Sleep apnea prevalence in acute myocardial infarction - The
Sleep Apnea in Post-acute Myocardial Infarction Patients
(SAPAMI) Study

J 2014

Sleep apnea prevalence in acute myocardial infarction - The Sleep Apnea in Post-acute Myocardial Infarction Patients (SAPAMI) Study

LUDKA, Ondřej; Radka ŠTĚPÁNOVÁ; Martina VYSKOCILOVA; Lujza ZIKMUND GALKOVÁ; Monika MIKOLÁŠKOVÁ et al.

Základní údaje

Originální název

Sleep apnea prevalence in acute myocardial infarction - The Sleep Apnea in Post-acute Myocardial Infarction Patients (SAPAMI) Study

Autoři

Vydání

International Journal of Cardiology, Clare, Elsevier Ireland Ltd. 2014, 0167-5273

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Irsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 4.036

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/14:00077695

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

Sleep apnea; Acute myocardial infarction; Prevalence; Day-night variation

Štítky

EL OK

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 9. 12. 2014 11:25, Soňa Böhmová

Anotace

V originále

Background: While sleep apnea (SA) might be a modifiable cardiovascular risk factor, recent data suggest that SA is severely underdiagnosed in patients after acute myocardial infarction (MI). There is limited evidence about day-night variation of onset of MI on dependence of having SA. We therefore investigated the prevalence of SA and examined the day-night variation of onset of MI in acute MI patients. Methods: We prospectively studied 782 consecutive patients admitted to the hospital with the diagnosis of acute MI. All subjects underwent sleep evaluations using a portable device after at least 48 h post-admission. Using the apnea-hypopnea index (AHI), groups were defined as patients without SA (<5 events/h), mild SA (5-15 events/h), moderate SA (15-30 events/h), and severe SA (>= 30 events/h). Results: Almost all patients (98%) underwent urgent coronary angiography and 91% of patients underwent primary PCI. Using a threshold of AHI >= 5 events/h, SA was present in 65.7% of patients after acute MI. Mild SA was present in 32.6%, moderate in 20.4% and severe in 12.7%. The day-night variation in the onset of MI in all groups of SA patients was similar to that observed in non-SA patients. From 6 AM to 12 PM, the frequency of MI was higher in both SA and non-SA patients, as compared to the interval from 12 AM to 6 AM (all p < 0.05). Conclusion: There is a high prevalence of SA in patients presenting with acute MI. Peak time of MI onset in SA patients was between 6 AM and noon, similar to that in the general population. Whether diagnosis and treatment of SA after MI will significantly improve outcomes in these patients remains to be determined.

Citovat

LUDKA, Ondřej; Radka ŠTĚPÁNOVÁ; Martina VYSKOCILOVA; Lujza ZIKMUND GALKOVÁ; Monika MIKOLÁŠKOVÁ; Milos BELEHRAD; Jana KOSTALOVA; Zuzana MIHALOVÁ; Adéla DROZDOVÁ; Jiří HLÁSENSKÝ; Michal GACÍK; Lucie PUDILOVÁ; Tereza MIKUŠOVÁ; Blanka FISCHEROVÁ; Fatima SERT-KUNIYOSHI; Virend K. SOMERS; Jindřich ŠPINAR a Tomáš KÁRA. Sleep apnea prevalence in acute myocardial infarction - The Sleep Apnea in Post-acute Myocardial Infarction Patients (SAPAMI) Study. International Journal of Cardiology. Clare: Elsevier Ireland Ltd., 2014, roč. 176, č. 1, s. 13-19. ISSN 0167-5273. Dostupné z: https://doi.org/10.1016/j.ijcard.2014.06.020.

