Structural covariance mapping delineates medial and
medio-lateral temporal networks in déja vu

J 2016

Structural covariance mapping delineates medial and medio-lateral temporal networks in déja vu

SHAW, Daniel Joel; Radek MAREČEK a Milan BRÁZDIL

Základní údaje

Originální název

Structural covariance mapping delineates medial and medio-lateral temporal networks in déja vu

Autoři

SHAW, Daniel Joel; Radek MAREČEK a Milan BRÁZDIL

Vydání

Brain Imaging and Behavior, New York, Springer, 2016, 1931-7557

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.985

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14740/16:00089250

Organizační jednotka

Středoevropský technologický institut

Klíčová slova anglicky

Déja vu; Grey matter; Memory; Meta-analytic connectivity modelling; Structural co-variance

Štítky

rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 19. 1. 2017 10:14, Mgr. Eva Špillingová

Anotace

V originále

Déja vu (DV) is an eerie phenomenon experienced frequently as an aura of temporal lobe epilepsy, but also reported commonly by healthy individuals. The former pathological manifestation appears to result from aberrant neural activity among brain structures within the medial temporal lobes. Recent studies also implicate medial temporal brain structures in the non-pathological experience of DV, but as one element of a diffuse neuroanatomical correlate; it remains to be seen if neural activity among the medial temporal lobes also underlies this benign manifestation. The present study set out to investigate this. Due to its unpredictable and infrequent occurrence, however, non-pathological DV does not lend itself easily to functional neuroimaging. Instead, we draw on research showing that brain structure covaries among regions that interact frequently as nodes of functional networks. Specifically, we assessed whether grey-matter covariance among structures implicated in non-pathological DV differs according to the frequency with which the phenomenon is experienced. This revealed two diverging patterns of structural covariation: Among the first, comprised primarily of medial temporal structures and the caudate, grey-matter volume becomes more positively correlated with higher frequency of DV experience. The second pattern encompasses medial and lateral temporal structures, among which greater DV frequency is associated with more negatively correlated grey matter. Using a meta-analytic method of co-activation mapping, we demonstrate a higher probability of functional interactions among brain structures constituting the former pattern, particularly during memory-related processes. Our findings suggest that altered neural signalling within memory-related medial temporal brain structures underlies both pathological and non-pathological DV.

Návaznosti

ED1.1.00/02.0068, projekt VaV

Název: CEITEC - central european institute of technology

Citovat

SHAW, Daniel Joel; Radek MAREČEK a Milan BRÁZDIL. Structural covariance mapping delineates medial and medio-lateral temporal networks in déja vu. Brain Imaging and Behavior. New York: Springer, 2016, roč. 10, č. 4, s. 1068-1079. ISSN 1931-7557. Dostupné z: https://doi.org/10.1007/s11682-015-9471-8.

@article{1323729,
   author = {Shaw, Daniel Joel and Mareček, Radek and Brázdil, Milan},
   article_location = {New York},
   article_number = {4},
   doi = {https://doi.org/10.1007/s11682-015-9471-8},
   keywords = {Déja vu; Grey matter; Memory; Meta-analytic connectivity modelling; Structural co-variance},
   language = {eng},
   issn = {1931-7557},
   journal = {Brain Imaging and Behavior},
   title = {Structural covariance mapping delineates medial and medio-lateral temporal networks in déja vu},
   url = {http://link.springer.com/article/10.1007%2Fs11682-015-9471-8},
   volume = {10},
   year = {2016}
}

TY  - JOUR
ID  - 1323729
AU  - Shaw, Daniel Joel - Mareček, Radek - Brázdil, Milan
PY  - 2016
TI  - Structural covariance mapping delineates medial and medio-lateral temporal networks in déja vu
JF  - Brain Imaging and Behavior
VL  - 10
IS  - 4
SP  - 1068-1079
EP  - 1068-1079
PB  - Springer
SN  - 19317557
KW  - Déja vu
KW  - Grey matter
KW  - Memory
KW  - Meta-analytic connectivity modelling
KW  - Structural co-variance
UR  - http://link.springer.com/article/10.1007%2Fs11682-015-9471-8
L2  - http://link.springer.com/article/10.1007%2Fs11682-015-9471-8
N2  - Déja vu (DV) is an eerie phenomenon experienced frequently as an aura of temporal lobe epilepsy, but also reported commonly by healthy individuals. The former pathological manifestation appears to result from aberrant neural activity among brain structures within the medial temporal lobes. Recent studies also implicate medial temporal brain structures in the non-pathological experience of DV, but as one element of a diffuse neuroanatomical correlate; it remains to be seen if neural activity among the medial temporal lobes also underlies this benign manifestation. The present study set out to investigate this. Due to its unpredictable and infrequent occurrence, however, non-pathological DV does not lend itself easily to functional neuroimaging. Instead, we draw on research showing that brain structure covaries among regions that interact frequently as nodes of functional networks. Specifically, we assessed whether grey-matter covariance among structures implicated in non-pathological DV differs according to the frequency with which the phenomenon is experienced. This revealed two diverging patterns of structural covariation: Among the first, comprised primarily of medial temporal structures and the caudate, grey-matter volume becomes more positively correlated with higher frequency of DV experience. The second pattern encompasses medial and lateral temporal structures, among which greater DV frequency is associated with more negatively correlated grey matter. Using a meta-analytic method of co-activation mapping, we demonstrate a higher probability of functional interactions among brain structures constituting the former pattern, particularly during memory-related processes. Our findings suggest that altered neural signalling within memory-related medial temporal brain structures underlies both pathological and non-pathological DV.
ER  -

SHAW, Daniel Joel; Radek MAREČEK a Milan BRÁZDIL. Structural covariance mapping delineates medial and medio-lateral temporal networks in déja vu. \textit{Brain Imaging and Behavior}. New York: Springer, 2016, roč.~10, č.~4, s.~1068-1079. ISSN~1931-7557. Dostupné z: https://doi.org/10.1007/s11682-015-9471-8.

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