Prognostic value of stress-only and stress-rest normal gated
SPECT imaging: higher incidence of cardiac hard events in
diabetic patients who underwent full stress-rest imaging

J 2015

Prognostic value of stress-only and stress-rest normal gated SPECT imaging: higher incidence of cardiac hard events in diabetic patients who underwent full stress-rest imaging

KAMINEK, Milan, Iva METELKOVA, Miroslava BUDIKOVA, Lenka HENZLOVA, Pavel KORANDA et. al.

Základní údaje

Originální název

Prognostic value of stress-only and stress-rest normal gated SPECT imaging: higher incidence of cardiac hard events in diabetic patients who underwent full stress-rest imaging

Autoři

KAMINEK, Milan (203 Česká republika), Iva METELKOVA (203 Česká republika), Miroslava BUDIKOVA (203 Česká republika), Lenka HENZLOVA (203 Česká republika), Pavel KORANDA (203 Česká republika), Vladimír KINCL (203 Česká republika, garant, domácí) a Adéla DROZDOVÁ (203 Česká republika, domácí)

Vydání

Biomedical Papers of the Faculty of Medicine of Palacký University, Olomouc, Palacký University, 2015, 1213-8118

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 0.924

Kód RIV

RIV/00216224:14110/15:00086553

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.5507/bp.2014.024

UT WoS

000364948100020

Klíčová slova anglicky

myocardial perfusion imaging; coronary artery disease; prognosis; stress-only imaging; diabetes mellitus

Štítky

EL OK

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 11. 2. 2016 17:11, Ing. Mgr. Věra Pospíšilíková

Anotace

V originále

Background. The European procedural guidelines for cardiac gated SPECT imaging demonstrate considerable variability in recommended administered radiopharmaceutical activity and imaging protocols. This study compared stress-only and stress-rest protocols to evaluate the safety of stress-only imaging, and to identify characteristics of patients who need full stress-rest imaging. Methods. Patients referred for a chest pain were scheduled for stress-rest gated SPECT imaging. If the stress images were interpreted as normal according to the perfusion and left ventricular function, the examination of patients was finished and patients did not undergo the rest imaging. A total number of 1063 patients was included (mean age 61 +/- 11 years). These patients have been followed for hard cardiac events, i.e. cardiac deaths or nonfatal myocardial infarction. Results. During a follow-up of 3.2 +/- 2.5 years, hard events occurred in 12 patients with normal SPECT and 59 with abnormal SPECT had hard events (0.7 vs. 3.6% /year, P < 0.001). Among the 536 patients with normal study, there was no significantly lower incidence of hard events in the subgroup of patients with stress-only imaging (0.6 vs. 0.8% /year, P = 0.641). Diabetes mellitus was an independent predictor of hard events in patients with normal SPECT (1.3 vs. 0.5%/year, P < 0.001). We found a higher incidence of hard events in diabetic patients with normal study with the necessity of full stress-rest imaging in comparison with those with stress-only imaging (1.7 vs. 0.7% /year, P < 0.001). Conclusions. Our results support the good prognosis of normal stress-only study. Diabetes mellitus was an independent predictor of hard events in patients with normal SPECT. Diabetic patients with normal results who required additional rest imaging had significant adverse outcome.

Citovat

KAMINEK, Milan, Iva METELKOVA, Miroslava BUDIKOVA, Lenka HENZLOVA, Pavel KORANDA, Vladimír KINCL a Adéla DROZDOVÁ. Prognostic value of stress-only and stress-rest normal gated SPECT imaging: higher incidence of cardiac hard events in diabetic patients who underwent full stress-rest imaging. Biomedical Papers of the Faculty of Medicine of Palacký University. Olomouc: Palacký University, 2015, roč. 159, č. 3, s. 455-459. ISSN 1213-8118. Dostupné z: https://dx.doi.org/10.5507/bp.2014.024.

