A prospective study examining the incidence of asymptomatic and
symptomatic lymphoceles following lymphadenectomy in patients
with gynecological cancer

J 2015

A prospective study examining the incidence of asymptomatic and symptomatic lymphoceles following lymphadenectomy in patients with gynecological cancer

ZIKÁN, Michal; Daniela FISCHEROVA; Ivana PINKAVOVÁ; Jiri SLAMA; Vít WEINBERGER et al.

Základní údaje

Originální název

A prospective study examining the incidence of asymptomatic and symptomatic lymphoceles following lymphadenectomy in patients with gynecological cancer

Autoři

ZIKÁN, Michal; Daniela FISCHEROVA; Ivana PINKAVOVÁ; Jiri SLAMA; Vít WEINBERGER; Ladislav DUŠEK a David CIBULA

Vydání

Gynecologic Oncology, San Diego, Academic Press Inc. Elsevier Science, 2015, 0090-8258

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30214 Obstetrics and gynaecology

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 4.198

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/15:00083164

Organizační jednotka

Lékařská fakulta

DOI

https://doi.org/10.1016/j.ygyno.2015.02.016

UT WoS

000354504100017

EID Scopus

2-s2.0-84933277403

Klíčová slova anglicky

Lymphocele;Pelvic lymphadenectomy; Paraaortic lymphadenectomy; Radical hysterectomy

Štítky

EL OK

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 8. 4. 2016 13:59, Ing. Mgr. Věra Pospíšilíková

Anotace

V originále

Objective. To identify the incidence of asymptomatic and symptomatic (i.e., causing pain, hydronephrosis, venous thrombosis, acute lymphedema of the lower or urinary urgency) lymphoceles, as well as risk factors for their development, through a prospective study of patients undergoing sole pelvic or combined pelvic and paraaortic lymphadenectomy for gynecological cancer. Methods. Patients with endometrial, ovarian or cervical cancer scheduled for sole pelvic or combined pelvic and paraaortic lymphadenectomy as a primary surgical treatment or salvage surgery for recurrence were enrolled at single institution fromFebruary 2006 toNovember 2010 and prospectively followed upwith ultrasound. Results. Of 800 patients who underwent sole pelvic or combined pelvic and paraaortic lymphadenectomy for gynecological cancer, the overall incidence of lymphoceles was 20.2%, with symptomatic lymphoceles occurring in 5.8% of all patients. Lymphoceles are predominantly located on the left pelvic side wall. Lymphadenectomy in ovarian cancer, a higher number of lymph nodes obtained (N27), and radical hysterectomy in cervical cancer were found to be independent risk factors for the development of symptomatic lymphoceles. Conclusions. The overall incidence of lymphocele development after lymphadenectomy for gynecological cancer remains high. However, the majority of lymphoceles are only incidental finding without clinical impact. A symptomatic lymphocele is an uncommon event, occurring in only 5.8% of patients. Symptomatic lymphoceles tend to develop earlier than asymptomatic. Although such risk factors are hard to avoid, patients known to be at an increased risk of developing symptomatic lymphoceles can be counseled appropriately and followed up for specific symptoms relating to lymphocele development.

Citovat

ZIKÁN, Michal; Daniela FISCHEROVA; Ivana PINKAVOVÁ; Jiri SLAMA; Vít WEINBERGER; Ladislav DUŠEK a David CIBULA. A prospective study examining the incidence of asymptomatic and symptomatic lymphoceles following lymphadenectomy in patients with gynecological cancer. Gynecologic Oncology. San Diego: Academic Press Inc. Elsevier Science, 2015, roč. 137, č. 2, s. 291-298. ISSN 0090-8258. Dostupné z: https://doi.org/10.1016/j.ygyno.2015.02.016.

@article{1301249,
   author = {Zikán, Michal and Fischerova, Daniela and Pinkavová, Ivana and Slama, Jiri and Weinberger, Vít and Dušek, Ladislav and Cibula, David},
   article_location = {San Diego},
   article_number = {2},
   doi = {https://doi.org/10.1016/j.ygyno.2015.02.016},
   keywords = {Lymphocele;Pelvic lymphadenectomy; Paraaortic lymphadenectomy; Radical hysterectomy},
   language = {eng},
   issn = {0090-8258},
   journal = {Gynecologic Oncology},
   title = {A prospective study examining the incidence of asymptomatic and symptomatic lymphoceles following lymphadenectomy in patients with gynecological cancer},
   volume = {137},
   year = {2015}
}

TY  - JOUR
ID  - 1301249
AU  - Zikán, Michal - Fischerova, Daniela - Pinkavová, Ivana - Slama, Jiri - Weinberger, Vít - Dušek, Ladislav - Cibula, David
PY  - 2015
TI  - A prospective study examining the incidence of asymptomatic and symptomatic lymphoceles following lymphadenectomy in patients with gynecological cancer
JF  - Gynecologic Oncology
VL  - 137
IS  - 2
SP  - 291-298
EP  - 291-298
PB  - Academic Press Inc. Elsevier Science
SN  - 00908258
KW  - Lymphocele;Pelvic lymphadenectomy
KW  - Paraaortic lymphadenectomy
KW  - Radical hysterectomy
N2  - Objective. To identify the incidence of asymptomatic and symptomatic (i.e., causing pain, hydronephrosis, venous thrombosis, acute lymphedema of the lower or urinary urgency) lymphoceles, as well as risk factors for their development, through a prospective study of patients undergoing sole pelvic or combined pelvic and paraaortic lymphadenectomy for gynecological cancer. Methods. Patients with endometrial, ovarian or cervical cancer scheduled for sole pelvic or combined pelvic and paraaortic lymphadenectomy as a primary surgical treatment or salvage surgery for recurrence were enrolled at single institution fromFebruary 2006 toNovember 2010 and prospectively followed upwith ultrasound. Results. Of 800 patients who underwent sole pelvic or combined pelvic and paraaortic lymphadenectomy for gynecological cancer, the overall incidence of lymphoceles was 20.2%, with symptomatic lymphoceles occurring in 5.8% of all patients. Lymphoceles are predominantly located on the left pelvic side wall. Lymphadenectomy in ovarian cancer, a higher number of lymph nodes obtained (N27), and radical hysterectomy in cervical cancer were found to be independent risk factors for the development of symptomatic lymphoceles. Conclusions. The overall incidence of lymphocele development after lymphadenectomy for gynecological cancer remains high. However, the majority of lymphoceles are only incidental finding without clinical impact. A symptomatic lymphocele is an uncommon event, occurring in only 5.8% of patients. Symptomatic lymphoceles tend to develop earlier than asymptomatic. Although such risk factors are hard to avoid, patients known to be at an increased risk of developing symptomatic lymphoceles can be counseled appropriately and followed up for specific symptoms relating to lymphocele development.
ER  -

ZIKÁN, Michal; Daniela FISCHEROVA; Ivana PINKAVOVÁ; Jiri SLAMA; Vít WEINBERGER; Ladislav DUŠEK a David CIBULA. A prospective study examining the incidence of asymptomatic and symptomatic lymphoceles following lymphadenectomy in patients with gynecological cancer. \textit{Gynecologic Oncology}. San Diego: Academic Press Inc. Elsevier Science, 2015, roč.~137, č.~2, s.~291-298. ISSN~0090-8258. Dostupné z: https://doi.org/10.1016/j.ygyno.2015.02.016.

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