Modulatory Effects of Eschscholzia californica Alkaloids on
Recombinant GABAA Receptors

J 2015

Modulatory Effects of Eschscholzia californica Alkaloids on Recombinant GABAA Receptors

FEDURCO, Milan; Jana GREGOROVÁ; Kristýna ŠEBRLOVÁ; Jana KANTOROVÁ; Ondřej PEŠ et al.

Základní údaje

Originální název

Modulatory Effects of Eschscholzia californica Alkaloids on Recombinant GABAA Receptors

Autoři

FEDURCO, Milan; Jana GREGOROVÁ ; Kristýna ŠEBRLOVÁ; Jana KANTOROVÁ; Ondřej PEŠ; Roland BAUR; Erwin SIGEL a Eva TÁBORSKÁ

Vydání

Biochemistry Research International, New York, Hindawi Publishing Corporation, 2015, 2090-2247

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10600 1.6 Biological sciences

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/15:00084850

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

Escholzia californica; alkaloids; gaba receptors; mass spectrometry

Štítky

EL OK

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 26. 11. 2015 12:23, Soňa Böhmová

Anotace

V originále

The California poppy (Eschscholzia californica Cham.) contains a variety of natural compounds including several alkaloids found exclusively in this plant. Because of the sedative, anxiolytic, and analgesic effects, this herb is currently sold in pharmacies in many countries. However, our understanding of these biological effects at the molecular level is still lacking. Alkaloids detected in E. californica could be hypothesized to act at GABAA receptors, which are widely expressed in the brain mainly at the inhibitory interneurons.

Citovat

FEDURCO, Milan; Jana GREGOROVÁ; Kristýna ŠEBRLOVÁ; Jana KANTOROVÁ; Ondřej PEŠ; Roland BAUR; Erwin SIGEL a Eva TÁBORSKÁ. Modulatory Effects of Eschscholzia californica Alkaloids on Recombinant GABAA Receptors. Biochemistry Research International. New York: Hindawi Publishing Corporation, 2015, roč. 2015, UNSP 617620, s. 1-9. ISSN 2090-2247. Dostupné z: https://doi.org/10.1155/2015/617620.

@article{1318521,
   author = {Fedurco, Milan and Gregorová, Jana and Šebrlová, Kristýna and Kantorová, Jana and Peš, Ondřej and Baur, Roland and Sigel, Erwin and Táborská, Eva},
   article_location = {New York},
   article_number = {UNSP 617620},
   doi = {https://doi.org/10.1155/2015/617620},
   keywords = {Escholzia californica; alkaloids; gaba receptors; mass spectrometry},
   language = {eng},
   issn = {2090-2247},
   journal = {Biochemistry Research International},
   title = {Modulatory Effects of Eschscholzia californica Alkaloids on Recombinant GABAA Receptors},
   volume = {2015},
   year = {2015}
}

TY  - JOUR
ID  - 1318521
AU  - Fedurco, Milan - Gregorová, Jana - Šebrlová, Kristýna - Kantorová, Jana - Peš, Ondřej - Baur, Roland - Sigel, Erwin - Táborská, Eva
PY  - 2015
TI  - Modulatory Effects of Eschscholzia californica Alkaloids on Recombinant GABAA Receptors
JF  - Biochemistry Research International
VL  - 2015
IS  - UNSP 617620
SP  - 1-9
EP  - 1-9
PB  - Hindawi Publishing Corporation
SN  - 20902247
KW  - Escholzia californica
KW  - alkaloids
KW  - gaba receptors
KW  - mass spectrometry
N2  - The California poppy (Eschscholzia californica Cham.) contains a variety of natural compounds including several alkaloids found exclusively in this plant. Because of the sedative, anxiolytic, and analgesic effects, this herb is currently sold in pharmacies in many countries. However, our understanding of these biological effects at the molecular level is still lacking. Alkaloids detected in E. californica could be hypothesized to act at GABAA receptors, which are widely expressed in the brain mainly at the inhibitory interneurons.
ER  -

FEDURCO, Milan; Jana GREGOROVÁ; Kristýna ŠEBRLOVÁ; Jana KANTOROVÁ; Ondřej PEŠ; Roland BAUR; Erwin SIGEL a Eva TÁBORSKÁ. Modulatory Effects of Eschscholzia californica Alkaloids on Recombinant GABAA Receptors. \textit{Biochemistry Research International}. New York: Hindawi Publishing Corporation, 2015, roč.~2015, UNSP 617620, s.~1-9. ISSN~2090-2247. Dostupné z: https://doi.org/10.1155/2015/617620.

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