Evaluation of three purely polypropylene meshes of different
pore sizes in an onlay position in a New Zealand white rabbit
model

J 2014

Evaluation of three purely polypropylene meshes of different pore sizes in an onlay position in a New Zealand white rabbit model

JEŘÁBEK, Jiří; Tomáš NOVOTNÝ; Karel VESELÝ; Jan CAGAŠ; Václav JEDLIČKA et al.

Základní údaje

Originální název

Evaluation of three purely polypropylene meshes of different pore sizes in an onlay position in a New Zealand white rabbit model

Autoři

JEŘÁBEK, Jiří; Tomáš NOVOTNÝ; Karel VESELÝ; Jan CAGAŠ; Václav JEDLIČKA; Petr VLČEK a Ivan ČAPOV

Vydání

Hernia, New York, Springer, 2014, 1265-4906

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30200 3.2 Clinical medicine

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 2.050

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/14:00078365

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

Hernia; Polypropylene mesh; Pore size; Shrinkage; Abdominal wall compliance; Foreign body reaction

Štítky

EL OK

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 4. 2. 2015 17:16, Ing. Mgr. Věra Pospíšilíková

Anotace

V originále

The aim of the study was to evaluate the influence of the pore size of a polypropylene mesh on the shrinkage and elasticity of the mesh-tissue complex and the inflammatory reaction to the implant in an open onlay hernia repair. Twenty-one 10 x 10 cm samples of polypropylene meshes of a different pore size (3.0 x 2.8 mm-PP3, 1.0 x 0.8 mm-PP1 and 0.6 x 0.5 mm-PP.5) were implanted in an onlay position in 21 New Zealand white rabbits. After 90 days of implantation the shrinkage, elasticity and foreign body reaction (FBR) were assessed. The shrinkage of PP3 was 30.6 +/- A 4.3 %, PP1 49.3 +/- A 2.9 % and PP.5 49.5 +/- A 2.6 %. The shrinkage of PP3 was significantly lower (PP3 x PP1 p = 0.007, PP3 x PP.5 p = 0.005), PP1 and PP.5 were similar. The elasticity was similar. The strength of FBR in mesh pores was similar. The width of foreign body granuloma layers at the mesh-tissue interface was significantly reduced with increasing pore size (inner: PP3 10.1 +/- A 1.2; PP1 12.5 +/- A 2.9; PP.5 17.4 +/- A 5.2 and outer: PP3 21.2 +/- A 2.5; PP1 30.6 +/- A 6.3; PP.5 60.4 +/- A 14.9). All differences between the widths of granuloma layers were statistically significant (p < 0.010). One animal (PP1) was excluded because of a mesh infection. Implantation of polypropylene mesh of a pore size of 3 mm in an onlay position is associated with a significant reduction of shrinkage in comparison to a 1 mm pore lightweight and 0.5 mm pore heavyweight mesh. A pore size increase to 3 mm is not sufficient for an improvement of mesh-tissue complex elasticity in comparison to a 1 mm pore lightweight and 0.5 mm heavyweight mesh. Polypropylene mesh with enlarged pores to 3 mm is associated with a similar strength of FBR in mesh pores and a reduced foreign body granuloma in comparison to a 1 mm pore lightweight and 0.5 mm pore heavyweight mesh.

Citovat

JEŘÁBEK, Jiří; Tomáš NOVOTNÝ; Karel VESELÝ; Jan CAGAŠ; Václav JEDLIČKA; Petr VLČEK a Ivan ČAPOV. Evaluation of three purely polypropylene meshes of different pore sizes in an onlay position in a New Zealand white rabbit model. Hernia. New York: Springer, 2014, roč. 18, č. 6, s. 855-864. ISSN 1265-4906. Dostupné z: https://doi.org/10.1007/s10029-014-1278-9.

