J 2016

Long-term follow-up after bioresorbable vascular scaffold implantation in STEMI patients: PRAGUE-19 study update

TOUŠEK, Petr; Viktor KOČKA; Martin MALÝ; Martin KOZEL; Robert PETR et al.

Základní údaje

Originální název

Long-term follow-up after bioresorbable vascular scaffold implantation in STEMI patients: PRAGUE-19 study update

Autoři

TOUŠEK, Petr; Viktor KOČKA; Martin MALÝ; Martin KOZEL; Robert PETR; Martin HAJSL; Jiří JARKOVSKÝ ORCID; Libor LISA; Tomáš BUDĚŠÍNSKÝ a Petr WIDIMSKÝ

Vydání

EuroIntervention, Toulouse, Europa Edition, 2016, 1774-024X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Francie

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 5.193

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/16:00090040

Organizační jednotka

Lékařská fakulta

EID Scopus

Klíčová slova anglicky

bioresorbable vascular scaffold; long-term follow-up; optical coherence tomography; ST-elevation myocardial infarction

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 4. 8. 2016 10:15, Ing. Mgr. Věra Pospíšilíková

Anotace

V originále

Aims: Early clinical results after implantation of bioresorbable vascular scaffolds (BVS) in ST-elevation myocardial infarction (STEMI) are encouraging, but long-term data are missing. This study evaluates longterm outcome in STEMI patients with implanted BVS. Methods and results: The PRAGUE-19 study is an academic study enrolling consecutive STEMI patients with the intention to implant BVS. A total of 580 STEMI patients were screened between December 2012 and March 2015; 117 patients fulfilled entry criteria and BVS was successfully implanted in 114 (97%) of them. The primary combined clinical endpoint (death, reinfarction or target vessel revascularisation) occurred in 11.5% during the mean follow-up period of 730±275 days with overall mortality of 4.4%. Definite scaffold thrombosis occurred in two patients in the early phase after BVS implantation; there was no late thrombosis. Quantitative coronary angiography (10 patients) at three years demonstrated late lumen loss of 0.2±0.33 mm and optical coherence tomography showed minimal lumen area of 5.3±1.37 mm2 and neointimal hyperplasia area of 2.9±0.48 mm2. BVS struts were still visible at three years and 99.4% of them were well apposed and covered. Conclusions: Encouraging clinical and imaging results after BVS implantation in STEMI patients persist during long-term follow-up.