@article{1212404,
   author = {Ludka, Ondřej and Štěpánová, Radka and Vyskocilova, Martina and Zikmund Galková, Lujza and Mikolášková, Monika and Belehrad, Milos and Kostalova, Jana and Mihalová, Zuzana and Drozdová, Adéla and Hlásenský, Jiří and Gacík, Michal and Pudilová, Lucie and Mikušová, Tereza and Fischerová, Blanka and SertandKuniyoshi, Fatima and Somers, Virend K. and Špinar, Jindřich and Kára, Tomáš},
   article_location = {Clare},
   article_number = {1},
   doi = {https://doi.org/10.1016/j.ijcard.2014.06.020},
   keywords = {Sleep apnea; Acute myocardial infarction; Prevalence; Day-night variation},
   language = {eng},
   issn = {0167-5273},
   journal = {International Journal of Cardiology},
   title = {Sleep apnea prevalence in acute myocardial infarction - The Sleep Apnea in Post-acute Myocardial Infarction Patients (SAPAMI) Study},
   volume = {176},
   year = {2014}
}

TY  - JOUR
ID  - 1212404
AU  - Ludka, Ondřej - Štěpánová, Radka - Vyskocilova, Martina - Zikmund Galková, Lujza - Mikolášková, Monika - Belehrad, Milos - Kostalova, Jana - Mihalová, Zuzana - Drozdová, Adéla - Hlásenský, Jiří - Gacík, Michal - Pudilová, Lucie - Mikušová, Tereza - Fischerová, Blanka - Sert-Kuniyoshi, Fatima - Somers, Virend K. - Špinar, Jindřich - Kára, Tomáš
PY  - 2014
TI  - Sleep apnea prevalence in acute myocardial infarction - The Sleep Apnea in Post-acute Myocardial Infarction Patients (SAPAMI) Study
JF  - International Journal of Cardiology
VL  - 176
IS  - 1
SP  - 13-19
EP  - 13-19
PB  - Elsevier Ireland Ltd.
SN  - 01675273
KW  - Sleep apnea
KW  - Acute myocardial infarction
KW  - Prevalence
KW  - Day-night variation
N2  - Background: While sleep apnea (SA) might be a modifiable cardiovascular risk factor, recent data suggest that SA is severely underdiagnosed in patients after acute myocardial infarction (MI). There is limited evidence about day-night variation of onset of MI on dependence of having SA. We therefore investigated the prevalence of SA and examined the day-night variation of onset of MI in acute MI patients. Methods: We prospectively studied 782 consecutive patients admitted to the hospital with the diagnosis of acute MI. All subjects underwent sleep evaluations using a portable device after at least 48 h post-admission. Using the apnea-hypopnea index (AHI), groups were defined as patients without SA (<5 events/h), mild SA (5-15 events/h), moderate SA (15-30 events/h), and severe SA (>= 30 events/h). Results: Almost all patients (98%) underwent urgent coronary angiography and 91% of patients underwent primary PCI. Using a threshold of AHI >= 5 events/h, SA was present in 65.7% of patients after acute MI. Mild SA was present in 32.6%, moderate in 20.4% and severe in 12.7%. The day-night variation in the onset of MI in all groups of SA patients was similar to that observed in non-SA patients. From 6 AM to 12 PM, the frequency of MI was higher in both SA and non-SA patients, as compared to the interval from 12 AM to 6 AM (all p < 0.05). Conclusion: There is a high prevalence of SA in patients presenting with acute MI. Peak time of MI onset in SA patients was between 6 AM and noon, similar to that in the general population. Whether diagnosis and treatment of SA after MI will significantly improve outcomes in these patients remains to be determined.
ER  -

LUDKA, Ondřej; Radka ŠTĚPÁNOVÁ; Martina VYSKOCILOVA; Lujza ZIKMUND GALKOVÁ; Monika MIKOLÁŠKOVÁ; Milos BELEHRAD; Jana KOSTALOVA; Zuzana MIHALOVÁ; Adéla DROZDOVÁ; Jiří HLÁSENSKÝ; Michal GACÍK; Lucie PUDILOVÁ; Tereza MIKUŠOVÁ; Blanka FISCHEROVÁ; Fatima SERT-KUNIYOSHI; Virend K. SOMERS; Jindřich ŠPINAR a Tomáš KÁRA. Sleep apnea prevalence in acute myocardial infarction - The Sleep Apnea in Post-acute Myocardial Infarction Patients (SAPAMI) Study. \textit{International Journal of Cardiology}. Clare: Elsevier Ireland Ltd., 2014, roč.~176, č.~1, s.~13-19. ISSN~0167-5273. Dostupné z: https://doi.org/10.1016/j.ijcard.2014.06.020.

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