A Novel Electrochemical Sensor for the Detection of Purine
Derivatives

D 2013

A Novel Electrochemical Sensor for the Detection of Purine Derivatives

HALOUZKA, Vladimír; Rudolf NAVRÁTIL; Iveta PILAŘOVÁ; František JELEN; Libuše TRNKOVÁ et al.

Základní údaje

Originální název

A Novel Electrochemical Sensor for the Detection of Purine Derivatives

Autoři

HALOUZKA, Vladimír; Rudolf NAVRÁTIL; Iveta PILAŘOVÁ; František JELEN a Libuše TRNKOVÁ

Vydání

1. vyd. Mexico, 64th Annual Meeting of the International Society of Electrochemistry, 1 s. 2013

Nakladatel

International Society of Electrochemistry

Další údaje

Jazyk

angličtina

Typ výsledku

Stať ve sborníku

Obor

10403 Physical chemistry

Stát vydavatele

Mexiko

Utajení

není předmětem státního či obchodního tajemství

Forma vydání

paměťový nosič (CD, DVD, flash disk)

Označené pro přenos do RIV

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova anglicky

electrochemical sensor; purine derivatives; monovalent copper; complex Cu(I)-purine; EVLS;

Štítky

Změněno: 17. 5. 2018 15:07, Ing. Nicole Zrilić

Anotace

V originále

A simple and cheap electrochemical sensor for the sensitive detection of purine derivatives was designed. The purine sensor is based on a graphite electrode modified with cuprous ions. Monovalent copper ions generated in situ on the electrode surface are able to form, with purine derivatives, sparingly soluble complexes strongly adsorbed on the electrode surface. These complexes provide a sensitive qualitative and quantitative monitoring of individual purines and their mixtures not only by means of oxidation signals of Cu(I)-purine complexes but also by means of oxidation signals of the corresponding purine. Signal amplification of the electrochemical sensor consists of both an increase of surface concentration of the purine derivative through adsorption with a low soluble Cu(I)-purine complex and the second signal processing using EVLS – Elimination voltammetry with Linear Scan. The EVLS is an unconventional electrochemical method capable of eliminating selected particular currents (diffusion, charging, kinetic current, etc.) from the total voltammetric current. The elimination procedure is very fast and simple and requires only three total voltammetric curves recorded at three different scan rates. For the sensing, the application of EVLS function E4 (conserving the diffusion current component) has a significant advantage because in the case of adsorbed electroactive species it provides a special peak-counterpeak signal. The invented sensor relates generally to diagnostic systems and methods of improved electrochemical measurement of purines in food, beverage and body fluid samples. Moreover, the simultaneous electrochemical monitoring of metabolites related to the purine catabolism pathway is promising.

Návaznosti

CZ.1.05/1.1.00/02.0068, interní kód MU

Název: CEITEC - středoevropský technologický institut (Akronym: CEITEC)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, CEITEC - středoevropský technologický institut, 1.1 Evropská centra excelence

LH13053, projekt VaV

Název: Chemická a elektrochemická analýza purinových derivátů a jejich komplexů s mědí (Akronym: CECAP)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Chemická a elektrochemická analýza purinových derivátů

MUNI/A/0992/2009, interní kód MU

Název: Vývoj metodologie a instrumentace analytické chemie pro studium složení a vlastností přírodních a syntetických materiálů (Akronym: MIA)

Investor: Masarykova univerzita, Vývoj metodologie a instrumentace analytické chemie pro studium složení a vlastností přírodních a syntetických materiálů, DO R. 2020_Kategorie A - Specifický výzkum - Studentské výzkumné projekty

Citovat

HALOUZKA, Vladimír; Rudolf NAVRÁTIL; Iveta PILAŘOVÁ; František JELEN a Libuše TRNKOVÁ. A Novel Electrochemical Sensor for the Detection of Purine Derivatives. In 64th Annual Meeting of the International Society of Electrochemistry. 1. vyd. Mexico: International Society of Electrochemistry, 2013, 1 s.

@inproceedings{1300807,
   author = {Halouzka, Vladimír and Navrátil, Rudolf and Pilařová, Iveta and Jelen, František and Trnková, Libuše},
   address = {Mexico},
   booktitle = {64th Annual Meeting of the International Society of Electrochemistry},
   edition = {1.},
   keywords = {electrochemical sensor; purine derivatives; monovalent copper; complex Cu(I)-purine; EVLS;},
   howpublished = {paměťový nosič},
   language = {eng},
   location = {Mexico},
   note = {Nepřenášet do RIV - není na WoS ani Scopus, neodpovídá definici druhů výsledků dle M17+},
   publisher = {International Society of Electrochemistry},
   title = {A Novel Electrochemical Sensor for the Detection of Purine Derivatives},
   year = {2013}
}

TY  - CONF
ID  - 1300807
AU  - Halouzka, Vladimír - Navrátil, Rudolf - Pilařová, Iveta - Jelen, František - Trnková, Libuše
PY  - 2013
TI  - A Novel Electrochemical Sensor for the Detection of Purine Derivatives
PB  - International Society of Electrochemistry
CY  - Mexico
N1  - Nepřenášet do RIV - není na WoS ani Scopus, neodpovídá definici druhů výsledků dle M17+
KW  - electrochemical sensor
KW  - purine derivatives
KW  - monovalent copper
KW  - complex Cu(I)-purine
KW  - EVLS;
N2  - A simple and cheap electrochemical sensor for the sensitive detection of purine derivatives was designed. The purine sensor is based on a graphite electrode modified with cuprous ions. Monovalent copper ions generated in situ on the electrode surface are able to form, with purine derivatives, sparingly soluble complexes strongly adsorbed on the electrode surface. These complexes provide a sensitive qualitative and quantitative monitoring of individual purines and their mixtures not only by means of oxidation signals of Cu(I)-purine complexes but also by means of oxidation signals of the corresponding purine. Signal amplification of the electrochemical sensor consists of both an increase of surface concentration of the purine derivative through adsorption with a low soluble Cu(I)-purine complex and the second signal processing using EVLS – Elimination voltammetry with Linear Scan. The EVLS is an unconventional electrochemical method capable of eliminating selected particular currents (diffusion, charging, kinetic current, etc.) from the total voltammetric current. The elimination procedure is very fast and simple and requires only three total voltammetric curves recorded at three different scan rates. For the sensing, the application of EVLS function E4 (conserving the diffusion current component) has a significant advantage because in the case of adsorbed electroactive species it provides a special peak-counterpeak signal. The invented sensor relates generally to diagnostic systems and methods of improved electrochemical measurement of purines in food, beverage and body fluid samples. Moreover, the simultaneous electrochemical monitoring of metabolites related to the purine catabolism pathway is promising.
ER  -

HALOUZKA, Vladimír; Rudolf NAVRÁTIL; Iveta PILAŘOVÁ; František JELEN a Libuše TRNKOVÁ. A Novel Electrochemical Sensor for the Detection of Purine Derivatives. In \textit{64th Annual Meeting of the International Society of Electrochemistry}. 1. vyd. Mexico: International Society of Electrochemistry, 2013, 1 s.

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