@article{1216678,
   author = {Jeřábek, Jiří and Novotný, Tomáš and Veselý, Karel and Cagaš, Jan and Jedlička, Václav and Vlček, Petr and Čapov, Ivan},
   article_location = {New York},
   article_number = {6},
   doi = {https://doi.org/10.1007/s10029-014-1278-9},
   keywords = {Hernia; Polypropylene mesh; Pore size; Shrinkage; Abdominal wall compliance; Foreign body reaction},
   language = {eng},
   issn = {1265-4906},
   journal = {Hernia},
   title = {Evaluation of three purely polypropylene meshes of different pore sizes in an onlay position in a New Zealand white rabbit model},
   volume = {18},
   year = {2014}
}

TY  - JOUR
ID  - 1216678
AU  - Jeřábek, Jiří - Novotný, Tomáš - Veselý, Karel - Cagaš, Jan - Jedlička, Václav - Vlček, Petr - Čapov, Ivan
PY  - 2014
TI  - Evaluation of three purely polypropylene meshes of different pore sizes in an onlay position in a New Zealand white rabbit model
JF  - Hernia
VL  - 18
IS  - 6
SP  - 855-864
EP  - 855-864
PB  - Springer
SN  - 12654906
KW  - Hernia
KW  - Polypropylene mesh
KW  - Pore size
KW  - Shrinkage
KW  - Abdominal wall compliance
KW  - Foreign body reaction
N2  - The aim of the study was to evaluate the influence of the pore size of a polypropylene mesh on the shrinkage and elasticity of the mesh-tissue complex and the inflammatory reaction to the implant in an open onlay hernia repair. Twenty-one 10 x 10 cm samples of polypropylene meshes of a different pore size (3.0 x 2.8 mm-PP3, 1.0 x 0.8 mm-PP1 and 0.6 x 0.5 mm-PP.5) were implanted in an onlay position in 21 New Zealand white rabbits. After 90 days of implantation the shrinkage, elasticity and foreign body reaction (FBR) were assessed. The shrinkage of PP3 was 30.6 +/- A 4.3 %, PP1 49.3 +/- A 2.9 % and PP.5 49.5 +/- A 2.6 %. The shrinkage of PP3 was significantly lower (PP3 x PP1 p = 0.007, PP3 x PP.5 p = 0.005), PP1 and PP.5 were similar. The elasticity was similar. The strength of FBR in mesh pores was similar. The width of foreign body granuloma layers at the mesh-tissue interface was significantly reduced with increasing pore size (inner: PP3 10.1 +/- A 1.2; PP1 12.5 +/- A 2.9; PP.5 17.4 +/- A 5.2 and outer: PP3 21.2 +/- A 2.5; PP1 30.6 +/- A 6.3; PP.5 60.4 +/- A 14.9). All differences between the widths of granuloma layers were statistically significant (p < 0.010). One animal (PP1) was excluded because of a mesh infection. Implantation of polypropylene mesh of a pore size of 3 mm in an onlay position is associated with a significant reduction of shrinkage in comparison to a 1 mm pore lightweight and 0.5 mm pore heavyweight mesh. A pore size increase to 3 mm is not sufficient for an improvement of mesh-tissue complex elasticity in comparison to a 1 mm pore lightweight and 0.5 mm heavyweight mesh. Polypropylene mesh with enlarged pores to 3 mm is associated with a similar strength of FBR in mesh pores and a reduced foreign body granuloma in comparison to a 1 mm pore lightweight and 0.5 mm pore heavyweight mesh.
ER  -

JEŘÁBEK, Jiří; Tomáš NOVOTNÝ; Karel VESELÝ; Jan CAGAŠ; Václav JEDLIČKA; Petr VLČEK a Ivan ČAPOV. Evaluation of three purely polypropylene meshes of different pore sizes in an onlay position in a New Zealand white rabbit model. \textit{Hernia}. New York: Springer, 2014, roč.~18, č.~6, s.~855-864. ISSN~1265-4906. Dostupné z: https://doi.org/10.1007/s10029-014-1278-9.

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