The A allele of cluster of differentiation 36 (CD36) SNP
1761667 associates with decreased lipid taste perception in
obese Tunisian women.

J 2015

The A allele of cluster of differentiation 36 (CD36) SNP 1761667 associates with decreased lipid taste perception in obese Tunisian women.

MRIZAK, Ines; Omar ŠERÝ; Jiří PLESNÍK; Amel ARFA; Mariem FEKIH et al.

Základní údaje

Originální název

The A allele of cluster of differentiation 36 (CD36) SNP 1761667 associates with decreased lipid taste perception in obese Tunisian women.

Autoři

MRIZAK, Ines; Omar ŠERÝ; Jiří PLESNÍK; Amel ARFA; Mariem FEKIH; Ali BOUSLEMA; Monia ZAOUALI; Zouhair ZABKA a Naim Akhtar KHAN

Vydání

British Journal of Nutrition, Cambridge University Press, 2015, 0007-1145

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30202 Endocrinology and metabolism

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 3.311

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/15:00083199

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova česky

obezity, lipidy, chuť, geny

Klíčová slova anglicky

obesity; lipids; taste; genes

Štítky

AKR, rivok

Změněno: 25. 5. 2017 17:20, Ing. Nicole Zrilić

Anotace

V originále

Recent studies have suggested that excessive intake of dietary fat is associated with obesity. Some obese subjects have been reported to exhibit high thresholds for the gustatory detection of lipids via lipid receptors, such as cluster of differentiation 36 (CD36). We studied lingual detection thresholds for emulsions containing oleic acid in obese Tunisian women (n 203) using a three-alternative forced choice (3-AFC) method. Genotyping of the TNF-a (rs1800629), IL-6 (rs1800795) and CD36 (rs1761667) genes was performed to associate with lipid taste perception thresholds. The CD36 genotype distribution was as follows: GG (n 42), AG (n 102) and AA (n 59). Women with the CD36 GG genotype exhibited oral detection thresholds for oleic acid that were more than three times lower than those with the CD36 AA genotype. The present study confirms a high threshold of gustatory fat detection in obese women with the CD36 AA genotype, but there is no significant association with the IL-6 and TNF-a gene polymorphisms.

Citovat

MRIZAK, Ines; Omar ŠERÝ; Jiří PLESNÍK; Amel ARFA; Mariem FEKIH; Ali BOUSLEMA; Monia ZAOUALI; Zouhair ZABKA a Naim Akhtar KHAN. The A allele of cluster of differentiation 36 (CD36) SNP 1761667 associates with decreased lipid taste perception in obese Tunisian women. British Journal of Nutrition. Cambridge University Press, 2015, roč. 113, č. 8, s. 1330-1337. ISSN 0007-1145. Dostupné z: https://doi.org/10.1017/S0007114515000343.

@article{1301503,
   author = {Mrizak, Ines and Šerý, Omar and Plesník, Jiří and Arfa, Amel and Fekih, Mariem and Bouslema, Ali and Zaouali, Monia and Zabka, Zouhair and Khan, Naim Akhtar},
   article_number = {8},
   doi = {https://doi.org/10.1017/S0007114515000343},
   keywords = {obesity; lipids; taste; genes},
   language = {eng},
   issn = {0007-1145},
   journal = {British Journal of Nutrition},
   note = {Opraven obor publikace},
   title = {The A allele of cluster of differentiation 36 (CD36) SNP 1761667 associates with decreased lipid taste perception in obese Tunisian women.},
   volume = {113},
   year = {2015}
}

TY  - JOUR
ID  - 1301503
AU  - Mrizak, Ines - Šerý, Omar - Plesník, Jiří - Arfa, Amel - Fekih, Mariem - Bouslema, Ali - Zaouali, Monia - Zabka, Zouhair - Khan, Naim Akhtar
PY  - 2015
TI  - The A allele of cluster of differentiation 36 (CD36) SNP 1761667 associates with decreased lipid taste perception in obese Tunisian women.
JF  - British Journal of Nutrition
VL  - 113
IS  - 8
SP  - 1330-1337
EP  - 1330-1337
PB  - Cambridge University Press
SN  - 00071145
N1  - Opraven obor publikace
KW  - obesity
KW  - lipids
KW  - taste
KW  - genes
N2  - Recent studies have suggested that excessive intake of dietary fat is associated with obesity. Some obese subjects have been reported to exhibit high thresholds for the gustatory detection of lipids via lipid receptors, such as cluster of differentiation 36 (CD36). We studied lingual detection thresholds for emulsions containing oleic acid in obese Tunisian women (n 203) using a three-alternative forced choice (3-AFC) method. Genotyping of the TNF-a (rs1800629), IL-6 (rs1800795) and CD36 (rs1761667) genes was performed to associate with lipid taste perception thresholds. The CD36 genotype distribution was as follows: GG (n 42), AG (n 102) and AA (n 59). Women with the CD36 GG genotype exhibited oral detection thresholds for oleic acid that were more than three times lower than those with the CD36 AA genotype. The present study confirms a high threshold of gustatory fat detection in obese women with the CD36 AA genotype, but there is no significant association with the IL-6 and TNF-a gene polymorphisms.
ER  -

MRIZAK, Ines; Omar ŠERÝ; Jiří PLESNÍK; Amel ARFA; Mariem FEKIH; Ali BOUSLEMA; Monia ZAOUALI; Zouhair ZABKA a Naim Akhtar KHAN. The A allele of cluster of differentiation 36 (CD36) SNP 1761667 associates with decreased lipid taste perception in obese Tunisian women. \textit{British Journal of Nutrition}. Cambridge University Press, 2015, roč.~113, č.~8, s.~1330-1337. ISSN~0007-1145. Dostupné z: https://doi.org/10.1017/S0007114515000343.

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