J 2017

Single-Phase Versus Multiphase CT Angiography in Middle Cerebral Artery Clot Detection-Benefits for Less Experienced Radiologists and Neurologists

VOLNÝ, Ondřej; Petra CIMFLOVÁ; Pavla KADLECOVA; Petr VANĚK; Jiří VANÍČEK et. al.

Základní údaje

Originální název

Single-Phase Versus Multiphase CT Angiography in Middle Cerebral Artery Clot Detection-Benefits for Less Experienced Radiologists and Neurologists

Autoři

VOLNÝ, Ondřej; Petra CIMFLOVÁ; Pavla KADLECOVA; Petr VANĚK; Jiří VANÍČEK; Bijoy K. MENON a Robert MIKULÍK

Vydání

Journal of Stroke & Cerebrovascular Diseases, Amsterdam, Elsevier Science Inc. 2017, 1052-3057

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30103 Neurosciences

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 1.598

Kód RIV

RIV/00216224:14110/17:00095976

Organizační jednotka

Lékařská fakulta

UT WoS

000396430100013

EID Scopus

2-s2.0-84995445038

Klíčová slova anglicky

Acute stroke; CT angiography; Distal clot; Middle cerebral artery; Multiphase CTA

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 20. 3. 2018 11:46, Soňa Böhmová

Anotace

V originále

Objectives: CT angiography (CTA) is recommended as a standard of stroke imaging. We investigated accuracy and precision of standard or single-phase CTA as compared with novel technique or multiphase CTA in clot detection in the middle cerebral artery. Methods: Twenty single-phase CTA and twenty multiphase CTA with prevailing M2 occlusion were assessed by 10 radiologists and 10 neurologists blinded to clinical information (7 less experienced and 3 experienced). Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated as compared with reading by two seniors. Reliability was calculated using Krippendorff's alpha (K-alpha). Results: Sensitivity, specificity, PPV, and NPV of single-phase CTA compared with multiphase CTA for M2 clot presence were, respectively, .86, .75, .90, and .67 versus .88, .82, .92, and .72. For secondary or distal clots, sensitivity, specificity, PPV, and NPV of single-phase CTA compared with multiphase CTA were .41, .83, .50, and .78 versus .65, .77, .71, and .67. Agreement increased significantly in favor of multiphase CTA for detection of primary clots from moderate (.43) to substantial (.65) in less experienced radiologists and from slight (.10) to moderate (.30) in less experienced neurologists. Agreement significantly increased for distal or secondary clot detection in favor of multiphase CTA from fair (.24) to moderate (.49) in experienced radiologists and from slight (.12) to moderate (.46) in experienced neurologists. Conclusions: Multiphase CTA is a reliable imaging tool in M2 clot detection and might represent a beneficial imaging tool in clot detection for less experienced physicians.