Clinical Management of Pregnancy in Women with Goodpasture
Syndrome

J 2015

Clinical Management of Pregnancy in Women with Goodpasture Syndrome

HUSER, Martin; Kristýna WÁGNEROVÁ; Petr JANKŮ; Lenka MALÁSKOVÁ; Petr ŠTOURAČ et al.

Základní údaje

Originální název

Clinical Management of Pregnancy in Women with Goodpasture Syndrome

Autoři

HUSER, Martin; Kristýna WÁGNEROVÁ; Petr JANKŮ ; Lenka MALÁSKOVÁ a Petr ŠTOURAČ

Vydání

Gynecologic and Obstetrics Investigation, Basel, KARGER, 2015, 0378-7346

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30214 Obstetrics and gynaecology

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 1.672

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/15:00082336

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

Goodpasture syndrome; Pregnancy; Complications; Renal biopsy; Abortion

Štítky

EL OK

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 14. 4. 2015 11:25, Ing. Mgr. Věra Pospíšilíková

Anotace

V originále

Background/Aims: Goodpasture syndrome (GS) is an autoimmune disease affecting mainly the kidneys and lungs. This review article focuses on GS occurring during pregnancy, which can seriously threaten the lives of both mother and fetus. We summarize the current clinical diagnosis and management of GS in pregnancy. Methods: A profound literature search was carried out to review all published articles or case studies reporting on GS in pregnancy. We extracted the following data from each case: patient age, parity, gestational age, therapy of GS during pregnancy, pregnancy outcome, neonatal outcome, mode of delivery, and the patient's kidney status. We describe in detail how a recent case of GS diagnosed in pregnancy was successfully treated. Results: A review of the available literature revealed 4 cases of GS in pregnancy. The average patient age was 29.3 +/- 2.5 years, and most were primiparous, with an average parity of 1.3 +/- 1.5. The average gestational age at the time of diagnosis was 12.5 +/- 5.9 weeks. The therapies of GS during pregnancy were remarkably varied. Furthermore, the neonatal outcomes were also quite individual among the observed cases. Conclusion:The occurrence of GS during pregnancy is very rare. This unusual pregnancy complication is associated with significant maternal and fetal morbidity. The management of GS during pregnancy requires intensive care and multidisciplinary cooperation.

Citovat

HUSER, Martin; Kristýna WÁGNEROVÁ; Petr JANKŮ; Lenka MALÁSKOVÁ a Petr ŠTOURAČ. Clinical Management of Pregnancy in Women with Goodpasture Syndrome. Gynecologic and Obstetrics Investigation. Basel: KARGER, 2015, roč. 79, č. 2, s. 73-77. ISSN 0378-7346. Dostupné z: https://doi.org/10.1159/000369998.

@article{1220112,
   author = {Huser, Martin and Wágnerová, Kristýna and Janků, Petr and Malásková, Lenka and Štourač, Petr},
   article_location = {Basel},
   article_number = {2},
   doi = {https://doi.org/10.1159/000369998},
   keywords = {Goodpasture syndrome; Pregnancy; Complications; Renal biopsy; Abortion},
   language = {eng},
   issn = {0378-7346},
   journal = {Gynecologic and Obstetrics Investigation},
   title = {Clinical Management of Pregnancy in Women with Goodpasture Syndrome},
   volume = {79},
   year = {2015}
}

TY  - JOUR
ID  - 1220112
AU  - Huser, Martin - Wágnerová, Kristýna - Janků, Petr - Malásková, Lenka - Štourač, Petr
PY  - 2015
TI  - Clinical Management of Pregnancy in Women with Goodpasture Syndrome
JF  - Gynecologic and Obstetrics Investigation
VL  - 79
IS  - 2
SP  - 73-77
EP  - 73-77
PB  - KARGER
SN  - 03787346
KW  - Goodpasture syndrome
KW  - Pregnancy
KW  - Complications
KW  - Renal biopsy
KW  - Abortion
N2  - Background/Aims: Goodpasture syndrome (GS) is an autoimmune disease affecting mainly the kidneys and lungs. This review article focuses on GS occurring during pregnancy, which can seriously threaten the lives of both mother and fetus. We summarize the current clinical diagnosis and management of GS in pregnancy. Methods: A profound literature search was carried out to review all published articles or case studies reporting on GS in pregnancy. We extracted the following data from each case: patient age, parity, gestational age, therapy of GS during pregnancy, pregnancy outcome, neonatal outcome, mode of delivery, and the patient's kidney status. We describe in detail how a recent case of GS diagnosed in pregnancy was successfully treated. Results: A review of the available literature revealed 4 cases of GS in pregnancy. The average patient age was 29.3 +/- 2.5 years, and most were primiparous, with an average parity of 1.3 +/- 1.5. The average gestational age at the time of diagnosis was 12.5 +/- 5.9 weeks. The therapies of GS during pregnancy were remarkably varied. Furthermore, the neonatal outcomes were also quite individual among the observed cases. Conclusion:The occurrence of GS during pregnancy is very rare. This unusual pregnancy complication is associated with significant maternal and fetal morbidity. The management of GS during pregnancy requires intensive care and multidisciplinary cooperation.
ER  -

HUSER, Martin; Kristýna WÁGNEROVÁ; Petr JANKŮ; Lenka MALÁSKOVÁ a Petr ŠTOURAČ. Clinical Management of Pregnancy in Women with Goodpasture Syndrome. \textit{Gynecologic and Obstetrics Investigation}. Basel: KARGER, 2015, roč.~79, č.~2, s.~73-77. ISSN~0378-7346. Dostupné z: https://doi.org/10.1159/000369998.

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