J 2014

Relation of chronic obstructive pulmonary disease to atrial and ventricular arrhythmias

KONEČNÝ, Tomáš, Jae Yoon PARK, Kiran R. SOMERS, Dana KONECNY, Marek ORBAN et. al.

Základní údaje

Originální název

Relation of chronic obstructive pulmonary disease to atrial and ventricular arrhythmias

Autoři

KONEČNÝ, Tomáš (203 Česká republika, garant, domácí), Jae Yoon PARK (840 Spojené státy), Kiran R. SOMERS (840 Spojené státy), Dana KONECNY (203 Česká republika), Marek ORBAN (203 Česká republika, domácí), Filip SOUČEK (203 Česká republika, domácí), Kenneth O. PARKER (840 Spojené státy), Paul D. SCANLON (840 Spojené státy), Samuel J. ASIRVATHAM (840 Spojené státy), Peter A. BRADY (840 Spojené státy) a Charanjit S. RIHAL (840 Spojené státy)

Vydání

American Journal of Cardiology, Bridgewater, EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC, 2014, 0002-9149

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Impakt faktor

Impact factor: 3.276

Kód RIV

RIV/00216224:14110/14:00079108

Organizační jednotka

Lékařská fakulta

UT WoS

000338689100016

Klíčová slova anglicky

POPULATION-BASED COHORT; CHRONIC LUNG-DISEASE; CARDIOVASCULAR-DISEASE; CARDIAC-ARRHYTHMIAS; CATHETER ABLATION; RISK-FACTORS; COPD; FIBRILLATION; MORTALITY; HEALTH

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 24. 4. 2015 13:21, Ing. Mgr. Věra Pospíšilíková

Anotace

V originále

Chronic obstructive pulmonary disease (COPD) is associated with increased cardiovascular morbidity and mortality, yet the exact pathophysiological links remain unclear. Whether the presence and severity of COPD are associated with atrial or ventricular arrhythmias recorded on continuous electrocardiographic monitoring is unknown. We identified consecutive adult patients who underwent clinically indicated pulmonary function testing as well as 24-hour Holter monitoring at the Mayo Clinic, Rochester, from 2000 to 2009. Demographic data and relevant co-morbidities were gathered from the electronic medical record; severity of COPD was classified according to the GOLD classification, and arrhythmias were classified in concordance with the current clinical guidelines. From 7,441 patients who were included (age 64 +/- 16 years, 49% woman, 92% Caucasian), COPD was diagnosed in 3,121 (41.9%). Compared with those without COPD, the presence and severity of COPD were associated with increased likelihood of atrial fibrillation/atrial flutter (AF/AFL; 23.3% vs 11.0%, respectively, p <0.0001), nonsustained ventricular tachycardia (NSVT; 13.0% vs 5.9%, respectively, p <0.0001), and sustained ventricular tachycardia (0.9% vs 1.6%, respectively, p <0.0001). COPD remained a significant predictor of AF/AFL and NSVT (p <0.0001 and p <0.0001, respectively) after adjusting for age, gender, tobacco use, obesity, hypertension, coronary artery disease, heart failure, diabetes, anemia, cancer, chronic kidney disease, and rate/rhythm control medications. In conclusion, the independent association between the presence and severity of COPD and arrhythmias (AF/AFL and NSVT) provides further insight into the markedly increased cardiovascular mortality of patients with COPD. Further studies should explore which anti-arrhythmic strategies would best apply to the patients with COPD.