2014
Relation of chronic obstructive pulmonary disease to atrial and ventricular arrhythmias
KONEČNÝ, Tomáš, Jae Yoon PARK, Kiran R. SOMERS, Dana KONECNY, Marek ORBAN et. al.Základní údaje
Originální název
Relation of chronic obstructive pulmonary disease to atrial and ventricular arrhythmias
Autoři
KONEČNÝ, Tomáš (203 Česká republika, garant, domácí), Jae Yoon PARK (840 Spojené státy), Kiran R. SOMERS (840 Spojené státy), Dana KONECNY (203 Česká republika), Marek ORBAN (203 Česká republika, domácí), Filip SOUČEK (203 Česká republika, domácí), Kenneth O. PARKER (840 Spojené státy), Paul D. SCANLON (840 Spojené státy), Samuel J. ASIRVATHAM (840 Spojené státy), Peter A. BRADY (840 Spojené státy) a Charanjit S. RIHAL (840 Spojené státy)
Vydání
American Journal of Cardiology, Bridgewater, EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC, 2014, 0002-9149
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
30201 Cardiac and Cardiovascular systems
Stát vydavatele
Spojené státy
Utajení
není předmětem státního či obchodního tajemství
Odkazy
Impakt faktor
Impact factor: 3.276
Kód RIV
RIV/00216224:14110/14:00079108
Organizační jednotka
Lékařská fakulta
UT WoS
000338689100016
Klíčová slova anglicky
POPULATION-BASED COHORT; CHRONIC LUNG-DISEASE; CARDIOVASCULAR-DISEASE; CARDIAC-ARRHYTHMIAS; CATHETER ABLATION; RISK-FACTORS; COPD; FIBRILLATION; MORTALITY; HEALTH
Štítky
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 24. 4. 2015 13:21, Ing. Mgr. Věra Pospíšilíková
Anotace
V originále
Chronic obstructive pulmonary disease (COPD) is associated with increased cardiovascular morbidity and mortality, yet the exact pathophysiological links remain unclear. Whether the presence and severity of COPD are associated with atrial or ventricular arrhythmias recorded on continuous electrocardiographic monitoring is unknown. We identified consecutive adult patients who underwent clinically indicated pulmonary function testing as well as 24-hour Holter monitoring at the Mayo Clinic, Rochester, from 2000 to 2009. Demographic data and relevant co-morbidities were gathered from the electronic medical record; severity of COPD was classified according to the GOLD classification, and arrhythmias were classified in concordance with the current clinical guidelines. From 7,441 patients who were included (age 64 +/- 16 years, 49% woman, 92% Caucasian), COPD was diagnosed in 3,121 (41.9%). Compared with those without COPD, the presence and severity of COPD were associated with increased likelihood of atrial fibrillation/atrial flutter (AF/AFL; 23.3% vs 11.0%, respectively, p <0.0001), nonsustained ventricular tachycardia (NSVT; 13.0% vs 5.9%, respectively, p <0.0001), and sustained ventricular tachycardia (0.9% vs 1.6%, respectively, p <0.0001). COPD remained a significant predictor of AF/AFL and NSVT (p <0.0001 and p <0.0001, respectively) after adjusting for age, gender, tobacco use, obesity, hypertension, coronary artery disease, heart failure, diabetes, anemia, cancer, chronic kidney disease, and rate/rhythm control medications. In conclusion, the independent association between the presence and severity of COPD and arrhythmias (AF/AFL and NSVT) provides further insight into the markedly increased cardiovascular mortality of patients with COPD. Further studies should explore which anti-arrhythmic strategies would best apply to the patients with COPD.