J 2015

Unusual way of suicide by carbon monoxide

ZELENÝ, Michal, Jan PIVNIČKA, Martin ŠINDLER a Pavel KUKLETA

Základní údaje

Originální název

Unusual way of suicide by carbon monoxide

Autoři

ZELENÝ, Michal (203 Česká republika, garant, domácí), Jan PIVNIČKA (203 Česká republika, domácí), Martin ŠINDLER (203 Česká republika, domácí) a Pavel KUKLETA (203 Česká republika)

Vydání

Neuroendocrinology Letters, Stockholm, Maghira and Maas Publications, 2015, 0172-780X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30202 Endocrinology and metabolism

Stát vydavatele

Švédsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 0.946

Kód RIV

RIV/00216224:14110/15:00087005

Organizační jednotka

Lékařská fakulta

UT WoS

000369404400022

Klíčová slova anglicky

suicide; carbon monoxide; carboxyhemoglobin; gas chromatography; forensic toxicology

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 20. 4. 2016 11:13, Ing. Mgr. Věra Pospíšilíková

Anotace

V originále

OBJECTIVES: Authors discuss the case of a suicide of a 29-year-old man caused by carbon monoxide (CO) intoxication. What the authors found interesting was the unusual way of committing suicide that required good technical skills and expert knowledge. METHODS: The level of carboxyhemoglobin (COHb) in the blood of the deceased man was routinely determined by the modified method by Blackmoore (1970), using gas chromatography/thermal conductivity detection. The level of saturation of the hemoglobin by CO in the collected blood sample is determined relatively to the same sample saturated to 100%. RESULTS: In the blood sample of the deceased man the lethal concentration of COHb of 76.5% was determined. Within the following examinations the blood alcohol concentration of 0.05 g.kg(-1) was determined. Further analysis revealed traces of sertraline, its metabolite N-desmethylsertraline, omeprazole and caffeine in the liver tissue, traces of N-desmethylsertraline, ibuprofen and caffeine in urine sample, and only traces of caffeine in the stomach content and blood samples were proved. To commit suicide the man used a sophisticated double container-system equipped with a timer for controlled generation of CO based on the chemical reaction of concentrated sulphuric acid and formic acid. The used timer was set by an electromechanical timer switch that triggered the fatal reaction of the acids while the man was sleeping. CONCLUSIONS: The authors discuss an unusual case of suicide by CO intoxication rarely seen in the area of forensic medicine and toxicology that is specific due to its sophisticated way of execution.