2015
Microarray analysis of mandible regionalization during mouse development
LANGOVÁ, Petra; Simona MORAVCOVÁ BALKOVÁ a marcela BUCHTOVÁZákladní údaje
Originální název
Microarray analysis of mandible regionalization during mouse development
Autoři
LANGOVÁ, Petra; Simona MORAVCOVÁ BALKOVÁ a marcela BUCHTOVÁ
Vydání
Morphology 2015, 2015
Další údaje
Jazyk
angličtina
Typ výsledku
Konferenční abstrakt
Obor
30200 3.2 Clinical medicine
Stát vydavatele
Česká republika
Utajení
není předmětem státního či obchodního tajemství
Impakt faktor
Impact factor: 0.924
Označené pro přenos do RIV
Ano
Kód RIV
RIV/00216224:14110/15:00081215
Organizační jednotka
Lékařská fakulta
ISSN
Klíčová slova anglicky
odontogenesis; gene expression
Změněno: 6. 4. 2016 14:51, Ing. Mgr. Věra Pospíšilíková
Anotace
V originále
The mammalian teeth function to capture and chew food and they have become specialized for these purposes producing a complex and distinctive dentition consisting of unicuspid and multicuspid teeth. To achieve this specialization, tooth development is characterized by a complex series of reciprocal interactions that occur between the epithelium and the underlying cranial neural crest-derived mesenchyme that regulates tooth morphogenesis and differentiation at molecular level. Up to now several homeobox genes are known to be expressed in specific pattern of mouse mandible that specifies the incisor and molar area. However, there are still many unsolved questions how complex signaling between the epithelium and mesenchyme is regulated during initial development of different classes of teeth. To reveal these complex molecular bases of tooth development, a polygenetic approach is needed. Here, we aim to uncover signaling cascades between the oral epithelium and mesenchyme along the jaw that underlay heterodont dentition in mammals.
Návaznosti
| GB14-37368G, projekt VaV |
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