Nitro-Oleic Acid Prevents Hypoxia-and Asymmetric
Dimethylarginine-Induced Pulmonary Endothelial Dysfunction

J 2016

Nitro-Oleic Acid Prevents Hypoxia-and Asymmetric Dimethylarginine-Induced Pulmonary Endothelial Dysfunction

KOUDELKA, Adolf; Gabriela AMBROŽOVÁ; Anna KLINKE; Táňa FIDLEROVÁ; Hana VEREŠČÁKOVÁ et al.

Základní údaje

Originální název

Nitro-Oleic Acid Prevents Hypoxia-and Asymmetric Dimethylarginine-Induced Pulmonary Endothelial Dysfunction

Autoři

Vydání

Cardiovascular Drugs and Therapy, Springer, 2016, 0920-3206

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.820

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/16:00114974

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova anglicky

Nitro-oleic acid; Asymmetric dimethylarginine; Hypoxia; Pulmonary hypertension; Human pulmonary artery endothelial cell

Štítky

rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 10. 6. 2020 16:02, Mgr. Marie Novosadová Šípková, DiS.

Anotace

V originále

Pulmonary hypertension (PH) represents a serious health complication accompanied with hypoxic conditions, elevated levels of asymmetric dimethylarginine (ADMA), and overall dysfunction of pulmonary vascular endothelium. Since the prevention strategies for treatment of PH remain largely unknown, our study aimed to explore the effect of nitro-oleic acid (OA-NO2), an exemplary nitro-fatty acid (NO2-FA), in human pulmonary artery endothelial cells (HPAEC) under the influence of hypoxia or ADMA.

Citovat

KOUDELKA, Adolf; Gabriela AMBROŽOVÁ; Anna KLINKE; Táňa FIDLEROVÁ; Hana VEREŠČÁKOVÁ; Radek KUCHTA; Tanja K RUDOLPH; Jaroslav KADLEC; Zdenka KUCHTOVA; Steven R. WOODCOCK; Bruce A. FREEMAN; Lukáš KUBALA a Michaela PEKAROVÁ. Nitro-Oleic Acid Prevents Hypoxia-and Asymmetric Dimethylarginine-Induced Pulmonary Endothelial Dysfunction. Cardiovascular Drugs and Therapy. Springer, 2016, roč. 30, č. 6, s. 579-586. ISSN 0920-3206. Dostupné z: https://doi.org/10.1007/s10557-016-6700-3.

@article{1368562,
   author = {Koudelka, Adolf and Ambrožová, Gabriela and Klinke, Anna and Fidlerová, Táňa and Vereščáková, Hana and Kuchta, Radek and Rudolph, Tanja K and Kadlec, Jaroslav and Kuchtova, Zdenka and Woodcock, Steven R. and Freeman, Bruce A. and Kubala, Lukáš and Pekarová, Michaela},
   article_number = {6},
   doi = {https://doi.org/10.1007/s10557-016-6700-3},
   keywords = {Nitro-oleic acid; Asymmetric dimethylarginine; Hypoxia; Pulmonary hypertension; Human pulmonary artery endothelial cell},
   language = {eng},
   issn = {0920-3206},
   journal = {Cardiovascular Drugs and Therapy},
   title = {Nitro-Oleic Acid Prevents Hypoxia-and Asymmetric Dimethylarginine-Induced Pulmonary Endothelial Dysfunction},
   url = {http://link.springer.com/article/10.1007/s10557-016-6700-3},
   volume = {30},
   year = {2016}
}

TY  - JOUR
ID  - 1368562
AU  - Koudelka, Adolf - Ambrožová, Gabriela - Klinke, Anna - Fidlerová, Táňa - Vereščáková, Hana - Kuchta, Radek - Rudolph, Tanja K - Kadlec, Jaroslav - Kuchtova, Zdenka - Woodcock, Steven R. - Freeman, Bruce A. - Kubala, Lukáš - Pekarová, Michaela
PY  - 2016
TI  - Nitro-Oleic Acid Prevents Hypoxia-and Asymmetric Dimethylarginine-Induced Pulmonary Endothelial Dysfunction
JF  - Cardiovascular Drugs and Therapy
VL  - 30
IS  - 6
SP  - 579-586
EP  - 579-586
PB  - Springer
SN  - 09203206
KW  - Nitro-oleic acid
KW  - Asymmetric dimethylarginine
KW  - Hypoxia
KW  - Pulmonary hypertension
KW  - Human pulmonary artery endothelial cell
UR  - http://link.springer.com/article/10.1007/s10557-016-6700-3
L2  - http://link.springer.com/article/10.1007/s10557-016-6700-3
N2  - Pulmonary hypertension (PH) represents a serious health complication accompanied with hypoxic conditions, elevated levels of asymmetric dimethylarginine (ADMA), and overall dysfunction of pulmonary vascular endothelium. Since the prevention strategies for treatment of PH remain largely unknown, our study aimed to explore the effect of nitro-oleic acid (OA-NO2), an exemplary nitro-fatty acid (NO2-FA), in human pulmonary artery endothelial cells (HPAEC) under the influence of hypoxia or ADMA.
ER  -

KOUDELKA, Adolf; Gabriela AMBROŽOVÁ; Anna KLINKE; Táňa FIDLEROVÁ; Hana VEREŠČÁKOVÁ; Radek KUCHTA; Tanja K RUDOLPH; Jaroslav KADLEC; Zdenka KUCHTOVA; Steven R. WOODCOCK; Bruce A. FREEMAN; Lukáš KUBALA a Michaela PEKAROVÁ. Nitro-Oleic Acid Prevents Hypoxia-and Asymmetric Dimethylarginine-Induced Pulmonary Endothelial Dysfunction. \textit{Cardiovascular Drugs and Therapy}. Springer, 2016, roč.~30, č.~6, s.~579-586. ISSN~0920-3206. Dostupné z: https://doi.org/10.1007/s10557-016-6700-3.

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