A novel method for heterocyclic amide–thioamide transformations

HASSAN, Walid Fathalla M.; Ibrahim A. I. ALI and Pavel PAZDERA. A novel method for heterocyclic amide–thioamide transformations. Beilstein Journal of Organic Chemistry. 2017, vol. 13, June, p. 174-181. ISSN 1860-5397. Available from: https://doi.org/10.3762/bjoc.13.20.

Basic information

Original name

A novel method for heterocyclic amide–thioamide transformations

Authors

HASSAN, Walid Fathalla M. (818 Egypt, belonging to the institution); Ibrahim A. I. ALI (818 Egypt) and Pavel PAZDERA (203 Czech Republic, guarantor, belonging to the institution)

Edition

Beilstein Journal of Organic Chemistry, 2017, 1860-5397

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Other information

Language

English

Type of outcome

Article in a journal

Field of Study

10401 Organic chemistry

Country of publisher

Germany

Confidentiality degree

is not subject to a state or trade secret

References:

URL

Impact factor

Impact factor: 2.330

RIV identification code

RIV/00216224:14310/17:00096105

Organization unit

Faculty of Science

DOI

https://doi.org/10.3762/bjoc.13.20

UT WoS

000395042800001

EID Scopus

2-s2.0-85011915875

Keywords in English

heterocyclic amides; heterocyclic thioamides; N-cyclohexyl dithiocarbamate cyclohexylammonium salt; novel thiating agent; thiation

Tags

NZ, rivok

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Abstract

In the original language

In this paper, we introduce a novel and convenient method for the transformation of heterocyclic amides into heteocyclic thioamides. A two-step approach was applied for this transformation: Firstly, we applied a chlorination of the heterocyclic amides to afford the corresponding chloroheterocycles. Secondly, the chloroherocycles and N-cyclohexyl dithiocarbamate cyclohexylammonium salt were heated in chloroform for 12 h at 61 °C to afford heteocyclic thioamides in excellent yields.