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@article{1216513, author = {Lambert, Lukas and Danes, Jan and Jahoda, Jiri and Masek, Martin and Lisy, Jiri and Ouředníček, Petr}, article_location = {London}, article_number = {5}, doi = {http://dx.doi.org/10.1177/0284185114533683}, keywords = {Colonography; polyp; low-dose; iterative reconstruction; computed tomography; colon}, language = {eng}, issn = {0284-1851}, journal = {Acta Radiologica}, title = {Submilisievert ultralow-dose CT colonography using iterative reconstruction technique: a feasibility study}, volume = {56}, year = {2015} }
TY - JOUR ID - 1216513 AU - Lambert, Lukas - Danes, Jan - Jahoda, Jiri - Masek, Martin - Lisy, Jiri - Ouředníček, Petr PY - 2015 TI - Submilisievert ultralow-dose CT colonography using iterative reconstruction technique: a feasibility study JF - Acta Radiologica VL - 56 IS - 5 SP - 517-525 EP - 517-525 PB - SAGE Publications Inc. SN - 02841851 KW - Colonography KW - polyp KW - low-dose KW - iterative reconstruction KW - computed tomography KW - colon N2 - Background: Computed tomography (CT) colonography is a well established modality for the examination of symptomatic patients as well as in screening. Recent technical advances in improving image quality by iterative reconstruction contribute to the reduction of the radiation dose which is a major concern in CT imaging. Purpose: To evaluate image quality of ultralow-dose submilisievert CT colonography using hybrid iterative reconstruction technique. Material and Methods: Sixteen patients underwent contrast-enhanced CT colonography with standard protocol in supine position and ultralow-dose protocol in prone position. Ultralow-dose datasets were reconstructed with filtered back projection and an advanced hybrid iterative reconstruction technique. Two radiologists independently evaluated 96 colonic segments for image quality in the endoluminal view and axial thin sections. Colonic distension, smoothness of colonic wall and distortion of folds in the endoluminal view, sharpness of colonic wall delineation, perceived image noise, and presence of photon starvation artifact were rated on a five-point scale. Intraluminal noise expressed as standard deviation of Hounsfield density was measured in all segments. Results: The mean radiation dose was 0.42 mSv and 5.48 mSv in prone and supine scans, respectively. All distended segments were rated evaluable in standard dose and ultralow-dose series reconstructed with the iterative reconstruction technique, whereas in 61% segments image quality was rated poor or unacceptable in ultralow-dose series where filtered back projection was used with worst ratings in the rectum and the sigmoid colon. Conclusion: This pilot study shows that iterative reconstruction technique is a feasible method to decrease the radiation dose from CT colonography for both positions below 1mSv. Further investigations of larger scale need to be done to clarify, whether such a low radiation dose would influence the detection of polyps. ER -
LAMBERT, Lukas, Jan DANES, Jiri JAHODA, Martin MASEK, Jiri LISY a Petr OUŘEDNÍČEK. Submilisievert ultralow-dose CT colonography using iterative reconstruction technique: a feasibility study. \textit{Acta Radiologica}. London: SAGE Publications Inc., 2015, roč.~56, č.~5, s.~517-525. ISSN~0284-1851. Dostupné z: https://dx.doi.org/10.1177/0284185114533683.
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