J 2015

Prognostic significance of dipping in older hypertensive patients

BENDZALA, Matej, Peter KRUZLIAK, Ludovit GASPAR, Miroslav SOUČEK, Igor MRDOVIC et. al.

Základní údaje

Originální název

Prognostic significance of dipping in older hypertensive patients

Autoři

BENDZALA, Matej (703 Slovensko), Peter KRUZLIAK (203 Česká republika), Ludovit GASPAR (703 Slovensko), Miroslav SOUČEK (203 Česká republika, garant, domácí), Igor MRDOVIC (840 Spojené státy), Peter SABAKA (703 Slovensko), Andrej DUKAT (703 Slovensko), Iveta GASPAROVA (703 Slovensko), Leoné MALAN (710 Jižní Afrika) a Kenji TAKAZAWA (392 Japonsko)

Vydání

Blood Pressure, London, INFORMA HEALTHCARE, 2015, 0803-7051

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 2.010

Kód RIV

RIV/00216224:14110/15:00082504

Organizační jednotka

Lékařská fakulta

UT WoS

000351106200007

Klíčová slova anglicky

5-year mortality; ABPM; arterial hypertension; blood pressure dipping

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 4. 6. 2015 15:14, Ing. Mgr. Věra Pospíšilíková

Anotace

V originále

Abstract Background and aims. Arterial hypertension doubles the risk of coronary heart disease, heart and kidney failure, and peripheral arterial disease. Less variation in diurnal ambulatory blood pressure monitoring (ABPM) patterns may affect mortality outcome. Therefore, as hypertension occurs in over 95% of older subjects, the prognostic value of dipping status in older hypertensive patients will be assessed. Method. The retrospective study group consisted of 170 hypertensive patients, aged 75-84 years, enrolled in the years 2005 to 2007. Baseline measures included 24-h ABPM. Diurnal index and dipping status was calculated and stratified the group into dippers (40 patients, 23.5%), non-dippers (65 patients, 38.2%) and reverse-dippers (65 patients, 38.2%). Results. During a 5-year observation, after baseline we have observed 69 deaths (40.9%) from the whole group of 170 patients with 23 (35.4%) being non-dippers and 36 (55.4%) reverse-dippers. There were significant differences between the groups divided according to diurnal dipping status in survival time, number of recorded deaths and night mean blood pressure. We have identified and confirmed risk factors for the all-cause mortality: age, mean systolic and diastolic blood pressure, diurnal index and dipping status (dipping, non-dipping or reverse-dipping). Conclusion. Reverse-dippers and non-dippers revealed worse prognosis compared with dippers.