@article{1335137,
   author = {Kaminek, Milan and Metelkova, Iva and Budikova, Miroslava and Henzlova, Lenka and Koranda, Pavel and Kincl, Vladimír and Drozdová, Adéla},
   article_location = {Olomouc},
   article_number = {3},
   doi = {http://dx.doi.org/10.5507/bp.2014.024},
   keywords = {myocardial perfusion imaging; coronary artery disease; prognosis; stress-only imaging; diabetes mellitus},
   language = {eng},
   issn = {1213-8118},
   journal = {Biomedical Papers of the Faculty of Medicine of Palacký University},
   title = {Prognostic value of stress-only and stress-rest normal gated SPECT imaging: higher incidence of cardiac hard events in diabetic patients who underwent full stress-rest imaging},
   volume = {159},
   year = {2015}
}

TY  - JOUR
ID  - 1335137
AU  - Kaminek, Milan - Metelkova, Iva - Budikova, Miroslava - Henzlova, Lenka - Koranda, Pavel - Kincl, Vladimír - Drozdová, Adéla
PY  - 2015
TI  - Prognostic value of stress-only and stress-rest normal gated SPECT imaging: higher incidence of cardiac hard events in diabetic patients who underwent full stress-rest imaging
JF  - Biomedical Papers of the Faculty of Medicine of Palacký University
VL  - 159
IS  - 3
SP  - 455-459
EP  - 455-459
PB  - Palacký University
SN  - 12138118
KW  - myocardial perfusion imaging
KW  - coronary artery disease
KW  - prognosis
KW  - stress-only imaging
KW  - diabetes mellitus
N2  - Background. The European procedural guidelines for cardiac gated SPECT imaging demonstrate considerable variability in recommended administered radiopharmaceutical activity and imaging protocols. This study compared stress-only and stress-rest protocols to evaluate the safety of stress-only imaging, and to identify characteristics of patients who need full stress-rest imaging. Methods. Patients referred for a chest pain were scheduled for stress-rest gated SPECT imaging. If the stress images were interpreted as normal according to the perfusion and left ventricular function, the examination of patients was finished and patients did not undergo the rest imaging. A total number of 1063 patients was included (mean age 61 +/- 11 years). These patients have been followed for hard cardiac events, i.e. cardiac deaths or nonfatal myocardial infarction. Results. During a follow-up of 3.2 +/- 2.5 years, hard events occurred in 12 patients with normal SPECT and 59 with abnormal SPECT had hard events (0.7 vs. 3.6% /year, P < 0.001). Among the 536 patients with normal study, there was no significantly lower incidence of hard events in the subgroup of patients with stress-only imaging (0.6 vs. 0.8% /year, P = 0.641). Diabetes mellitus was an independent predictor of hard events in patients with normal SPECT (1.3 vs. 0.5%/year, P < 0.001). We found a higher incidence of hard events in diabetic patients with normal study with the necessity of full stress-rest imaging in comparison with those with stress-only imaging (1.7 vs. 0.7% /year, P < 0.001). Conclusions. Our results support the good prognosis of normal stress-only study. Diabetes mellitus was an independent predictor of hard events in patients with normal SPECT. Diabetic patients with normal results who required additional rest imaging had significant adverse outcome.
ER  -

KAMINEK, Milan, Iva METELKOVA, Miroslava BUDIKOVA, Lenka HENZLOVA, Pavel KORANDA, Vladimír KINCL a Adéla DROZDOVÁ. Prognostic value of stress-only and stress-rest normal gated SPECT imaging: higher incidence of cardiac hard events in diabetic patients who underwent full stress-rest imaging. \textit{Biomedical Papers of the Faculty of Medicine of Palacký University}. Olomouc: Palacký University, 2015, roč.~159, č.~3, s.~455-459. ISSN~1213-8118. Dostupné z: https://dx.doi.org/10.5507/bp.2014.024.

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