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@article{1318802, author = {Sevcikova, M. and Modra, H. and Blahova, J. and Dobsikova, R. and Kalina, Jiří and Zitka, O. and Kizek, R. and Svobodova, Z.}, article_location = {New York}, article_number = {4}, doi = {http://dx.doi.org/10.1007/s00244-015-0213-0}, keywords = {TROUT ONCORHYNCHUS-MYKISS; SALMON SALMO-SALAR; OXIDATIVE STRESS; LIZA-AURATA; DIETARY METHYLMERCURY; LIPID-PEROXIDATION; AQUATIC ORGANISMS; BIOACCUMULATION; GLUTATHIONE; EXPOSURE}, language = {eng}, issn = {0090-4341}, journal = {Archives of Environmental Contamination and Toxicology}, title = {Factors Affecting Antioxidant Response in Fish from a Long-term Mercury-Contaminated Reservoir}, volume = {69}, year = {2015} }
TY - JOUR ID - 1318802 AU - Sevcikova, M. - Modra, H. - Blahova, J. - Dobsikova, R. - Kalina, Jiří - Zitka, O. - Kizek, R. - Svobodova, Z. PY - 2015 TI - Factors Affecting Antioxidant Response in Fish from a Long-term Mercury-Contaminated Reservoir JF - Archives of Environmental Contamination and Toxicology VL - 69 IS - 4 SP - 431-439 EP - 431-439 PB - Springer-Verlag SN - 00904341 KW - TROUT ONCORHYNCHUS-MYKISS KW - SALMON SALMO-SALAR KW - OXIDATIVE STRESS KW - LIZA-AURATA KW - DIETARY METHYLMERCURY KW - LIPID-PEROXIDATION KW - AQUATIC ORGANISMS KW - BIOACCUMULATION KW - GLUTATHIONE KW - EXPOSURE N2 - The objective of this work was to evaluate antioxidant defence and oxidative damage in organs (liver, gills, kidney, and brain) of five fish species (Aspius aspius, Esox lucius, Sander lucioperca, Abramis brama, Rutilus rutilus) from the long-term mercury-contaminated Skalka Reservoir in the Czech Republic. Special emphasis was placed on a comprehensive assessment of the factors that may affect the antioxidant response to mercury in fish. Antioxidant enzymes (glutathione reductase, glutathione peroxidase, and glutathione-S-transferase) did not significantly respond to mercury contamination. Levels of the analysed enzymes and oxidative damage to lipids were predominantly determined by a separate organ factor or species factor, or by the combination of both (p < 0.001). Levels of total glutathione and the reduced/oxidized glutathione ratio were influenced by mercury contamination in combination with their specific organ distribution (p < 0.001). Our results suggest that species and type of organ alone or in combination are more important factors than chronic exposure to mercury contamination with respect to effects on antioxidant defence in fish under field conditions. Our findings suggest that the main antioxidant defensive mechanism in fish from the studied long-term mercury contaminated site was the inter-tissue distribution of glutathione. ER -
SEVCIKOVA, M., H. MODRA, J. BLAHOVA, R. DOBSIKOVA, Jiří KALINA, O. ZITKA, R. KIZEK a Z. SVOBODOVA. Factors Affecting Antioxidant Response in Fish from a Long-term Mercury-Contaminated Reservoir. \textit{Archives of Environmental Contamination and Toxicology}. New York: Springer-Verlag, 2015, roč.~69, č.~4, s.~431-439. ISSN~0090-4341. Dostupné z: https://dx.doi.org/10.1007/s00244-015-0213-0.
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