Surgical Methods in Mouse Tooth Autotransplantation Research

LANGOVÁ, Petra, Jan ŠTEMBÍREK, Martina POKORNÁ, Michal NAVRÁTIL, Eva MATALOVÁ a marcela BUCHTOVÁ. Surgical Methods in Mouse Tooth Autotransplantation Research. In IBMS BoneKEy 13, The 4th Joint Meeting of ECTS and IBMS. 2015. ISSN 1940-8692. Dostupné z: https://dx.doi.org/10.1038/bonekey.2015.53.

Základní údaje

• Originální název: Surgical Methods in Mouse Tooth Autotransplantation Research
• Název česky: Chirurgické metody při výzkumu autotransplantace zubů u myší
• Autoři: LANGOVÁ, Petra, Jan ŠTEMBÍREK, Martina POKORNÁ, Michal NAVRÁTIL, Eva MATALOVÁ a marcela BUCHTOVÁ.
• Vydání: IBMS BoneKEy 13, The 4th Joint Meeting of ECTS and IBMS, 2015.

Další údaje

• Originální jazyk: angličtina
• Typ výsledku: Konferenční abstrakt
• Obor: 30200 3.2 Clinical medicine
• Stát vydavatele: Nizozemské království
• Utajení: není předmětem státního či obchodního tajemství
• Organizační jednotka: Lékařská fakulta
• ISSN: 1940-8692
• Doi: http://dx.doi.org/10.1038/bonekey.2015.53
• Klíčová slova česky: ankylóza, reinervace, revaskularizace
• Klíčová slova anglicky: ankylosis, reinnervation, revascularisation

Anotace

Autotransplantation of teeth is one of the possibilities to substitute the missing teeth in the dental arch. In comparison with prosthetic dentistry and implantology, autogenous transplantation is the most natural way of tooth replacement. Although success and advantages are prevailing, there are some complications like ankylosis or inflammation, which have to be solved. To understand regenerative processes after autotransplantations, several animal models and histological/molecular methods have been established. We review recent achievements in autotransplantation techniques with using animal models and the evaluation of advantages and disadvantages of their using as showed also in our experiments. The most common laboratory animals used in autotransplantation research are mice and rats. Despite the monophyodont dentition and reduced dental formula together with hypsodont incisors and toothless diastema, numerous findings can be successfully extrapolated from rodents to humans. Various parameters of successful autotransplantation such as periodontal tissue regeneration, reinnervation or revascularisation have already been proved in the mouse. The autotransplantation of teeth currently has a firm place in the field of dentistry because of preserving the physiological properties of teeth, periodontal and alveolar bone.

Anotace česky

Autotransplantace zubů je jednou z možností, jak v zubním oblouku nahradit chybějící zuby. Tato metoda je oproti protetickému či implantologickému řešení přirozenou cestou náhrady chrupu. Ačkoli převažují výhody a úspěch, setkáváme se při operacích i s komplikacemi, které musejí být následně řešeny, jako jsou ankylóza nebo zánět. To understand regenerative processes after autotransplantations, several animal models and histological/molecular methods have been established. We review recent achievements in autotransplantation techniques with using animal models and the evaluation of advantages and disadvantages of their using as showed also in our experiments. The most common laboratory animals used in autotransplantation research are mice and rats. Despite the monophyodont dentition and reduced dental formula together with hypsodont incisors and toothless diastema, numerous findings can be successfully extrapolated from rodents to humans. Various parameters of successful autotransplantation such as periodontal tissue regeneration, reinnervation or revascularisation have already been proved in the mouse. The autotransplantation of teeth currently has a firm place in the field of dentistry because of preserving the physiological properties of teeth, periodontal and alveolar bone.

Návaznosti

• NT11420, projekt VaV: Název: Molekulární diagnostika hypodoncie a možnosti zubních autotransplantací