Pupilární reakce na barevné podněty

SKORKOVSKÁ, Karolína; F. MAEDA; C. KELBSCH; T. PETERS; B. WILHELM a H. WILHELM. Pupilární reakce na barevné podněty. Česká a Slovenská neurologie a neurochirurgie. Praha: Česká lékařská společnost J.E. Purkyně, 2014, roč. 77, č. 3, s. 334-338. ISSN 1210-7859.

Základní údaje

Originální název

Pupilární reakce na barevné podněty

Název anglicky

Pupillary Response to Chromatic Stimuli

Autoři

SKORKOVSKÁ, Karolína; F. MAEDA; C. KELBSCH; T. PETERS; B. WILHELM a H. WILHELM

Vydání

Česká a Slovenská neurologie a neurochirurgie, Praha, Česká lékařská společnost J.E. Purkyně, 2014, 1210-7859

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Další údaje

Jazyk

čeština

Typ výsledku

Článek v odborném periodiku

Obor

30200 3.2 Clinical medicine

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 0.165

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/14:00078374

Organizační jednotka

Lékařská fakulta

UT WoS

000336563200010

Klíčová slova anglicky

pupillary reflex; melanopsin; photoreceptor cells

Štítky

EL OK

Příznaky

Mezinárodní význam, Recenzováno

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Anotace

V originále

Aim of study: To compare chromatic pupillary responses in a group of healthy subjects and to determine if this method can be used for assessing outer and inner retinal function. Material and methods: The study group consisted of 17 healthy subjects. Subjects were tested with a chromatic pupillometer. The parameters of the stimulus were as follows: intensity 28 lx, duration 4 sec, and color blue (420 +/- 20 nm) and red (605 +/- 20 nm). The examined pupil parameters were baseline pupil diameter, maximal constriction time, relative amplitude at maximal constriction, at 3 sec after stimulus onset, at stimulus offset, at 3 sec after stimulus offset and at 7 sec after stimulus offset. Pupil response parameters to red and blue light were evaluated by paired t-test. Results: Except for the baseline pupil diameter (p = 0.148), there was a significant difference in all pupil response parameters to red and blue light (p = 0.001). With blue light, the relative amplitude was significantly greater and the time to maximal pupil constriction significantly longer compared to red light for all tested time points. Blue light evoked "sustained" pupil contraction, while red light rather induced "transient" contraction. Conclusions: Our examination protocol allowed us to unmask differences in pupil response to red and blue light in healthy subjects and to confirm involvement of the melanopsin retinal ganglion cells in the pupil light reflex, particularly with blue light. Chromatic pupillography appears to be a highly sensitive method for objective evaluation of the outer and inner retina function.

Anglicky

Aim of study: To compare chromatic pupillary responses in a group of healthy subjects and to determine if this method can be used for assessing outer and inner retinal function. Material and methods: The study group consisted of 17 healthy subjects. Subjects were tested with a chromatic pupillometer. The parameters of the stimulus were as follows: intensity 28 lx, duration 4 sec, and color blue (420 +/- 20 nm) and red (605 +/- 20 nm). The examined pupil parameters were baseline pupil diameter, maximal constriction time, relative amplitude at maximal constriction, at 3 sec after stimulus onset, at stimulus offset, at 3 sec after stimulus offset and at 7 sec after stimulus offset. Pupil response parameters to red and blue light were evaluated by paired t-test. Results: Except for the baseline pupil diameter (p = 0.148), there was a significant difference in all pupil response parameters to red and blue light (p = 0.001). With blue light, the relative amplitude was significantly greater and the time to maximal pupil constriction significantly longer compared to red light for all tested time points. Blue light evoked "sustained" pupil contraction, while red light rather induced "transient" contraction. Conclusions: Our examination protocol allowed us to unmask differences in pupil response to red and blue light in healthy subjects and to confirm involvement of the melanopsin retinal ganglion cells in the pupil light reflex, particularly with blue light. Chromatic pupillography appears to be a highly sensitive method for objective evaluation of the outer and inner retina function.