmbH, 2014, roč. 26, č. 5, s. 952-961. ISSN 1040-0397. Dostupné z: https://doi.org/10.1002/elan.201400017.

@article{1187087,
   author = {Navrátil, Rudolf and Jelen, František and Kayran, Yasin Ugur and Trnková, Libuše},
   article_location = {WEINHEIM},
   article_number = {5},
   doi = {https://doi.org/10.1002/elan.201400017},
   keywords = {Methylxanthines; Pencil graphite electrode; Elimination voltammetry; Copper-purine complexes},
   language = {eng},
   issn = {1040-0397},
   journal = {Electroanalysis},
   title = {A Pencil Graphite Electrode In Situ Modified by Monovalent Copper: a Promising Tool for the Determination of Methylxanthines},
   url = {http://dx.doi.org/10.1002/elan.201400017},
   volume = {26},
   year = {2014}
}

TY  - JOUR
ID  - 1187087
AU  - Navrátil, Rudolf - Jelen, František - Kayran, Yasin Ugur - Trnková, Libuše
PY  - 2014
TI  - A Pencil Graphite Electrode In Situ Modified by Monovalent Copper: a Promising Tool for the Determination of Methylxanthines
JF  - Electroanalysis
VL  - 26
IS  - 5
SP  - 952-961
EP  - 952-961
PB  - WILEY-VCH Verlag GmbH
SN  - 10400397
KW  - Methylxanthines
KW  - Pencil graphite electrode
KW  - Elimination voltammetry
KW  - Copper-purine complexes
UR  - http://dx.doi.org/10.1002/elan.201400017
L2  - http://dx.doi.org/10.1002/elan.201400017
N2  - A pencil graphite electrode (PeGE) exhibits a promising tool for the electrochemical analysis of xanthine (Xan) and its N-methyl derivatives (1-, 3-, 7- and 9-mXan). The changes in their level in blood, serum, urine, as products of purine catabolism, can indicate the development of some diseases. Sensitivity-enhanced voltammetric detection of mXans was achieved by forming of complex with Cu(I) and application of elimination procedure. The Cu(I)-mXan complex was identified by means of titration of electrochemically produced cuprous ions by mXan. Our approach enables separation of overlapped mXan oxidation signals. Based on the obtained results, we found that the effect of methyl group position on the xanthine skeleton was significant and it was also discussed.
ER  -

NAVRÁTIL, Rudolf; František JELEN; Yasin Ugur KAYRAN a Libuše TRNKOVÁ. A Pencil Graphite Electrode In Situ Modified by Monovalent Copper: a Promising Tool for the Determination of Methylxanthines. \textit{Electroanalysis}. WEINHEIM: WILEY-VCH Verlag GmbH, 2014, roč.~26, č.~5, s.~952-961. ISSN~1040-0397. Dostupné z: https://doi.org/10.1002/elan.201400017.

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